Best Cat Glucosamine Supplements (2026) – Top 10 Reviewed
Watching your cat struggle to jump onto their favorite perch or hesitate at the stairs is heartbreaking. Joint stiffness and discomfort are incredibly common in aging felines, and glucosamine supplements can help support cartilage health, ease inflammation, and keep your cat moving comfortably. In this guide, we’ve reviewed the best glucosamine supplements for cats to help you find the right one for your furry friend.
Our Top Picks at a Glance
- Best Overall: Nutramax Cosequin Joint Health Soft Chews – Trusted vet-recommended formula with glucosamine and chondroitin
- Best Value: Paramount Pet Health Liquid Glucosamine for Cats – Affordable liquid with 260mg glucosamine per serving
- Best Premium: Nutramax Dasuquin Joint Health Supplement – Advanced formula with ASU and boswellia
Quick Comparison
| Product | Key Ingredients | Form | Servings | Best For |
|---|---|---|---|---|
| Nutramax Cosequin Soft Chews | Glucosamine HCl, Chondroitin, Omega-3s | Soft Chews | 60 | Overall joint support |
| Paramount Pet Health Liquid Glucosamine | Glucosamine 260mg, MSM, Chondroitin, Taurine | Liquid | 2oz bottle | Budget-friendly liquid option |
| Nutramax Dasuquin Capsules | Glucosamine, Chondroitin, ASU, Boswellia, Green Tea | Capsules | 84 | Advanced joint support |
| Pet Honesty Cat Hip & Joint Chews | Glucosamine, Chondroitin, Omega-3s | Crunchy & Creamy Chews | 30-day supply | Picky eaters |
| Liquid-Vet Feline Hip & Joint | Glucosamine 400mg, MSM, HA, Chondroitin | Liquid | Varies | High-dose glucosamine |
| VetriScience GlycoFlex Chews | Glucosamine, Green-Lipped Mussel | Chews | 60 | Mobility and joint protection |
| WONDER PAWS Liquid Glucosamine | Collagen, Glucosamine, Chondroitin, MSM, Taurine, HA | Liquid | 2oz bottle | Comprehensive joint formula |
| LIQUIDHEALTH Joint Purr-Fection | Glucosamine, Chondroitin, Hyaluronic Acid | Liquid | 2oz bottle | Senior cats and kittens |
| Nutramax Cosequin Sprinkle Capsules | Glucosamine HCl, Chondroitin | Sprinkle Capsules | 80 | Mixing into food |
| NODENS Cat Hip and Joint Glucosamine | Glucosamine, Chondroitin, Hyaluronic Acid | Liquid | Varies | Inflammation and flexibility |
1. Nutramax Cosequin Joint Health Soft Chews – Best Overall
No products found.
Cosequin is the most trusted name in pet joint supplements, and their soft chews for cats are easy to administer and vet-recommended.
These soft chews feature glucosamine hydrochloride (FCHG49) and sodium chondroitin sulfate (TRH122) as the primary active ingredients — both are research-backed compounds that promote cartilage repair. Omega-3 fatty acids from fish oil provide additional anti-inflammatory support. The round, squishy chews are ideally sized for cats and have an aroma that most felines find appealing.
What We Like
- Number one vet-recommended joint supplement brand for cats
- Contains clinically studied glucosamine and chondroitin forms
- Includes omega-3s for added anti-inflammatory benefits
What Could Be Better
- Initial loading dose requires twice the maintenance amount
- May take several weeks to show noticeable improvement
Bottom Line: Nutramax Cosequin is the industry standard for feline joint support — proven, vet-recommended, and accepted by most cats.
2. Paramount Pet Health Liquid Glucosamine for Cats – Best Value
- Easy to Mix with Food: No more struggling with pills or chews; our liquid glucosamine chondroitin for cats blends seamlessly into wet or dry food and is absorbed into the system faster than tablets or treats for quick, effective joint support
- Supports Healthy Mobility: Each serving provides 260 mg glucosamine, 50 mg chondroitin, and 120 mg MSM to help maintain joint flexibility and comfort; Ideal for senior cats or those needing extra hip and joint care as part of their daily wellness routine
- Promotes Long-Term Joint Health: This feline joint supplement is formulated to help nourish cartilage and support fluid movement in joints; keeping your cat active, comfortable, and moving with ease through every stage of life
- Gentle, Palatable Formula: Designed with picky eaters in mind, these liquid glucosamine drops mix easily with food without affecting flavor or texture; Perfect for everyday use to help maintain mobility and overall joint health in cats
- Trusted Quality & Satisfaction: Made with premium ingredients and crafted with care, this hip and joint support for cats fits seamlessly into your pet’s routine; If you’re not fully satisfied, contact us, we’ll make it right
This affordable liquid formula delivers 260mg of glucosamine per serving along with MSM, chondroitin, taurine, and hyaluronic acid.
