Best Supplements for Intermittent Fasting (2026) – Top 10 Reviewed
Intermittent fasting has become one of the most popular approaches to weight loss and metabolic health. The right supplements can help you maximize fat burning during fasting windows, maintain energy levels, and ensure you’re getting adequate nutrition during eating windows. This guide covers the best supplements to enhance your intermittent fasting results.
Our Top Picks at a Glance
- Best Overall: GLP-1 Supplement for Women & Men — supports appetite control and fat burning
- Best Value: Keto BHB Exogenous Ketones — accelerates fat adaptation during fasting
- Best Premium: HMR Vegetarian Entrée Pack — complete nutrition for eating windows
Quick Comparison
| Product | Key Ingredients | Form | Servings | Best For |
|---|---|---|---|---|
| GLP-1 Supplement 17-in-1 | GLP-1 Activators | Capsules | 60 | Appetite control |
| GLP-1 Naturally 16X | Natural GLP-1 Support | Capsules | 60 | Natural satiety support |
| Keto BHB Exogenous Ketones | BHB Salts | Capsules | 60 | Fasting energy |
| HMR Vegetarian Entrée Pack | Complete Nutrition | Pre-packaged | Varies | Breaking fast |
| Raw Generation 5-Day Detox | Organic Juice Blend | Liquid | 5 days | Extended fasting support |
| Amino Slim BCAA | BCAAs, L-Carnitine | Powder | 30 | Muscle preservation |
| EVL Ultimate Pre Workout | Thermogenic Blend | Powder | 40 | Fasted workouts |
| Green Tea Weight Loss Pills | 45% EGCG | Capsules | 60 | Fasting fat burning |
1. GLP-1 Supplement 17-in-1 Scientific Formula — Best Overall
- Comprehensive GLP-1 Pathway Support : Our GLP-1 supplement features a powerful 5-in-1 blend system with berberine, probiotics (including Akkermansia), and natural fibers. This complete formula support for the body’s GLP-1 hormone through its production, activation, and enhancement, promoting overall metabolic wellness.
- Berberine & Akkermansia Probiotic : The synergy of Berberine and Akkermansia in our GLP-1 supplement—a foundation for healthy digestion, balanced bl**d sugar, and key metabolic pathways (AMPK/GLP-1). From Berberine, the path to smoother, more vibrant skin. Through Akkermansia, nurturance of your gut ecosystem—the cornerstone of metabolic health and a radiant glow. Support your inner health and outer glow in our delicious GLP1 Gummies.
- Enhanced Gut Health : GLP-1 Supplement featuring live anaerobic strains (Akkermansia muciniphila, Clostridium butyricum, and Bifidobacterium infantis), they are specifically designed to reach the lower intestine. Our formula promoting a balanced microbiome for optimal GLP-1 production and gut health.
- Enjoy a healthier lifestyle : Our GLP-1 supplement also contains turmeric, organic resveratrol, cinnamon, green tea, yerba mate, milk thistle, bitter melon, and more. A gentle formulation for stomach comfort, enhanced nutrient absorption, and boosted overall efficacy—all for direct support of metabolic function, the GLP-1 pathway, and your overall health.
- Zero Sugar & Natural Ingredients : Savor the natural, refreshing taste of yuzu in every gummy. Our GLP 1 gummies are completely sugar-free, with monk fruit extract providing sweetness. Perfect for maintaining a low-calorie diet without compromising taste or efficacy, they are 100% vegan, gelatin-free, non-GMO, and gluten-free. Each bottle contains 90 gummies—take 3 daily to support your journey toward a healthier lifestyle.
This comprehensive formula supports natural GLP-1 production to help control hunger, extend fasting windows, and optimize metabolic function.
GLP-1 (glucagon-like peptide-1) is a hormone that naturally regulates appetite and blood sugar. This supplement helps your body produce more GLP-1 naturally, making it easier to stick to your fasting schedule without intense hunger or cravings. The 17-ingredient formula provides comprehensive support for intermittent fasting success.
What We Like
- Supports natural GLP-1 for powerful appetite control
- Makes fasting windows more comfortable and sustainable
- Helps regulate blood sugar during eating windows
What Could Be Better
- Takes 2-3 weeks to reach full effectiveness
- Premium pricing compared to basic supplements
Bottom Line: The most advanced supplement for supporting intermittent fasting through natural hormone optimization.
