Best Supplements for ADHD Adults (2026) – Top 10 Reviewed
Managing ADHD as an adult often requires a multifaceted approach, and supplements can play a supportive role alongside traditional treatments. Whether you’re looking to enhance focus, reduce impulsivity, or support overall brain health, the right supplement regimen can make a meaningful difference in your daily functioning and quality of life.
Our Top Picks at a Glance
- Best Overall: NATURELO Whole Food Brain Supplement – comprehensive formula with proven ingredients
- Best Value: Focus Factor Original – pharmacist-recommended with clinical backing
- Best Premium: MemoryXL Magnesium L-Threonate – advanced cognitive support
Quick Comparison
| Product | Key Ingredients | Form | Servings | Best For |
|---|---|---|---|---|
| NATURELO Whole Food Brain Supplement | Bacopa, Ginkgo, B-Complex | Capsules | 60 | Overall brain health |
| Focus Factor Original | Bacopa, Huperzine, Multivitamin | Tablets | 150 | Memory & focus |
| MemoryXL Magnesium L-Threonate | Magtein, Phosphatidylserine | Capsules | 90 | Cognitive enhancement |
| Focus Factor Extra Strength | DMAE, Bacopa, DHA | Tablets | 120 | Enhanced concentration |
| TMG Betaine Liquid Drops | Trimethylglycine 1000mg | Liquid | 60 | Methylation support |
| Focus Factor Brain Multivitamin | Beta Carotene, Bacopa | Tablets | 180 | Daily cognitive support |
| Zest Energy Tea Assortment | Caffeine, L-Theanine | Tea Bags | 40 | Alertness & calm focus |
1. NATURELO Whole Food Brain Supplement – Best Overall
- MEMORY SUPPLEMENT FOR BRAIN HEALTH: Naturelo Brain Blend is a brain health supplement for memory and focus support, assisting with recalling words and retaining facts can become more challenging with age. Naturelo formula includes BacoMind(R), a standardized Bacopa extract, which has been clinically shown to enhance memory and learning in older adults.
- FOCUS SUPPLEMENT: Naturelo cognitive health supplement helps you stay on task without the need for stimulants providing you with natural mental energy support. Naturelo stimulant-free formula features Brain berry(R), a standardized, high potency Aronia berry extract, which has been clinically shown to help support concentration and brain fitness.
- BRAIN HEALTH SUPPLEMENT: Essential vitamins like B complex and vitamin C help maintain brain health and support a healthy mood. Naturelo Brain Health vitamin formula includes high potency B12, an especially vital brain nutrient for older adults.
- BRAIN HEALTH SUPPLEMENTS FOR ADULTS: Naturelo brain support supplement contains botanicals such as lion’s mane, turmeric, blueberry, and eleuthero, which are rich in antioxidants that can cross the blood-brain barrier and protect cells against free radicals as a result of oxidative stress.
- JUST THE GOOD STUFF: Naturelo believes the best supplements come from nature, not from a lab. This plant-based supplement is non-GMO and vegan-friendly, with no preservatives, coloring, or flavoring, and no dairy or soy.
NATURELO delivers comprehensive brain support with a whole-food approach that addresses multiple aspects of ADHD symptom management.
This formula combines clinically studied ingredients like bacopa monnieri for memory enhancement, ginkgo biloba for improved circulation and focus, and a full spectrum of B-vitamins crucial for neurotransmitter production. The whole-food sourcing means better absorption and bioavailability compared to synthetic alternatives.
What We Like
- Whole food-based ingredients for superior absorption
- Comprehensive B-vitamin complex supports dopamine production
- Bacopa and ginkgo are well-researched for cognitive function
- Free from artificial additives and fillers
What Could Be Better
- Requires multiple capsules per serving
- May take several weeks to notice full effects
Bottom Line: An excellent all-around choice that supports brain health through natural, whole-food nutrients while addressing key areas affected by ADHD.
