Best Supplements for Raynaud’s Syndrome (2026) – Top 10 Reviewed
Raynaud’s syndrome causes fingers and toes to feel numb and cold in response to stress or cold temperatures as blood vessels narrow excessively. While medical management is important, certain supplements can help improve circulation and reduce the frequency and severity of Raynaud’s attacks. This guide reviews the best supplements for supporting vascular health in Raynaud’s syndrome.
Our Top Picks at a Glance
- Best Overall: 1MD Nutrition CardioFitMD – comprehensive nitric oxide support
- Best Value: Snap Supplements L-Arginine – effective circulation boost
- Best for Prevention: Luma Omega 3 Fish Oil – anti-inflammatory protection
Quick Comparison
| Product | Key Ingredients | Form | Servings | Best For |
|---|---|---|---|---|
| 1MD CardioFitMD | Beet Root, Nitric Oxide | Capsules | 60 | Overall support |
| Snap L-Arginine | L-Arginine, L-Citrulline | Capsules | 120 | Best value |
| Luma Omega 3 | 2000mg EPA & DHA | Softgels | 120 | Prevention |
| Raw Beet Root Powder | Cold Pressed Beets | Powder | 90 | Maximum potency |
| ZEBORA CoQ10 400mg | CoQ10, PQQ, Omega-3 | Softgels | 120 | Vascular health |
| Snap Beet Gummies | Organic Beets | Gummies | 60 | Easy compliance |
| Sugar Free Beet Gummies | Beet Root, Coconut Oil | Gummies | 60 | Sugar-free |
| Circulation Support | Cayenne, Garlic, Niacin | Capsules | 120 | Warming herbs |
1. 1MD Nutrition CardioFitMD – Best Overall
- Comprehensive & Convenient Nutrition: CardioFitMD is the ultimate, all-in-one superfood drink with a broad-spectrum fiber and prebiotics blend, Bacillus coagulans probiotic, and 20 key letter vitamins and minerals, to provide balanced nutrition every day.*
- Broad-Spectrum Dietary Fiber: Our proprietary broad-spectrum fiber and prebiotic blend contain 29% of the recommended daily serving. With only 5% of Americans getting enough fiber, CardioFitMD helps close the ‘fiber gap’ so you can support proper digestive, heart, and whole-body health.*
- Promote Nitric Oxide Production: The production of nitric oxide, an essential neurotransmitter, slows as part of normal aging. Our potent beetroot powder provides optimum levels of nitric oxide
- Proper Stamina & Healthy Weight Management: One scoop a day can help support energy levels. With proper stamina, you can maximize your fitness routine and promote healthy weight management.*
This physician-formulated supplement provides comprehensive nitric oxide support to help prevent and reduce Raynaud’s attacks.
CardioFitMD combines organic beet root with synergistic ingredients designed to boost nitric oxide production—crucial for Raynaud’s management since nitric oxide helps blood vessels relax and resist excessive constriction. By improving baseline vascular function, this formula may reduce both the frequency and severity of Raynaud’s episodes.
What We Like
- Physician-formulated specifically for vascular health
- Organic beet root boosts protective nitric oxide
- May reduce frequency of Raynaud’s attacks
- Supports overall circulation to extremities
- Vegan and keto-friendly formulation
What Could Be Better
- Premium pricing reflects quality ingredients
- Full protective effects develop over 4-8 weeks
Bottom Line: The most comprehensive supplement for Raynaud’s, addressing vascular dysfunction at its source.
2. Snap Supplements Nitric Oxide with L-Arginine – Best Value
- Supports Oxygen Delivery & Natural Energy – Nitric Oxide plays a role in circulation and energy production, supporting healthy circulation and daily vitality. Our Nitric Oxide Booster supports natural nitric oxide levels and features ginseng root, traditionally used to promote stamina, endurance, and sustained energy—without stimulants or added sugars.