Paramount Pet Health created this supplement after the founder’s own cat experienced joint issues. Each 2ml serving provides a robust blend of joint-supporting ingredients including 260mg glucosamine, 120mg MSM, 50mg chondroitin, 100mg taurine, and 10mg hyaluronic acid. The beef-flavored liquid mixes easily into wet food, making it ideal for cats who refuse pills or chews.
What We Like
- Excellent price-to-value ratio with comprehensive ingredients
- Includes taurine, an essential amino acid for cats
- Manufactured in an FDA-compliant, cGMP-certified facility in the USA
What Could Be Better
- Some cats may detect the beef flavor in their food
- Requires refrigeration for extended shelf life
Bottom Line: Paramount Pet Health delivers one of the most complete liquid glucosamine formulas on the market at an unbeatable price.
3. Nutramax Dasuquin Joint Health Supplement – Best Premium
No products found.
Dasuquin goes beyond basic glucosamine with an advanced formula featuring ASU, boswellia, and green tea extract.
This premium supplement from Nutramax includes avocado/soybean unsaponifiables (ASU) alongside glucosamine and chondroitin. ASU has been shown to help protect cartilage and support joint function at the cellular level. The addition of boswellia serrata extract and green tea extract provides powerful anti-inflammatory and antioxidant support. Available in both capsule and soft chew formats.
What We Like
- Most advanced joint supplement formula available for cats
- ASU provides unique cartilage-protective benefits
- Backed by extensive clinical research
What Could Be Better
- Higher price point than basic glucosamine supplements
- Capsule format requires opening and sprinkling on food
Bottom Line: If your cat has significant joint issues or you want the most comprehensive joint support available, Dasuquin is worth the investment.
4. Pet Honesty Cat Hip & Joint Health Chews
- 〖Indoor Outdoor Front Door Mat Size〗16x24in=40x60cm.Perfect size for home, office, dormitory, industrial, commercial deal etc high traffic place.
- 〖Non-Slip Kitchen Rug〗Non-woven surface, backing with non-slip rubber, firm edge wrapping, safe and anti-slip, stay in place, lightweight and durable, wear-resistant and stain-resistant, low profile design to prevent tripping.
- 〖Decorative Doormat〗One side printed mats with vivid colors and good look, perfect for birthday, family gathering, wedding, anniversary, fall/autumn Thanksgiving, Halloween, Christmas or theme party decoration, add chic atmosphere to holiday.
- 〖Multi-purpose Welcome Mat〗Both indoor and outdoor use, suitable for front door, porch, entrance way, kitchen, bathroom, bedroom, living room, patio, balcony, terrace, home gym, garden, back door, dining room, classroom, laundry room, garage, etc, effectively captures dust&keep the environment tidy.
- 〖Washable Floor Mat〗Easy to clean, machine washable, no bleach, no fade and no shrink after washing, lay flat and dry naturally or simply vacuum with a hand-held vacuum, sweep with a broom, or shake off outdoors or over your garbage, for a deeper clean, wipe with a damp cloth and mild soap, or use a garden hose to rinse the mat outdoors. Allow your mat to fully air dry before next use.
These dual-textured chews — crunchy outside, creamy inside — are specifically designed to appeal to picky cats.
Pet Honesty’s unique crunchy and creamy format makes these chews feel more like treats than supplements. They contain glucosamine, chondroitin, and omega-3 fatty acids to support joint mobility, flexibility, and comfort. The chicken flavor is highly palatable, and the chews are appropriately sized for cats of all breeds. Each bag provides a 30-day supply.
What We Like
- Unique dual-texture format cats love
- Over 13,000 positive reviews from cat owners
- Convenient treat-like format requires no food mixing
What Could Be Better
- Only a 30-day supply per bag
- Lower glucosamine concentration than some liquid alternatives
Bottom Line: If your cat won’t take pills, powders, or liquids, Pet Honesty’s treat-like chews are the easiest way to deliver daily joint support.