2. Focus Factor Original – Best Value
- #1 PHARMACIST RECOMMENDED MEMORY SUPPLEMENT BRAND: Focus Factor is the #1 Pharmacist Recommended Brand based on the results of the U.S. Pharmacy Times Survey of Pharmacists’ OTC Recommendations for “Memory Support” dietary supplement, 2025-2026.
- COMPLETE MULTIVITAMIN IMPROVES FOCUS: Focus Factor Extra Strength brain supplements contain a powerful combination of vitamins, minerals, and neuro-nutrients, that not only power your brain but can also replace your daily multivitamin
- CLINICALLY TESTED RESULTS: A clinical study showed that adults who took the original Focus Factor as directed for six weeks improved their memory, concentration and focus.
- PREMIUM INGREDIENTS: Focus Factor brain support supplements are enriched with a powerful combination of premium ingredients like bacopa, phosphatidylserine, DMAE, and a comprehensive blend of vitamins and minerals.
- FOCUS FACTOR: With millions of bottles sold, Focus Factor has been helping people improve their memory, concentration, and focus for nearly 20 years.
As the #1 pharmacist-recommended memory supplement brand, Focus Factor offers clinically tested results for improving concentration and focus.
Clinical studies show that adults taking Focus Factor as directed for six weeks improved memory recall and concentration. The formula includes bacopa for memory support, huperzine for acetylcholine enhancement, and a complete multivitamin that can replace your daily supplement.
What We Like
- Clinically proven to improve memory and focus
- Pharmacist-recommended brand with nearly 20 years of results
- Complete multivitamin formula saves money
- Large bottle size offers excellent value
What Could Be Better
- Contains iron, which may not be suitable for everyone
- Tablets may be large for some users
Bottom Line: A trusted, research-backed option that combines brain-boosting nutrients with complete multivitamin support at an affordable price point.
3. MemoryXL Magnesium L-Threonate – Best Premium
- WHAT IT DOES – MemoryXL is a clinically proven brain supplement that helps you Improve clarity & focus, so you stay locked in*. Sharpens attention for better learning and memory*. Perfect for students and young pros who need to perform.
- WHY IT WORKS – MemoryXL is the only stick-pack supplement that combines Magtein. (Magnesium L-Threonate) – a unique form of magnesium that crosses the blood brain barrier, Phosphatidylserine – supports brain cell structure*, and Vitamins C, D & B6 – essential for brain energy and mood.
- WAYS MEMORYXL SUPPORTS YOUR BRAIN – MemoryXL has been clinically proven to enhance the 5 key measure of learning, memory, and cognition by up to 50% after 4 weeks of daily use. This includes Short-Term Auditory Memory by up to 56% – Remember what you hear. Learning & Logic by up to 55% – Process and apply new info faster. Short-Term Visual Memory by up to 51% – Retain what you see. Recall Memory by up to 52% – Retrieve info more easily. Complex Memory by up to 46% – Connect and organize ideas.
- HOW TO USE – Tear open 1 stick pack daily and Mix the Cranberry flavor with water or the unflavored with your favorite 16oz drink. MemoryXL was designed for consumers who prefer not to swallow pills, caregivers, or those on the go. MemoryXL is proven to heighten concentration, mental acuity, and decision-making all with Zero calories and Zero sugar.*
- PERFECT FOR – Adults focused on preventing normal age-related cognitive decline. Professionals balancing family and career in need of focus and memory support. Women experiencing brain fog from natural occurring hormonal changes. College Students looking to improve memory and concentration.
MemoryXL features Magtein, a patented form of magnesium specifically designed to cross the blood-brain barrier for superior cognitive support.
This premium formula combines magnesium L-threonate with phosphatidylserine to support memory formation, focus, and cognitive processing. Research suggests this form of magnesium may be particularly effective for improving executive function and reducing hyperactivity in adults with ADHD.