- Promotes Healthy Circulation & Cardiovascular Wellness – By supporting healthy blood flow throughout the body, our nitric oxide supplement promotes natural circulation and helps maintain heart and overall circulatory wellness. This blend helps you stay active and feel good, naturally.
- L-Arginine & L-Citrulline For Active Energy & Performance – Formulated with three forms of L-Arginine and L-Citrulline, key amino acids that help support the body’s natural nitric oxide production, this supplement promotes energy production, supports healthy immune function, and helps maintain muscle health and recovery. Because natural production may vary, supplementing with L-Arginine can help support circulation, stamina, workout endurance, and overall wellness for an active lifestyle.
- Enhance Your Wellness Routine: Ideal for fitness enthusiasts and active adults who want to support natural energy, workout recovery, and healthy circulation. Best used alongside a balanced diet, regular exercise, and your favorite gym supplements. Convenient for use at home, in the gym, or on the go.
- Quality You Can Trust: Our vitamins and supplements are crafted by health experts and manufactured in the USA with globally sourced ingredients. This supplement is non-GMO, free of major allergens, gluten-free, and manufactured in a GMP-certified facility to ensure purity, potency, and quality. It contains no gelatin, dairy, or other animal-derived substances – making it a great option for vegans & vegetarians.
This affordable L-arginine formula provides direct nitric oxide support to help counteract the excessive vasoconstriction in Raynaud’s.
L-arginine is the direct precursor to nitric oxide, and research suggests it may help reduce Raynaud’s symptoms by improving endothelial function. Combined with L-citrulline for sustained effects, this formula helps maintain better baseline circulation and may make blood vessels less reactive to cold or stress triggers.
What We Like
- Direct L-arginine conversion to protective nitric oxide
- L-citrulline extends benefits throughout the day
- Studies show promise for reducing Raynaud’s attacks
- Excellent value with 120-capsule supply
- May reduce severity and duration of episodes
What Could Be Better
- Best absorbed on empty stomach
- Some may experience mild digestive effects
Bottom Line: The best value option with research supporting its use for Raynaud’s symptom management.
3. Luma Nutrition Omega 3 Fish Oil – Best for Prevention
- Best Omega 3 Supplement: Luma Nutrition's fish oil omega 3 supplements are premium quality with an extra strength dosage. Omega 3 fish oil with 2000mg of high quality EPA & DHA Omega 3 fatty acids, all in a softgel capsule to enhance absorption for maximum benefits.
- High EPA Fish Oil: Our product is a high epa omega 3 fish oil supplement, containing 2500 mg of fish oil, far exceeding competitor's fish oil 1200 mg servings. This omega 3 fatty acid supplement is perfect for heart circulation and brain health, supports a healthy immune system, and contributes to radiant skin and hair.
- Myriad of Health Benefits: Omega-3 fatty acids are vital to maintain healthy cardiovascular and eye function. Omega 3 fish oil supports cognitive function, improving memory, focus, and overall brain health. In addition, its overall calming properties on the body can alleviate joint stiffness, enhancing long term mobility and flexibility in aging adults.
- 30 Day Supply: Each bottle of Luma Nutrition's burpless fish oil pills last for a month to maintain optimal freshness and provide strong daily support straight from nature. This all natural cardiovascular and joint support supplement makes the perfect monthly subscription for men and women. Stay in stock and save money at the same time!
- Made in the USA by Veteran-Owned Small Business: Trust in Luma Nutrition's GMP certified, USA-manufactured supplements that are 3rd party verified. As a veteran-owned brand, we prioritize quality and expert craftsmanship to assist with your health journey.
This high-potency omega-3 formula reduces inflammation and improves blood vessel flexibility to help prevent Raynaud’s attacks.
With 2000mg of EPA and DHA per serving, this fish oil provides powerful anti-inflammatory support for your vascular system. Research shows omega-3s can improve endothelial function and reduce the exaggerated vascular response characteristic of Raynaud’s syndrome, potentially decreasing attack frequency.
