Best Supplements for Lp(a) (2026) – Top 10 Reviewed
Lipoprotein(a), or Lp(a), is a sticky particle in your blood that can increase your risk for cardiovascular disease when levels are elevated. While genetics largely determine your Lp(a) levels, certain supplements may help support healthy cardiovascular function and address related risk factors. This guide reviews the best supplements that may help you manage Lp(a) and protect your heart health.
Our Top Picks at a Glance
- Best Overall: ZEBORA CoQ10 400mg — powerful antioxidant with omega-3 support
- Best Value: Quick Absorption CoQ10 200mg — high-potency formula for heart health
- Best Premium: Designs for Health OmegAvail Hi-Po — pharmaceutical-grade omega-3 fish oil
Quick Comparison
| Product | Key Ingredients | Form | Servings | Best For |
|---|---|---|---|---|
| ZEBORA CoQ10 400mg | CoQ10 400mg, PQQ, Omega-3 | Softgels | 120 | Overall cardiovascular support |
| Quick Absorption CoQ10 200mg | CoQ10 200mg | Capsules | 120 | Budget-friendly option |
| Designs for Health OmegAvail Hi-Po | EPA/DHA Omega-3 | Softgels | 60 | Premium fish oil |
| NATURELO Vitamin D3 K2 | D3 5000 IU, K2 MK-7 | Capsules | 180 | Vascular health |
| 1MD CardioFitMD | Beet root, L-arginine | Capsules | 60 | Nitric oxide support |
| CoQ10 600mg Softgels | CoQ10 600mg, PQQ, Omega-3 | Softgels | 60 | Extra strength formula |
| DRFOSTER CoQ10 200mg | CoQ10 200mg | Softgels | 240 | Long-term supply |
| Metagenics OmegaGenics EPA 1200 | EPA 1200mg | Softgels | 60 | High EPA concentration |
1. ZEBORA CoQ10 400mg — Best Overall
- ENHANCED COQ10 WITH PQQ: Our CoQ10 400mg, with a 120-day supply, boosts natural CoQ10 levels for heart health. Combined with PQQ, it enhances mitochondrial energy production, vital for efficient energy and optimal heart function
- HIGH BIOAVAILABILITY: ZEBORA CoQ10 is enhanced with Black Pepper Extract and Sunflower Lecithin for superior absorption and bioavailability. Black Pepper offers antioxidant benefits, while sunflower lecithin supports skin and liver health
- OPTIMAL COMBINED OMEGA-3: Every Coq10 softgel contains 60 mg of omega-3s, which are imperative to promoting heart health. Omega-3s can improve sleep quality, support the eyes, skin, and brain health. Better absorption, better taste, and no fishy burps
- BENEFITS FOR STATIN USERS: CoQ10 is crucial for producing 95% of your body's energy, but levels decline with statin use. Supplementing with CoQ10 during statin therapy helps replenish lost levels, supporting energy production and overall organ function
- NATURAL AND PURE: All our products are third-party tested and are manufactured in a cGMP-certified facility. No Artificial Flavors or Sweeteners, No Sugar, No Starch, No Gluten, No Soy, No Wheat, and Sodium-free
ZEBORA CoQ10 combines three powerful heart-health nutrients in one comprehensive formula.
This supplement delivers 400mg of CoQ10 along with PQQ for mitochondrial support and omega-3 fatty acids for cardiovascular health. The combination supports energy production at the cellular level while providing antioxidant protection that may help address oxidative stress associated with elevated Lp(a). BioPerine enhances absorption for maximum effectiveness.
What We Like
- High-potency 400mg CoQ10 dose for comprehensive cardiovascular support
- Includes PQQ and omega-3s for synergistic heart health benefits
- BioPerine black pepper extract enhances nutrient absorption
- 120 servings provide excellent value for long-term use
What Could Be Better
- Softgel size may be large for some people
- Contains multiple ingredients which some prefer to take separately
Bottom Line: ZEBORA CoQ10 400mg offers a complete cardiovascular support formula that addresses multiple risk factors associated with Lp(a) elevation.