What We Like
- Patented Magtein magnesium crosses the blood-brain barrier
- Phosphatidylserine supports cognitive function and stress response
- Specifically targets executive function challenges
- High-quality, research-backed ingredients
What Could Be Better
- Higher price point than basic supplements
- Results may take 4-12 weeks to fully manifest
Bottom Line: A premium investment for adults seeking advanced cognitive support with ingredients specifically chosen for memory and executive function enhancement.
4. Focus Factor Extra Strength – Enhanced Concentration
- #1 PHARMACIST RECOMMENDED MEMORY SUPPLEMENT BRAND: Focus Factor is the #1 Pharmacist Recommended Brand based on the results of the U.S. Pharmacy Times Survey of Pharmacists’ OTC Recommendations for “Memory Support” dietary supplement, 2025-2026.
- COMPLETE MULTIVITAMIN IMPROVES FOCUS: Focus Factor Extra Strength brain supplements contain a powerful combination of vitamins, minerals, and neuro-nutrients, that not only power your brain but can also replace your daily multivitamin.
- PROMOTES CONCENTRATION and MEMORY: Like other parts of your body, your brain needs proper nutrition to perform its best. This advanced formula improves and enhances memory, concentration, and your ability to focus.
- PREMIUM INGREDIENTS: Focus Factor brain support supplements are enriched with a powerful combination of premium ingredients like bacopa, ginkgo biloba, phosphatidylserine, and a comprehensive blend of vitamins and minerals.
- FOCUS FACTOR: We offer a range of products designed to help you find your focus. Focus Factor has been America’s brain health supplement brand for nearly 20 years, with formulas for the whole family.
This extra-strength formulation delivers more concentrated doses of key cognitive ingredients for adults needing maximum support.
The formula includes DMAE for neurotransmitter support, bacopa for memory, ginkgo biloba for circulation, and DHA omega-3 for brain structure. It’s designed for those who need more robust cognitive support than standard formulas provide.
What We Like
- Higher potency formula for enhanced effects
- Includes DHA omega-3 for brain health
- DMAE supports acetylcholine production
- Comprehensive vitamin and mineral blend
What Could Be Better
- May be too stimulating for some users
- Requires consistent daily use for best results
Bottom Line: An intensified version of the trusted Focus Factor formula, ideal for adults who need stronger cognitive support for managing ADHD symptoms.
5. TMG Betaine Liquid Drops – Methylation Support
- Advanced Formula & Rich Nutrition: The BBEEAAUU tmg supplements liquid drops contain 1000mg of trimethylglycine (TMG), ginkgo biloba extract, rhodiola rosea extract, erigeron breviscapus extract, red sage extract, jiaogulan extract, panax notoginseng extract, grape seed extract each 50mg and 1.3mg vitamin B6. Our TMG drops provides a truly balanced basic nutritional blend that meets your daily energy needs.
- Supporting Overall Health: Trimethylglycine supplement drops are crucial for many body functions and maintaining a healthy level, help to boost energy and endurance, supports methylation,cognitive function support. TMG liquid drops also help to support liver and kidney health, improve night and mood, and promote overall relaxation.
- Natural & Non-GMO Formula: Betaine is primarily derived from the molasses of sugar beets. Our Betaine Anhydrous liquid are made from high-quality, natural ingredients, free from artificial additives, fillers, andwel Non-GMO, ensuring you get the best nature has to offer. And our tmg liquid are 100% vegan and gluten-free, making them ideal for anyone adopting a plant-based lifestyle or with dietary restrictions.
- Convenient Liquid Form: Compared to capsules, liquid tmg supplements are favorable for their fast digestion and faster absorption, providing excellent absorption effects.This ensures maximum effectiveness with minimal dosage. Just drop 2 ml directly into your mouth, or add the liquid to water, drink, or your favorite food, savor our tmg liquid and indulge in the refreshing citrus fragrance and lusciously sweet flavors of blood orange, making it a hassle-free addition to your daily routine.
- High Quality: Each dose of TMG supplements formula is precisely proportioned to ensure the best effect of TMG drops, and each batch of products has undergone quality testing to ensure safety and effectiveness.