What We Like
- Extra-strength 2500mg formula with 2000mg EPA/DHA
- Reduces vascular inflammation linked to Raynaud’s
- Improves blood vessel flexibility and function
- Studies support use for Raynaud’s prevention
- Comprehensive cardiovascular benefits
What Could Be Better
- Works preventively rather than acutely
- Full benefits develop over 2-3 months
Bottom Line: Excellent for long-term Raynaud’s management through reduced inflammation and improved vascular health.
4. Original Raw Beet Root Powder – Best Maximum Potency
- Natural Source: Pure beet root powder with zero artificial additives or fillers. Each scoop equals one whole beetroot, providing concentrated nutrients in an easy-to-use form. Made in USA facility following strict cGMP guidelines for quality assurance.
- Athletic Support: Premium beetroot powder naturally supports an active lifestyle and provides plant-based nutrition before workouts.Our powder dissolves easily in smoothies, juices, or water for convenient pre-workout supplementation.
- Pure quality: Our beets powder is free from common allergens including soy, dairy, gluten, nuts, shellfish, and wheat. Each batch undergoes rigorous testing in our certified lab to guarantee premium quality and potency.
- Versatile usage: Premium beets supplements perfect for smoothies, juices, or baking. Mix into pre-workout drinks or add to recipes. The organic beet powder dissolves completely with no clumping, making it easy to incorporate into your daily routine.
- Superior USA Quality: Meticulously formulated and manufactured in American facilities under strict quality standards. Our best beet powder undergoes thorough lab testing to guarantee 910g of premium beetroot powder in every package.
This concentrated beet superfood provides maximum nitric oxide support for protecting against Raynaud’s attacks.
At 2 pounds of cold-pressed beet root, this powder delivers the highest concentration of natural nitrates available. These nitrates convert to nitric oxide, helping maintain dilated blood vessels that are less prone to the excessive constriction seen in Raynaud’s. Mix into smoothies for powerful daily support.
What We Like
- Highest natural nitrate concentration for nitric oxide production
- Cold-pressed processing preserves active compounds
- May reduce both frequency and severity of attacks
- Best long-term value with large 2lb size
- Supports sustained vascular protection
What Could Be Better
- Earthy beet flavor not for everyone
- Requires mixing rather than capsule convenience
Bottom Line: The most potent nitric oxide support available for serious Raynaud’s management.
5. ZEBORA CoQ10 400mg with PQQ – Best for Vascular Health
- ENHANCED COQ10 WITH PQQ: Our CoQ10 400mg, with a 120-day supply, boosts natural CoQ10 levels for heart health. Combined with PQQ, it enhances mitochondrial energy production, vital for efficient energy and optimal heart function
- HIGH BIOAVAILABILITY: ZEBORA CoQ10 is enhanced with Black Pepper Extract and Sunflower Lecithin for superior absorption and bioavailability. Black Pepper offers antioxidant benefits, while sunflower lecithin supports skin and liver health
- OPTIMAL COMBINED OMEGA-3: Every Coq10 softgel contains 60 mg of omega-3s, which are imperative to promoting heart health. Omega-3s can improve sleep quality, support the eyes, skin, and brain health. Better absorption, better taste, and no fishy burps
- BENEFITS FOR STATIN USERS: CoQ10 is crucial for producing 95% of your body's energy, but levels decline with statin use. Supplementing with CoQ10 during statin therapy helps replenish lost levels, supporting energy production and overall organ function
- NATURAL AND PURE: All our products are third-party tested and are manufactured in a cGMP-certified facility. No Artificial Flavors or Sweeteners, No Sugar, No Starch, No Gluten, No Soy, No Wheat, and Sodium-free
This advanced formula supports vascular health through cellular energy production and antioxidant protection.
CoQ10 is crucial for cellular energy in blood vessel cells, while PQQ enhances mitochondrial function. Combined with omega-3s and BioPerine for absorption, this formula supports the cellular health and energy production your blood vessels need to function properly and resist excessive constriction.