2. Quick Absorption CoQ10 200mg — Best Value
- Precision Dosage: Our CoQ10 supplement is made with high absorption and stable CoQ 10 200mg per serving from ubiquinone so you get more out of every capsule
- Why Ubiquinone: Get the most out of each dose with our CoQ10 nutritional supplements made with a more stable form in our easy to swallow capsules for even better nutrient absorption
- The Clear Difference: At Clear Formulas we believe transparency and trust are essential which is why our product is made in an FDA inspected American facility according to strict regulatory guidelines
- Made for All in Mind: We stand by our name and our formula is made without many common allergens and additives including corn, dairy, gluten, salt, or artificial preservatives and flavors
- The Choice is Clear: We believe health doesn't have to be hard - We make it simple with carefully designed supplements to support your needs whatever your age and lifestyle we've got you covered
An affordable option that delivers therapeutic doses of CoQ10 without breaking the bank.
This formula provides 200mg of CoQ10 per serving, which falls in the range commonly used in cardiovascular research. The quick-absorption formulation helps ensure your body can utilize this powerful antioxidant effectively to support heart function and cellular energy production.
What We Like
- Excellent price-to-potency ratio for budget-conscious buyers
- 200mg dose is well-researched for cardiovascular benefits
- 120 capsules provide a four-month supply
- Enhanced absorption formula for better bioavailability
What Could Be Better
- Doesn’t include additional synergistic ingredients like omega-3s
- Lower dose than some premium options
Bottom Line: Quick Absorption CoQ10 200mg delivers research-backed cardiovascular support at an accessible price point.
3. Designs for Health OmegAvail Hi-Po — Best Premium
- High Concentration, Multi-Form Fish Oils - BioGlycerides uniquely combines three different forms of fish oils for improved bioavailability and distribution to tissues. Contains 1600mg of EPA/DHA combined per serving in a 1:1 ratio.
- Sustainable Sourcing - Sourced from sustainable wild-caught anchovy, sardine, and mackerel fish from Peru and Chile.
- Digestibility Support & Minimizing Fishy Aftertaste - The addition of lipase makes it easier for your body to digest and absorb the fish oils and to help avoid a fishy aftertaste.
- Purity Assurance - The fish oil undergoes molecular distillation and filtration, ensuring it’s pure and free from pesticides, PCBs, and other contaminants.
- Clinically-Trusted Care - DFH is the #1 practitioner supplement brand recommended by functional medicine professionals and the #1 practitioner supplement brand personally trusted by functional medicine professionals.**
Pharmaceutical-grade fish oil in the superior triglyceride form for maximum cardiovascular protection.
This professional-grade omega-3 supplement provides high concentrations of EPA and DHA in the triglyceride form, which research suggests may be better absorbed than ethyl ester forms. Omega-3s help reduce inflammation and support healthy lipid profiles, both important factors when managing cardiovascular risk associated with elevated Lp(a).
What We Like
- Triglyceride form offers superior absorption compared to ethyl esters
- Pharmaceutical-grade purity ensures minimal contaminants
- Trusted by healthcare practitioners for clinical use
- High potency EPA/DHA concentration per softgel
What Could Be Better
- Premium pricing reflects pharmaceutical-grade quality
- Some may prefer combined formulas with CoQ10
Bottom Line: Designs for Health OmegAvail Hi-Po represents the gold standard in omega-3 supplementation for serious cardiovascular support.
4. NATURELO Vitamin D3 K2 — Best for Vascular Health
- BETTER TOGETHER: Vitamin D3 and K2 are perfect partners that work together to help your body absorb and use calcium properly, so that it goes into your bones -- and away from your arteries and soft tissues.*
- HEALTHY BONES & HEART: Vitamin D3 + K2 work together to support healthy bone density and healthy blood vessels for healthy circulation.* If you take calcium, adding D3 + K2 will support healthy calcium metabolism.*
- PLANT-BASED D3: Most Vitamin D3 supplements are made from lanolin secreted from sheep skin. Our vegan D-3 is completely plant-based and sustainably sourced from wild-harvested lichen.
- ACTIVE K2: Vitamin K2 as MK-7, a bioactive form of the vitamin that shows better bioavailability in humans and has well researched benefits for healthy bone building.*
- CLEAN LABEL: Made in a GMP compliant facility. Non GMO, vegetarian, vegan, and gluten free. Does NOT contain soy, dairy, yeast, eggs, nuts, caffeine, preservatives, or coloring.
Plant-based D3 and K2 combination supports arterial health and calcium metabolism.