TMG (trimethylglycine) supports methylation pathways crucial for neurotransmitter production and cognitive function.
This liquid form offers superior absorption and allows for flexible dosing. TMG acts as a methyl donor, supporting the production of key neurotransmitters like dopamine and serotonin that are often dysregulated in ADHD.
What We Like
- High absorption liquid delivery system
- Supports methylation for neurotransmitter synthesis
- 1000mg per serving for effective dosing
- Flexible dosing based on individual needs
What Could Be Better
- Requires refrigeration after opening
- May have a distinct taste some find unpleasant
Bottom Line: An excellent add-on supplement that supports the biochemical pathways essential for optimal brain function and neurotransmitter balance.
6. Focus Factor Brain Multivitamin – Daily Cognitive Support
- #1 PHARMACIST RECOMMENDED MEMORY SUPPLEMENT BRAND - Focus Factor is the #1 Pharmacist Recommended Brand based on the results of the U.S. Pharmacy Times Survey of Pharmacists’ OTC Recommendations for “Memory Support” dietary supplement, 2025-2026.
- COMPLETE MULTIVITAMIN, IMPROVES MEMORY, CONCENTRATION AND FOCUS: Our Original formulation is clinically tested and proven to improve memory, concentration and focus.
- CLINICALLY TESTED RESULTS: A clinical study showed that adults who took the original Focus Factor as directed for six weeks improved their memory, concentration and focus. Focus Factor showed an increase in mean recall of 6.5 words compared to 4.5 word improvement for the placebo group, which indicates a significant beneficial effect on verbal-learning and short-term memory.ncentration and focus.
- NUTRITION FOR THE BRAIN: Our Focus Factor Original brain health supplement contains a powerful combination of vitamins, minerals, and neuro-nutrients that not only deliver nutrition for the brain but can also replace your daily multivitamin.
- QUALITY FORMULA: Our formula is free of artificial colorings, artificial sweeteners, high-fructose corn syrup, and only uses the best ingredients for quality and effective brain support.
This larger bottle provides extended supply of the trusted Focus Factor formula with comprehensive brain-supporting nutrients.
With 180 tablets, you get a full three-month supply of vitamins, minerals, and neuro-nutrients including beta carotene, bacopa, and huperzine. It’s both a brain supplement and complete multivitamin in one convenient formula.
What We Like
- Three-month supply offers excellent value
- Combines brain support with daily multivitamin
- Trusted brand with millions of bottles sold
- Beta carotene and antioxidants support brain health
What Could Be Better
- Large bottle may be inconvenient for travel
- Some may prefer separate multivitamin and brain supplement
Bottom Line: A convenient, cost-effective option that eliminates the need for separate supplements while providing comprehensive brain and body support.
7. Zest Energy Tea Assortment – Alertness & Calm Focus
- Clean, Crash-Free Energy for Busy Days: High caffeine tea bags with 135–150mg caffeine — as much as a strong cup of coffee — powered by natural L-theanine for focus, not jitters. The perfect energy tea to replace your second cup of coffee or fuel long Zoom days.
- Natural Focus Tea Backed by Science: Our unique caffeine + L-theanine combo delivers smooth, sustained energy and mental clarity. Trusted by over 1 million customers and voted “Top New Product” at the World Tea Expo, it’s the #1 best-selling high caffeine tea in the U.S.
- Healthier Coffee Alternative, Gentle on Your Stomach: Skip the acidity and anxiety of coffee. Zest’s high caffeine tea bags offer a cleaner caffeine boost that’s easier on digestion and non-GMO, Keto-friendly, and sugar-free — perfect for health-conscious professionals and parents alike.
- Energizing Variety Pack for Every Mood: Enjoy an energy tea assortment box of flavorful black and green breakfast teas designed for focus and performance. Ideal as morning tea or a midday recharge, each pyramid tea bag is plastic-free and individually sealed for freshness.