What We Like
- High-potency 400mg CoQ10 for vascular cell energy
- PQQ enhances mitochondrial function
- BioPerine dramatically improves absorption
- Omega-3s provide anti-inflammatory support
- Comprehensive cardiovascular protection
What Could Be Better
- Works gradually through cellular health improvement
- Premium pricing for quality ingredients
Bottom Line: Excellent for addressing Raynaud’s through improved vascular cellular function and energy.
6. Snap Supplements Nitric Oxide Beet Root Gummies – Best for Compliance
- Energy & Circulation Support: Powered by beet root and pomegranate juice powder—supports healthy blood flow and circulation to help maintain natural, steady energy throughout your day.
- Nitric Oxide Production: Formulated to help maintain nitric oxide levels that support vascular health, endurance, and vitality.
- Designed for Active Lifestyles: Created for men and women who want to stay active—perfect for workouts, travel, or busy workdays when balanced energy and stamina matter most.
- Convenient and Great-Tasting: Use as your daily gummy supplement—no mixing or water required. Take them at home, the office, or the gym as part of your wellness routine.
- Quality You Can Trust: This plant-based supplement is designed for people interested in clean nutrition—manufactured in the USA with globally sourced ingredients, vegan, non-GMO, gluten-free and produced in a GMP-certified facility for purity and potency.
These convenient gummies make daily nitric oxide support enjoyable, improving long-term compliance for Raynaud’s management.
Snap’s organic beet root gummies deliver circulation-boosting nitrates in a tasty format that encourages consistent daily use—crucial for managing Raynaud’s. Regular supplementation helps maintain better baseline vascular function, potentially reducing attack frequency.
What We Like
- Tasty gummy format improves daily consistency
- Organic beet root provides natural nitrates
- Easy to maintain long-term supplementation
- May help reduce cold sensitivity
- Supports overall circulation and energy
What Could Be Better
- Contains natural sugars from gummy format
- Lower concentration than powder options
Bottom Line: Best for those who struggle with pill compliance but need consistent Raynaud’s support.
7. Sugar Free Beet Root Gummies – Best Sugar-Free
- Premium Beet Root Gummies - Beet root is a powerhouse superfood packed with essential nutrients - these sugar-free beet root gummies are a delicious way to enjoy all the benefits of high quality beet root powder in a convenient, tasty gummy
- A full 60-Day Supply - With 120 gummies per bottle, our beet root gummies are a delicious strawberry flavored treat that you can easily enjoy as part of your healthy lifestyle
- Supports Healthy Natural Stamina & Energy Levels - The natural energy-boosting effects of beet root are one of the main reasons this powerful supplement is growing in popularity
- Made with the best ingredients: Formulated with coconut oil for optimal absorption
- Superior Quality Formula - Our products are manufactured in the USA in a cGMP compliant facility using only the purest, most potent, and high quality globally sourced ingredients
These sugar-free gummies provide nitric oxide support without added sugars—ideal for diabetics with Raynaud’s.
Infused with coconut oil for enhanced absorption, these gummies deliver beet root’s vascular benefits without sugar. This is particularly important since diabetes increases Raynaud’s risk, and managing blood sugar while supporting circulation is crucial.
What We Like
- No added sugar suitable for diabetics
- Coconut oil enhances nutrient absorption
- Supports circulation without glucose impact
- Convenient gummy format
- May help diabetic Raynaud’s patients safely
What Could Be Better
- Possible aftertaste from sugar alternatives
- Higher price than regular gummies
Bottom Line: Perfect for Raynaud’s patients who need to avoid added sugars while supporting circulation.