This vegan-friendly formula provides 5000 IU of vitamin D3 from lichen along with vitamin K2 as MK-7. Vitamin K2 plays a crucial role in directing calcium away from arteries and into bones, which is particularly important since arterial calcification can worsen cardiovascular outcomes in people with elevated Lp(a).
What We Like
- Plant-based D3 from lichen suitable for vegans
- K2 as MK-7 supports healthy arterial function
- 180 capsules provide six-month supply
- Helps prevent arterial calcification
What Could Be Better
- D3 dose may be higher than needed for some individuals
- Should consult doctor if taking blood thinners due to K2 content
Bottom Line: NATURELO D3 K2 provides essential nutrients for maintaining flexible, healthy arteries.
5. 1MD CardioFitMD — Best for Nitric Oxide Support
- Comprehensive & Convenient Nutrition: CardioFitMD is the ultimate, all-in-one superfood drink with a broad-spectrum fiber and prebiotics blend, Bacillus coagulans probiotic, and 20 key letter vitamins and minerals, to provide balanced nutrition every day.*
- Broad-Spectrum Dietary Fiber: Our proprietary broad-spectrum fiber and prebiotic blend contain 29% of the recommended daily serving. With only 5% of Americans getting enough fiber, CardioFitMD helps close the ‘fiber gap’ so you can support proper digestive, heart, and whole-body health.*
- Promote Nitric Oxide Production: The production of nitric oxide, an essential neurotransmitter, slows as part of normal aging. Our potent beetroot powder provides optimum levels of nitric oxide
- Proper Stamina & Healthy Weight Management: One scoop a day can help support energy levels. With proper stamina, you can maximize your fitness routine and promote healthy weight management.*
Beet root superfood formula supports healthy blood flow and nitric oxide production.
This physician-formulated supplement combines organic beet root with complementary nutrients to support nitric oxide production. Healthy nitric oxide levels help maintain flexible blood vessels and proper circulation, which may be particularly beneficial for those managing cardiovascular risk factors like elevated Lp(a).
What We Like
- Organic beet root provides natural nitrates for NO production
- Physician-formulated with keto-friendly ingredients
- Supports healthy blood pressure and circulation
- Vegan-friendly formula
What Could Be Better
- Some may notice beet-related digestive effects initially
- Natural ingredients may cause slight urine discoloration
Bottom Line: 1MD CardioFitMD offers a natural approach to supporting vascular function through nitric oxide pathways.
6. CoQ10 600mg Softgels — Extra Strength Formula
- Extra Strength CoQ10 600mg Softgels Supplement: The ZEBORA coenzyme q10 product features an exceptionally high content of 600mg(q10). Compared with the regular dosages of coq10 100mg, coq10 200mg, coq10 300mg and coq10 400mg, clearly our coq10 600mg contains a significantly higher amount. Therefore, it suits conventional needs and better caters to those with a higher demand for coq10 content
- Optimal Combined Omega-3 & PQQ: Omega-3s can improve sleep quality, support the eyes, skin, and brain health. PQQ will increase ATP production, their combination with coq10 provides support for energy production. ZEBORA coenzyme q10 nutritional supplements added an extra 90mg Omega-3s, 10mg PQQ per serving, which are imperative to promoting heart health
- Ultra Absorption Black Pepper & Sunflower Lecithin: Ubiquinol and ubiquinone are continuously cycle-converted in the body, our COQ10 is blended with BioPerine and Sunflower Lecithin to enhance the absorption and bioavailability. Black Pepper is not only a bioavailability enhancer; it also has potent antioxidant properties. In addition, Sunflower Lecithin is safer than other sources of Lecithin as it has been shown to help with skin health and improve liver function
- Why CoQ10 is Needed: CoQ10 plays a vital role in producing 95% of the energy used by our organs. As we age, coenzyme q10 levels in the heart and body begin to naturally decline. Medications for statin drug users have been proven to reduce coq10 levels. In addition, people who exercise regularly or do physical labor, due to high physical exertion, have a high demand for cellular energy. These all affect heart and brain function
- Natural Ingredients Trusted Source: All our products are third-party tested and manufactured in a cGMP-certified facility. ZEBORA COQ10 supplement No Artificial Flavors or Sweeteners, No Preservatives, No Sugar, No Starch, No Gluten, No Soy, No Wheat, Sodium-free, Dairy-free and Non-GMO
Maximum strength CoQ10 for those needing higher therapeutic doses.