- More Energy, Less Crash — Naturally: Each sip fuels focus and productivity without the coffee crash. Whether you’re a focused professional, busy mom, or academic grinder, Zest helps you stay alert and calm. Includes 80 pyramid tea bags, 135–150mg caffeine, and no sugar.
This tea sampler provides natural caffeine combined with L-theanine for alert yet calm focus throughout the day.
The combination of black and green teas offers varying levels of caffeine while the natural L-theanine content promotes relaxed alertness without jitters. This can be particularly helpful for adults with ADHD who need sustained focus without overstimulation.
What We Like
- Natural caffeine from black and green tea
- L-theanine promotes calm, focused alertness
- Variety pack lets you find your preferred strength
- No artificial stimulants or additives
What Could Be Better
- Effects are temporary compared to daily supplements
- Requires brewing time and preparation
Bottom Line: A natural, gentle way to boost focus and alertness throughout the day, perfect as a complement to daily supplement regimens.
How to Choose the Best ADHD Supplement for Adults
When selecting supplements for adult ADHD, you’ll want to consider several key factors to ensure you’re choosing products that will genuinely support your needs.
Evidence-Based Ingredients: Look for supplements containing ingredients with research backing their cognitive benefits. Bacopa monnieri has been studied for memory enhancement, magnesium L-threonate for cognitive function, omega-3 fatty acids for brain structure, and B-vitamins for neurotransmitter production. The more research supporting an ingredient, the more confident you can be in its potential effectiveness.
Quality and Purity: Choose supplements from reputable manufacturers who conduct third-party testing and follow Good Manufacturing Practices (GMP). This ensures you’re getting what’s listed on the label without harmful contaminants. Look for certifications and transparency about sourcing and testing.
Comprehensive vs. Targeted Formulas: Decide whether you need a broad-spectrum supplement addressing multiple aspects of cognitive function or a targeted formula focusing on specific symptoms. Comprehensive formulas like multivitamins with added brain support can be convenient and cost-effective, while single-ingredient supplements allow you to customize your regimen based on your specific needs.
Form and Bioavailability: Consider how well your body can absorb the supplement. Liquid forms often offer superior absorption, while capsules may be more convenient. Whole-food sourced nutrients typically have better bioavailability than synthetic versions. The delivery method should fit your lifestyle and preferences.
Your Individual Response: Everyone’s biochemistry is unique, especially with ADHD. What works well for one person may not work as effectively for another. Be prepared to experiment with different supplements and dosages, keeping notes on how you feel. Give each supplement adequate time to work—typically 4-8 weeks—before deciding if it’s effective for you.
Benefits of ADHD Supplements for Adults
While supplements should never replace prescribed ADHD medications or behavioral therapies, they can provide meaningful support for many adults managing the condition.
Enhanced Focus and Attention: Many supplements support the neurotransmitter systems involved in attention and concentration. Ingredients like bacopa, ginkgo, and citicoline can help improve your ability to sustain focus on tasks, reducing the mental drift that often characterizes ADHD. This can translate to better productivity at work and improved completion of daily tasks.
Improved Working Memory: Supplements containing phosphatidylserine, magnesium L-threonate, and omega-3 fatty acids support the brain structures involved in working memory. Better working memory means you can hold and manipulate information more effectively, making it easier to follow multi-step instructions, remember conversations, and manage complex tasks.
Neurotransmitter Support: Many people with ADHD have imbalances in dopamine, norepinephrine, and other neurotransmitters. B-vitamins, amino acids like L-tyrosine, and methylation supporters like TMG can help your brain produce and regulate these crucial chemicals more effectively. This can lead to improvements in motivation, emotional regulation, and executive function.
Reduced Oxidative Stress: ADHD brains often experience higher levels of oxidative stress, which can damage brain cells over time. Antioxidant-rich supplements containing vitamins C and E, beta carotene, and plant-based compounds can help protect your brain from this damage, supporting long-term cognitive health and potentially slowing age-related decline.