8. Circulation Support with Cayenne and Niacin – Best Warming Formula
- Cholesterol supplement - This Cholesterol support supplement contains a powerful blend of natural ingredients including Garlic, Niacin, Policosanol, Guggul, and Cayenne Pepper, known for their potential cholesterol support benefits*
- Niacin (Vitamin B3) & Garlic - Our formula, enriched with plant sterols, vitamin B3, and odorless garlic extract, is designed to help support cholesterol levels already within the normal range*
- Tryglicerides support - Our supplement is easy to incorporate into your daily routine, offering potential support for your overall wellness. Garlic and niacin, have been traditionally associated with supporting cholesterol wellness and Cayenne Pepper may help support circulation, which is an essential aspect of well-being*
- Clean label - We are committed to transparency, so what ingredients you read on the label are what you have inside your capsules. Our Garlic Cholesterol Support Capsules are non-GMO, and devoid of heavy metals, additives, or allergens*
- Made in the USA with global ingrediets - Our Beta Sitosterol Supplement is proudly manufactured in the USA in a trustworthy facility audited by the FDA and NSF for good manufacturing practices and lab-tested, free from heavy metals, allergens, or additives. TRY IT, RISK FREE! If you’re not satisfied with our product, simply contact us and we'll take care of you.
This traditional herbal formula combines warming cayenne with circulation-supporting ingredients for Raynaud’s relief.
Cayenne pepper has been used traditionally to improve peripheral circulation and warm extremities. Combined with garlic for cardiovascular support and niacin for blood vessel dilation, this formula may help reduce the severity of Raynaud’s attacks and improve baseline circulation to fingers and toes.
What We Like
- Cayenne provides warming peripheral circulation boost
- Niacin helps dilate peripheral blood vessels
- Traditional herbs with proven circulation benefits
- May reduce attack severity quickly
- Includes cardiovascular-supporting garlic
What Could Be Better
- Niacin may cause harmless flushing
- Cayenne can be strong for sensitive stomachs
Bottom Line: An excellent traditional option for warming circulation support in Raynaud’s management.
How to Choose the Best Supplement for Raynaud’s Syndrome
When selecting supplements for Raynaud’s syndrome, you’ll want to focus on those that improve nitric oxide production and reduce vascular inflammation—the two key mechanisms that can help prevent the excessive blood vessel constriction characteristic of Raynaud’s. L-arginine and beet root supplements are your primary options for boosting nitric oxide, which helps blood vessels resist the dramatic narrowing that triggers Raynaud’s attacks.
Consider the type of Raynaud’s you have when choosing supplements. Primary Raynaud’s (occurring on its own) typically responds well to circulation-boosting supplements like L-arginine or beet root. Secondary Raynaud’s (associated with autoimmune conditions like scleroderma or lupus) may benefit more from anti-inflammatory approaches like high-dose omega-3 fish oil, though circulation support remains important.
Think about your compliance and lifestyle preferences. L-arginine works quickly and shows research support for Raynaud’s, but requires empty stomach dosing for best absorption. Beet root supplements offer gentler, sustained nitric oxide support and can be taken with food. Powders provide maximum potency but require mixing, while capsules offer convenience and gummies improve long-term adherence.
Look for formulas that combine multiple beneficial ingredients if you want comprehensive support. The best options pair nitric oxide boosters with anti-inflammatory omega-3s or antioxidants like CoQ10. This multi-pronged approach addresses both the vascular dysfunction and inflammation that contribute to Raynaud’s symptoms.
Always consult your rheumatologist or vascular specialist before starting supplements for Raynaud’s, especially if you have secondary Raynaud’s or take medications for related conditions. Some supplements may interact with blood pressure medications or immunosuppressants commonly prescribed for autoimmune-related Raynaud’s.
Benefits of Raynaud’s Syndrome Supplements
Supplements for Raynaud’s syndrome work primarily by improving endothelial function—the ability of your blood vessel lining to regulate constriction and dilation properly. In Raynaud’s, this function is impaired, causing blood vessels to overreact to cold or stress by constricting excessively. Nitric oxide-boosting supplements help restore more normal vascular responses.
Research on L-arginine for Raynaud’s shows promising results, with studies demonstrating reduced attack frequency and severity in some patients. L-arginine works by providing the raw material your body needs to produce nitric oxide, which signals blood vessels to relax. This helps prevent the dramatic constriction that cuts off blood flow to fingers and toes during Raynaud’s attacks.