This ultra-high potency formula delivers 600mg of CoQ10 per serving along with PQQ and omega-3s. The higher dose may be beneficial for individuals with significant cardiovascular concerns or those taking statin medications, which can deplete natural CoQ10 levels.
What We Like
- Highest CoQ10 dose available for maximum support
- Includes complementary PQQ and omega-3 fatty acids
- Ideal for statin users needing CoQ10 replenishment
- Softgel format enhances absorption of fat-soluble nutrients
What Could Be Better
- Higher dose may be more than some individuals need
- Premium potency comes with higher price point
Bottom Line: CoQ10 600mg provides therapeutic-level support for comprehensive cardiovascular protection.
7. DRFOSTER CoQ10 200mg — Best Long-Term Supply
- 6× BETTER ABSORPTION CoQ10: The latest coq10 200mg softgels use a multi-ingredient formula to enhance CoQ10 bioavailability. This easily absorbed key nutrient boosts vitality, protects blood vessels, and provides cellular energy, making it essential for the body
- Cellular Energy: Coenzyme Q10 is a vitamin-like compound that is essential for cellular energy production, and PQQ helps increase mitochondrial energy cofactor levels and efficiency. This combination boosts energy levels within cells, providing the body with more energy and vitality
- High-Quality Fat Form: MCT and grape seed oil provide an easily absorbed form of fat, combined with black pepper extract, to promote the body's absorption and utilization of co q 10
- Powerful antioxidant: Vitamin E and grape seed oil are important antioxidants. When coenzyme q10 200mg is combined with vitamin E and grape seed oil, the antioxidant properties of q10 supplements are enhanced, which can effectively resist free radicals and prevent cell oxidation
- Natural Ingredients: Customer satisfaction comes first! Our coq10 200mg softgels uses the finest ingredients from the source, is manufactured in a GMP certified facility, and is third-party labs tested. Non-GMO, Gluten Free, Soy Free and Lactose Free
Economy-sized bottle provides eight months of cardiovascular support.
With 240 softgels per bottle, this formula offers exceptional value for those committed to long-term CoQ10 supplementation. The 200mg dose provides solid cardiovascular support for energy production and antioxidant protection without overwhelming your system.
What We Like
- 240-count bottle offers best value for consistent use
- 200mg therapeutic dose supported by research
- Softgel format for better absorption
- Fewer reorders needed saves time and shipping costs
What Could Be Better
- Large bottle size requires storage space
- May expire before finishing if not used regularly
Bottom Line: DRFOSTER CoQ10 200mg delivers reliable cardiovascular support with outstanding economy for long-term users.
8. Metagenics OmegaGenics EPA 1200 — High EPA Concentration
- Provides 1200 mg of EPA per serving in a high-potency, pharmaceutical-grade fish oil to support cardiovascular function, healthy triglyceride levels, and immune system health*
- Made from sustainably sourced, wild-caught cold-water fish with a burpless, enteric-coated formula for optimal absorption and no fishy aftertaste*
- Third-party tested for over 200 contaminants to ensure exceptional purity, potency, and freshness—backed by rigorous quality standards and clinical research*
- Produced in a cGMP-certified facility and Certified B Corporation; trusted by healthcare practitioners for over 40 years for safety, transparency, and results*
Professional-grade omega-3 with concentrated EPA for anti-inflammatory support.
This practitioner-trusted formula provides 1200mg of EPA per serving, the omega-3 fatty acid most associated with cardiovascular and anti-inflammatory benefits. High EPA intake may help address the inflammation and oxidative stress that can accompany elevated Lp(a) levels.
What We Like
- Very high EPA concentration for targeted cardiovascular support
- Trusted by healthcare practitioners nationwide
- Molecularly distilled for purity
- EPA-focused formula ideal for inflammation concerns
What Could Be Better
- Professional-grade pricing reflects quality standards
- May need to supplement DHA separately if desired
Bottom Line: Metagenics OmegaGenics EPA 1200 provides clinical-grade omega-3 support for comprehensive cardiovascular protection.
How to Choose the Best Lp(a) Supplement
When selecting supplements to support cardiovascular health in the context of elevated Lp(a), you’ll want to focus on ingredients that address the underlying mechanisms of cardiovascular risk rather than trying to directly lower Lp(a) itself. Here’s what to consider.