5. Liquid-Vet Feline Hip & Joint Advanced Formula
- No More Hassles: Liquid-Vet Feline Hip & Joint Advanced Formula makes dosing time easy. No hiding pills in treats, wasting powders and sprinkles, forcing down chews —just 1 SIMPLE dose per day given during mealtime with this tasty gravy-like textured liquid. Cats crave the flavor, and you’ll love the ease of supporting their hip and joint health every day, hassle-free, GUARANTEED.
- Contains ALL the KEY Ingredients for Joint Health: This advanced formula SAVES you $$$ with the vet by combining MAX levels of glucosamine PLUS, MSM, chondroitin, and hyaluronic acid all in one to support joints and hock health. Each ingredient is carefully selected and in the right proportion to help maintain flexibility and mobility in every dose, perfect for keeping your horse active and comfortable.
- Great for Picky Eaters and Cats with Bad Teeth: With delicious natural flavors like chicken, seafood, and even an allergy-friendly unflavored option, even the fussiest cats will eagerly lap it up. This unique formula gives cats the joint support they need in flavor options they enjoy (as well as an allergy-friendly unflavored option), so they’ll never turn up their nose at when it comes time for you to provide them with the health benefits that your cats deserve.
- Made in the USA with the Highest-Levels of Trusted and Proven Ingredients: Liquid-Vet is crafted in our own USA facility using high-quality ingredients from trusted sources. Pet owners can feel confident about giving their cats safe, reliable support for joint health every day.
- Dosing Made Simple for Every Cat Size: With easy dosing instructions based on your cat’s weight, Liquid-Vet Feline Hip & Joint is ideal for cats of all ages and sizes. From small breeds to large breeds and kittens to older adult feline companions, it’s simple to measure the right dose for the best support.
With an industry-leading 400mg of glucosamine per dose, this liquid supplement packs the most potent formula available.
Liquid-Vet’s advanced formula delivers the highest glucosamine dose you’ll find in a feline supplement — 400mg per serving — along with MSM, hyaluronic acid, and chondroitin. The company offers multiple flavor options to accommodate even the pickiest eaters. Simply dose during mealtime once daily with no mixing required. It’s also backed by a two-week money-back guarantee.
What We Like
- Highest glucosamine dose available (400mg per serving)
- Multiple flavor options for picky cats
- Two-week money-back satisfaction guarantee
What Could Be Better
- Requires more product per dose than competing liquids
- Some flavors may not appeal to all cats
Bottom Line: For cats needing maximum glucosamine dosing, Liquid-Vet’s potent formula delivers more of the active ingredient per serving than any competitor.
6. VetriScience GlycoFlex Chews for Cats
No products found.
These chicken-flavored chews combine glucosamine with green-lipped mussel for powerful joint protection and mobility support.
VetriScience’s GlycoFlex uses perna canaliculus (green-lipped mussel) alongside glucosamine HCl to provide a broad spectrum of joint-supporting nutrients including naturally occurring omega-3 fatty acids and glycosaminoglycans. The chicken-flavored chews carry the NASC quality seal, ensuring they meet strict manufacturing and quality standards.
What We Like
- Green-lipped mussel provides natural anti-inflammatory compounds
- NASC quality seal for verified safety and quality
- Available in both standard and extra-strength formulas
What Could Be Better
- Some cats may not find the chew texture appealing
- Barley flour base may not suit grain-sensitive cats
Bottom Line: VetriScience’s green-lipped mussel and glucosamine combination offers a research-backed approach to feline joint health.
7. WONDER PAWS Liquid Glucosamine for Cats
No products found.
This all-in-one liquid formula combines collagen, glucosamine, chondroitin, MSM, taurine, and hyaluronic acid for comprehensive joint care.
WONDER PAWS goes beyond basic glucosamine by including collagen for connective tissue support and taurine for overall feline health. The chicken-flavored liquid is highly bioavailable, meaning your cat’s body can absorb and utilize the nutrients quickly. It supports flexibility, mobility, and joint strength for cats of all ages and activity levels.
What We Like
- Most comprehensive ingredient list in its class
- Includes collagen for added connective tissue support
- Chicken flavor for high palatability
What Could Be Better
- Newer brand with less long-term track record
- Small 2oz bottle may require frequent reordering
Bottom Line: WONDER PAWS offers the most well-rounded liquid glucosamine formula, with six active ingredients working together for complete joint support.
8. LIQUIDHEALTH Pets Joint Purr-Fection
No products found.
This USA-made liquid supplement is specifically designed for feline hip and joint health with fast-absorbing ingredients.