Frequently Asked Questions
Can supplements replace ADHD medication for adults?
No, supplements should not replace prescribed ADHD medications without consulting your healthcare provider. While supplements can provide meaningful support for brain health and may help manage some symptoms, they typically don’t have the same level of effectiveness as prescription medications for moderate to severe ADHD. Think of supplements as complementary tools that can enhance your overall treatment plan, potentially allowing some people to use lower medication doses or manage mild symptoms without medication—but always make these decisions with professional guidance.
How long does it take for ADHD supplements to start working?
The timeline varies significantly depending on the supplement and the individual. Some ingredients like caffeine with L-theanine work within 30-60 minutes, while others like omega-3s, magnesium, and herbal extracts typically require 4-12 weeks of consistent use to show their full benefits. This is because they work by gradually improving brain structure and function rather than providing immediate symptom relief. Be patient and consistent, tracking your progress in a journal to notice subtle improvements you might otherwise miss.
Are there any side effects from ADHD supplements?
Most high-quality supplements are well-tolerated when taken as directed, but side effects can occur. Common mild effects include digestive upset, headaches, or changes in sleep patterns, particularly with stimulating ingredients taken too late in the day. Some supplements may interact with medications or other health conditions. Always start with lower doses to assess your tolerance, take supplements with food to reduce digestive issues, and consult your healthcare provider before starting any new supplement regimen, especially if you’re taking medications or have underlying health conditions.
Which nutrients are most important for adult ADHD?
Research suggests several key nutrients play crucial roles in ADHD symptom management. Omega-3 fatty acids (especially DHA and EPA) support brain structure and reduce inflammation. Magnesium helps regulate neurotransmitters and may reduce hyperactivity and improve sleep. B-vitamins are essential for neurotransmitter production and energy metabolism. Zinc supports dopamine regulation and may improve response to ADHD medications. Iron is important for dopamine synthesis, though supplementation should only occur if you’re deficient, as confirmed by blood tests.
Can I take multiple ADHD supplements together?
Yes, you can often combine supplements safely, but it’s important to avoid duplicating ingredients and exceeding recommended dosages. If you’re taking a comprehensive brain supplement that includes multiple ingredients, you may not need additional single-ingredient supplements. Be cautious about combining multiple stimulating supplements, as this can cause jitters, anxiety, or sleep problems. Work with a healthcare provider or nutritionist familiar with ADHD to create a safe, effective supplement stack tailored to your specific needs.
Should I take ADHD supplements with food?
Most supplements are better absorbed and cause fewer digestive side effects when taken with food, particularly those containing fat-soluble vitamins (A, D, E, K) or omega-3s. However, some supplements may be more effective on an empty stomach. Check the label for specific instructions. Generally, taking supplements with breakfast or lunch is ideal, as evening doses of stimulating ingredients can interfere with sleep. Consistency in timing helps maintain steady blood levels and makes it easier to remember to take them daily.
What’s the difference between children’s and adult ADHD supplements?
Adult formulations typically contain higher doses of active ingredients to account for larger body size and potentially more severe symptoms. They may also include ingredients not recommended for children, such as certain herbs or higher levels of stimulating compounds. Children’s formulas often come in chewable or gummy forms with lower dosages and flavoring. Adults should not take children’s formulas as they likely won’t provide therapeutic doses, and children should never take adult formulas without healthcare provider approval due to the risk of excessive dosing.
How do I know if my ADHD supplements are working?
Track specific symptoms before starting supplements and monitor changes over time. You might notice improvements in your ability to start and complete tasks, reduced mental fog, better organization, improved emotional regulation, or enhanced working memory. Keep a daily journal rating your symptoms on a scale of 1-10, noting any changes in work performance, relationships, or daily functioning. It’s also helpful to ask trusted friends or family members if they notice any positive changes, as we’re not always the best judges of our own improvements. Give supplements at least 4-8 weeks before evaluating effectiveness.