Start by understanding that Lp(a) is largely genetically determined, so supplements won’t dramatically reduce your Lp(a) number the way they might affect cholesterol. Instead, you’re looking for nutrients that support overall cardiovascular function, reduce inflammation, improve endothelial health, and provide antioxidant protection. CoQ10 is one of the most well-researched nutrients for heart health, particularly for energy production in heart muscle cells and as an antioxidant. Look for doses between 100-600mg daily depending on your needs and budget.
Omega-3 fatty acids from fish oil deserve serious consideration because they address inflammation and support healthy triglyceride levels, both relevant when managing cardiovascular risk. Choose products providing at least 1000mg combined EPA and DHA daily, and prioritize the triglyceride form over ethyl esters when possible for better absorption. If you’re vegetarian or vegan, algae-based omega-3s can provide similar benefits.
Consider vitamin K2 alongside vitamin D3 for arterial health. Vitamin K2, especially as MK-7, helps direct calcium into bones and away from arteries, which is crucial since arterial calcification can worsen cardiovascular outcomes. Look for at least 180mcg of K2 as MK-7 daily, though check with your doctor if you take blood thinners. Vitamin D3 doses typically range from 2000-5000 IU daily, but your ideal dose depends on your current vitamin D status.
Look for third-party testing certifications that verify purity and potency, especially for fish oil products where contamination with heavy metals or PCBs is a concern. Quality manufacturers will provide certificates of analysis or mention testing by organizations like USP, NSF, or IFOS. Check expiration dates and storage recommendations, as omega-3s and CoQ10 can oxidize over time, reducing their effectiveness.
Consider your overall supplement regimen and whether you prefer combination products or individual nutrients. Some people like all-in-one formulas for convenience, while others prefer customizing doses of each nutrient separately. If you take medications, especially statins or blood thinners, consult your healthcare provider before starting new supplements as interactions are possible.
Benefits of Supplements for Cardiovascular Health
Understanding how specific nutrients support heart health can help you make informed decisions about supplementation when managing cardiovascular risk factors like elevated Lp(a).
CoQ10 plays a fundamental role in cellular energy production, particularly in the heart muscle which has among the highest energy demands of any tissue in your body. This coenzyme is essential for the mitochondria to produce ATP, the energy currency that powers every heartbeat. Beyond energy production, CoQ10 acts as a powerful antioxidant, protecting cell membranes and LDL cholesterol from oxidative damage. Some research suggests CoQ10 may help maintain healthy blood pressure and support recovery in people with heart failure, though more research is needed specifically for Lp(a) management.
Omega-3 fatty acids from fish oil provide multiple cardiovascular benefits that may be particularly relevant when Lp(a) is elevated. EPA and DHA help reduce inflammation throughout the body, including in blood vessel walls where inflammation can contribute to atherosclerosis. They support healthy triglyceride levels, improve endothelial function (the health of blood vessel linings), and may reduce the risk of dangerous heart rhythm abnormalities. The anti-inflammatory effects of omega-3s may help counteract some of the pro-inflammatory effects associated with elevated Lp(a).
Vitamin K2 and D3 work synergistically to support cardiovascular health through calcium metabolism. Vitamin K2 activates proteins that help remove calcium from arterial walls and deposit it in bones where it belongs. This is important because arterial calcification makes blood vessels stiff and less able to regulate blood pressure effectively. Vitamin D3 supports immune function, helps regulate blood pressure, and may influence inflammation—all relevant factors in cardiovascular disease prevention. Together, these vitamins help maintain flexible, healthy arteries.
Nitric oxide support through ingredients like beet root helps maintain healthy blood pressure and circulation. Nitric oxide is a signaling molecule that tells blood vessels to relax and widen, improving blood flow and reducing the workload on your heart. Better circulation means oxygen and nutrients reach tissues more efficiently while waste products are removed more effectively. This improved vascular function may help compensate for some of the cardiovascular stress that can accompany elevated Lp(a) levels.
Frequently Asked Questions
Can supplements actually lower Lp(a) levels?