LIQUIDHEALTH’s Joint Purr-Fection uses glucosamine, chondroitin, and hyaluronic acid in a liquid format that ensures faster absorption than pills or chews. The product is suitable for cats of all ages and sizes, from kittens to seniors, and can be administered directly or mixed with food. It carries the NASC quality seal for added confidence in safety and quality.
What We Like
- NASC quality seal for verified manufacturing standards
- Liquid format ensures fast absorption
- Suitable for cats of all ages, including kittens
What Could Be Better
- Small bottle size means frequent repurchasing
- Some cats may not enjoy the taste without flavor masking
Bottom Line: LIQUIDHEALTH delivers a fast-absorbing, NASC-certified liquid glucosamine that’s gentle enough for kittens yet effective for senior cats.
9. Nutramax Cosequin Sprinkle Capsules
No products found.
These easy-to-open capsules let you sprinkle clinically studied joint support directly onto your cat’s food.
The sprinkle capsule format of Cosequin offers the same trusted glucosamine HCl and chondroitin formula as the soft chews but in a form you can open and mix directly into wet or dry food. This makes it ideal for cats who refuse chews or liquids. The fine powder inside the capsules blends easily without altering the texture of your cat’s meal.
What We Like
- Same trusted Cosequin formula in a mixable format
- Fine powder blends seamlessly into food
- 80-count bottle provides excellent value
What Could Be Better
- Requires manually opening capsules each day
- Powder may be detected by cats with very sensitive palates
Bottom Line: If your cat refuses chews and liquids, Cosequin sprinkle capsules offer a stealthy way to deliver vet-recommended joint support through their food.
10. NODENS Cat Hip and Joint Glucosamine
- Give your cat a new lease of life and eliminate kitty’s hip and joint pain for good with Nodens natural and effective cat joint pain relief remedy. Manage your cats joint discomfort with our proven formula. Vets agree a cat joint supplement helps reduce inflammation pain associated with cat arthritis & degenerative joint conditions.
- Nodens powerful liquid formula convenient and easy to feed with your cat’s daily meals. Only the best will do for your fur kid. Even the fussiest feline will lap this up. Super absorption liquid glucosamine for cats, better than pills and powders. Tasty natural meat flavor, even picky cats love it. 2oz bottle lasts up to 2 months.
- Do your cat a favor with Nodens cat health supplies high quality unbeaten human grade ingredients. Safe and natural joint repair nutrients reversing the effects of joint damage to get your best friend moving and enjoying life again. 260mg Glucosamine, 50mg Chondroitin, 10mg Hyaluronic acid, 120mg MSM, 100mg Taurine.
- Senior cat joint supplement, as they age their joints can become stiff and sore. Nodens joint supplement for cats supports cartilage health for improved joint flexibility and lubrication. Helps protect your fur baby from further cartilage breakdown, for a happier, more active and pain free pet. Proudly made in the USA.
- Your kitty will have visible relief. Nodens cat hip and joint supplement drops, arthritis relief for cats. Safe doses of the most widely used joint ingredients available in one liquid joint supplement for cats. Nutritional support to maintain healthy joints, ligaments and cartilage.
This natural liquid supplement targets inflammation and improved flexibility with a straightforward glucosamine and chondroitin formula.
NODENS provides a clean, no-frills approach to feline joint support with glucosamine, chondroitin, and hyaluronic acid in a liquid form. It’s designed to reduce inflammation, improve joint flexibility, and ease discomfort in cats of all ages. The liquid format is easy to administer and is well-received by most cats when mixed with their regular food.
What We Like
- Straightforward formula focused on core joint-supporting ingredients
- Includes hyaluronic acid for joint lubrication
- Popular choice with consistently positive reviews
What Could Be Better
- Doesn’t include extras like taurine or collagen
- Flavor may not appeal to every cat
Bottom Line: NODENS is a solid, reliable liquid glucosamine option for cat owners who want a clean formula without unnecessary additives.
How to Choose the Best Cat Glucosamine Supplement
The first consideration when choosing a glucosamine supplement for your cat is the form of delivery. Cats are notoriously particular about what they consume, so you’ll want to select a format your cat will actually accept. Liquids that mix into wet food are often the easiest to administer, while some cats happily eat flavored chews as treats. Sprinkle capsules offer a middle ground for cats who reject chews but tolerate powders on their food.
Pay attention to the glucosamine dosage per serving. Most veterinarians recommend 120-500mg of glucosamine daily for cats, depending on their weight and the severity of their joint issues. Products with higher glucosamine concentrations generally deliver better results, especially for cats with more advanced joint conditions.