Omega-3 fatty acids offer complementary benefits by reducing the inflammation that can worsen vascular dysfunction in Raynaud’s. Clinical trials have shown that high-dose fish oil (over 2000mg EPA/DHA daily) can improve cold tolerance and reduce attack frequency in some Raynaud’s patients, particularly those with secondary Raynaud’s related to autoimmune conditions.
Beyond reducing attack frequency, these supplements may improve your baseline circulation between attacks. Many Raynaud’s patients report that even without attacks, their hands and feet tend to be colder than normal. Improved baseline circulation from consistent supplementation can reduce this chronic coldness and potentially decrease the severity of attacks when they do occur.
Frequently Asked Questions
What is the best supplement for Raynaud’s syndrome?
L-arginine shows the most direct research support for Raynaud’s, with studies demonstrating it can reduce attack frequency and severity. Beet root provides similar nitric oxide benefits with gentler effects. High-dose omega-3 fish oil (2000mg+ EPA/DHA) also shows promise, particularly for secondary Raynaud’s. Many experts recommend combining nitric oxide support with omega-3s for comprehensive management.
How long does it take for supplements to help Raynaud’s?
L-arginine may reduce attack frequency within 2-4 weeks, though some people notice improvements sooner. Beet root supplements typically take 4-6 weeks for noticeable benefits. Omega-3s work more gradually, with meaningful improvements often appearing after 2-3 months of consistent use. Maximum protective effects usually develop after 8-12 weeks of regular supplementation.
Can supplements cure Raynaud’s syndrome?
Supplements cannot cure Raynaud’s, but they can significantly reduce attack frequency, severity, and duration for many people. They work by improving vascular function and reducing the exaggerated response to cold or stress, but the underlying condition remains. Think of supplements as management tools rather than cures—they help control symptoms and improve quality of life but don’t eliminate the condition.
Should I take L-arginine or fish oil for Raynaud’s?
Both are beneficial, and many Raynaud’s experts recommend using them together. L-arginine directly boosts nitric oxide to improve vascular function and reduce attack frequency. Fish oil reduces inflammation and improves overall vascular health. The combination addresses Raynaud’s from multiple angles—L-arginine provides more immediate circulation support, while fish oil offers long-term vascular protection.
Can vitamin deficiencies cause Raynaud’s-like symptoms?
Vitamin B12 and iron deficiency can cause cold extremities that mimic Raynaud’s, but they don’t cause true Raynaud’s syndrome. If you have Raynaud’s symptoms, it’s worth checking B12 and iron levels, as correcting deficiencies may reduce cold sensitivity. However, true Raynaud’s involves exaggerated vascular constriction that doesn’t improve with vitamin supplementation alone—it requires circulation-specific support.
Are there any supplements I should avoid with Raynaud’s?
Avoid high-dose caffeine supplements or products with vasoconstrictors (compounds that narrow blood vessels), as these can worsen Raynaud’s. Be cautious with stimulant-containing supplements. Also avoid supplements marketed for cold tolerance that work by constricting peripheral blood vessels—these will worsen Raynaud’s. Always check ingredient lists for vasoconstrictors or stimulants.
Can I take Raynaud’s supplements if I have lupus or scleroderma?
Yes, but always consult your rheumatologist first, especially if you take immunosuppressants or other medications. Omega-3s are generally safe and may even benefit autoimmune-related Raynaud’s. L-arginine and beet root are typically safe but should be discussed with your doctor. Some supplements may interact with medications commonly used for autoimmune conditions, so medical supervision is essential.
What lifestyle changes help supplements work better for Raynaud’s?
Dress warmly in layers, especially protecting hands, feet, and head. Avoid smoking and limit caffeine, both of which constrict blood vessels. Manage stress through relaxation techniques. Exercise regularly to improve overall circulation—just warm up gradually in cold weather. Stay hydrated. Avoid sudden temperature changes. These lifestyle modifications enhance supplement effectiveness and may reduce attack frequency on their own.