Unfortunately, most supplements don’t significantly lower Lp(a) levels since genetics largely determines your baseline. However, certain nutrients like niacin (vitamin B3) in high doses may modestly reduce Lp(a), though this requires medical supervision due to potential side effects. The better approach is using supplements to address other cardiovascular risk factors—reducing inflammation, supporting healthy blood pressure, maintaining flexible arteries, and protecting against oxidative stress. These strategies help minimize the cardiovascular risk associated with elevated Lp(a) even if the number itself doesn’t change dramatically.
How long does it take to see results from cardiovascular supplements?
The timeline varies depending on which biomarker you’re measuring and which supplement you’re taking. CoQ10 levels in your blood typically increase within 2-4 weeks of consistent supplementation, though you may not feel different. Omega-3s can begin affecting triglyceride levels within 4-6 weeks, with maximum benefits often seen after 3 months of regular use. For nutrients supporting blood pressure or arterial flexibility, measurable changes might take 8-12 weeks. Remember that cardiovascular health is about long-term risk reduction rather than immediate symptom relief, so patience and consistency are essential.
Should I take these supplements if my Lp(a) is normal?
If your Lp(a) is in the normal range, whether to take cardiovascular supplements depends on your overall health profile and other risk factors. CoQ10 and omega-3s offer broad health benefits beyond Lp(a) management, including support for brain function, joint health, and cellular energy production. However, if you have no cardiovascular risk factors and eat a balanced diet rich in fatty fish and antioxidant-rich foods, you may not need these supplements. Discuss your individual situation with your healthcare provider to determine whether supplementation makes sense for your specific health goals.
What’s the difference between ubiquinone and ubiquinol forms of CoQ10?
Ubiquinone is the oxidized form of CoQ10 that your body converts to ubiquinol, the active antioxidant form. Younger people typically convert ubiquinone to ubiquinol efficiently, but this conversion becomes less efficient with age, especially after 40. Ubiquinol supplements provide the already-converted form, which may be beneficial for older adults or those with absorption issues. However, ubiquinol is typically more expensive than ubiquinone. For most people under 40, standard ubiquinone works well and costs less. Those over 50 or with absorption challenges might consider paying extra for ubiquinol.
Can I take these supplements if I’m on statin medications?
Many people taking statins benefit from CoQ10 supplementation because statins can reduce your body’s natural CoQ10 production. This depletion may contribute to the muscle pain some people experience on statins. Omega-3 supplements are generally safe with statins and may provide complementary benefits. However, always inform your doctor about all supplements you take, as some combinations require monitoring. For example, high-dose omega-3s can affect bleeding time, which matters if you take blood thinners. Vitamin K2 can interact with warfarin. Your healthcare provider can help you navigate these considerations safely.
How much omega-3 should I take daily for cardiovascular benefits?
For general heart health, most research supports 1000-2000mg of combined EPA and DHA daily. If you have elevated triglycerides, your doctor might recommend higher doses of 2000-4000mg daily under medical supervision. When choosing a product, check the label for actual EPA and DHA content rather than total fish oil amount—a 1000mg fish oil capsule might contain only 300mg of EPA+DHA. If you’re vegetarian or have fish allergies, algae-based omega-3s providing at least 250-500mg of combined EPA and DHA daily can offer similar benefits, though you may need higher doses to match the effects of fish oil.
Are there any side effects I should watch for?
Most cardiovascular supplements are well-tolerated at recommended doses, but some people experience minor side effects. CoQ10 can occasionally cause digestive upset, particularly at higher doses, so starting with a lower dose and taking it with food helps. Omega-3s may cause fishy burps, loose stools, or mild digestive discomfort in some people—choosing enteric-coated capsules or keeping them in the freezer can minimize these issues. High-dose omega-3s can increase bleeding risk, so inform your doctor if you’re having surgery. Vitamin K2 should be used cautiously if you take warfarin. If you experience any unusual symptoms, discontinue use and consult your healthcare provider.
Do I need to take these supplements with food?
Yes, taking cardiovascular supplements with meals significantly improves absorption and reduces side effects. CoQ10 and omega-3s are fat-soluble, meaning they absorb much better when consumed with dietary fat—taking them with your fattiest meal of the day optimizes absorption. This also helps prevent the digestive upset some people experience with fish oil on an empty stomach. Vitamin D3 and K2 are also fat-soluble and should be taken with food. Water-soluble nutrients like vitamin C or B-complex can be taken with or without food, though some find they’re gentler on the stomach when taken with meals.