Look for supplements that include complementary ingredients like chondroitin, MSM, hyaluronic acid, and omega-3 fatty acids. Chondroitin helps cartilage retain water and elasticity, MSM supports the body’s ability to absorb glucosamine, and hyaluronic acid lubricates joints. These ingredients work synergistically with glucosamine for more comprehensive joint support.
Quality certifications matter. Look for the NASC quality seal, cGMP manufacturing compliance, and products manufactured in the USA. These markers indicate the supplement has been produced under strict quality control standards. Brands like Nutramax have extensive clinical research backing their specific ingredient forms, which provides additional confidence in their effectiveness.
Finally, consider your cat’s specific needs. A young cat with early joint stiffness may do well with a basic glucosamine and chondroitin supplement, while a senior cat with advanced arthritis may benefit from a premium formula with ASU, boswellia, or green-lipped mussel for enhanced anti-inflammatory support.
Benefits of Glucosamine Supplements for Cats
Glucosamine is a naturally occurring compound found in healthy cartilage. As cats age or experience joint damage, their bodies may not produce enough glucosamine to keep up with cartilage repair and maintenance. Supplemental glucosamine helps fill this gap, supporting the ongoing health and resilience of joint cartilage throughout your cat’s life.
One of the most significant benefits of glucosamine supplementation is improved mobility. Cat owners frequently report that their senior cats return to jumping, climbing, and playing after starting a glucosamine supplement. By supporting cartilage health and reducing inflammation, glucosamine can help your cat move more freely and with less discomfort.
Glucosamine supplements also serve a valuable preventive role. Starting joint supplementation before your cat shows signs of stiffness can help protect their cartilage and delay the onset of age-related joint issues. Many veterinarians recommend beginning glucosamine supplementation in middle-aged cats, particularly for breeds predisposed to joint problems.
Beyond joint health, many glucosamine supplements for cats include ingredients that support overall wellness. Taurine is essential for feline heart, eye, and digestive health. Omega-3 fatty acids support skin, coat, and cardiovascular function. These multi-benefit formulas make daily supplementation even more valuable for your cat’s long-term health.
Frequently Asked Questions
At what age should I start giving my cat glucosamine?
There’s no universal age, but many veterinarians recommend starting glucosamine supplementation around age 7-8, when cats enter their senior years. If your cat shows signs of joint stiffness or reduced mobility earlier, your vet may recommend starting sooner. Some breeds predisposed to joint issues can benefit from earlier supplementation.
How long does it take for glucosamine to work in cats?
Most cats show noticeable improvement within 4-6 weeks of consistent daily supplementation. Some products recommend a higher “loading dose” for the first week or two to help build up levels in the body more quickly. Patience and consistency are key — glucosamine works gradually to support cartilage repair.
Can glucosamine supplements interact with my cat’s medications?
Glucosamine is generally considered safe and well-tolerated, but you should always inform your veterinarian about any supplements your cat is taking. Cats on blood-thinning medications or those with diabetes should be monitored, as glucosamine may have mild effects on blood sugar and clotting.
Is liquid or chew form better for cats?
Neither form is inherently better — the best choice depends on your cat’s preferences. Liquid supplements generally offer faster absorption and are easier to mix discreetly into food. Chews can double as treats and don’t require any preparation. Try whichever form you think your cat will accept most readily.
What are the signs my cat needs a joint supplement?
Watch for behaviors like reluctance to jump up or down, hesitating before leaping, difficulty using the litter box, decreased playfulness, stiffness after resting, overgrooming their hips or legs, and changes in gait. If you notice any of these signs, consult your veterinarian and consider starting a joint supplement.
Are there any side effects of glucosamine for cats?
Side effects are uncommon but may include mild digestive upset such as soft stool or decreased appetite when first starting the supplement. These typically resolve within a few days as your cat adjusts. If symptoms persist, discontinue use and consult your veterinarian.
Can I give my cat a dog glucosamine supplement?
While many glucosamine ingredients are the same, cat-specific formulations are preferred because they account for the smaller size and unique metabolic needs of cats. Dog supplements may contain dosages or additional ingredients that aren’t appropriate for felines. Always choose a product specifically formulated for cats.
Should I combine glucosamine with other joint support strategies?
Yes, glucosamine works best as part of a comprehensive joint care approach. Maintaining a healthy weight reduces stress on joints, regular gentle play keeps muscles strong, and providing comfortable resting areas helps ease strain. Your vet may also recommend anti-inflammatory medications or physical therapy alongside supplementation.