2. GLP-1 Naturally 16X Scientific Formula — Best Natural Support
- 16-IN-1 NATURAL GLP-1 Supplement: Our GLP-1 Probiotic of scientifically crafted formula features a potent 16X blend. This GLP1 Supplement plays a key role in eating habits*, gut, digestive and overall health. Our GLP-1 Probiotic contains hops, eriocitrin, green tea extract, probiotics for women and men, and other ingredients that naturally great for gut health, and health goals*
- HEALTHY EATING HABITS & LIFESTYLE: Our GLP-1 probiotic contains powerful ingredients like synbiotics probiotic, cinnamon bark extract, and chromium, it great for healthier eating habits*. These GLP 1 supplement probiotics for women & men not only good for gut and digestive health but also great for healthy lifestyle and overall health*
- GUT & DIGESTIVE HEALTH: With a blend of probiotics and prebiotics, this GLP-1 probiotic works to digestive health and gut microbiome balance. Our GLP-1 probiotic contains natural ingredients like Licorice, Ginger Root, Bromelain, Aloe Vera Extract, and Magnesium good for in digestive system. A healthy gut contributes to better nutrient absorption, digestive and overall health*
- ENERGY, ANTI-AGING, GENTLE & BALANCED: Harness the power of ingredients like CQ10, Folic Acid, Vitamin B6 B12, Peppermint Powderand chromium to naturally for energy and health balance. These GLP-1 probiotic components are known for their antioxidant properties that good for youthful vitality. Our formula of GLP1 probiotic is gentle, maintain a youthful, vibrant appearance without side effects*
- SAFE & GENTLE ON GUT: Our GLP-1 probiotic formulated with scientifically backed ingredients. Better than others expensive. Easy to take, no refrigeration required, vegetarian-friendly and gentle on your gut. Take 2 capsules daily, 30 minutes before meals, with water. Our GLP 1 probiotic offers a safe and effective to your health goals solutions. With high-quality, safe ingredients, you can enjoy all the benefits of GLP-1 probiotic*
A scientifically-formulated blend that naturally activates GLP-1 pathways to reduce hunger and support healthy fasting.
This natural formula works with your body’s own systems to enhance satiety hormones and make fasting feel effortless. The 16X concentrated ingredients provide powerful support without synthetic compounds, ideal for those seeking a natural approach to intermittent fasting.
What We Like
- All-natural ingredient profile
- Scientifically-backed GLP-1 activation
- Reduces hunger without stimulants
What Could Be Better
- Effects build gradually over time
- Requires consistent daily use
Bottom Line: Perfect for those who want natural appetite support to make intermittent fasting more sustainable.
3. Keto BHB Exogenous Ketones Supplement — Best for Energy
- How it Works: Try our keto BHB capsules with our proprietary BHB salts that provide you with an alternative energy source that supports ketosis and encourages the body to use lipid reserves for fuel
- Feel the Burn: Get rid of those gimmicky products and experience cutting edge keto pills with clinically tested ingredients that help improve metabolic efficiency to help you look and feel your best
- Cutting Edge Formula: Not all keto supplements are created equal which is why we exclusively use our patented bio-identical ketones with natural caffeine for sustained energy and ketosis support
- Unrivaled Quality: Enjoy faster ketosis and keto diet guidance with free support group access to purchasers of any of our proprietary ketones supplements - it’s never been easier to get results
- The Gold Standard: We are proud to be the name behind goBHB - a bio-identical ketones compound with years of research used for kickstarting ketosis found in countless keto products on the market
Provides immediate energy during fasting windows through exogenous ketones that fuel your brain and body without breaking your fast.
When fasting, your body naturally shifts to burning fat and producing ketones for energy. This supplement accelerates the process by providing BHB ketones directly, giving you clean energy and mental clarity during fasting periods without disrupting the metabolic benefits of fasting.
What We Like
- Provides energy without breaking your fast
- Supports mental clarity during fasting
- Accelerates fat adaptation for better results
What Could Be Better
- May cause mild digestive adjustment initially
- Works best when combined with low-carb eating
Bottom Line: Essential for maintaining energy and focus during extended fasting windows.
4. HMR Vegetarian Entrée Pack — Best for Breaking Fast
- DELICIOUS & SATISFYING Weight loss never tasted so good! Enjoy three of HMR’s most popular Italian entrées with this Vegetarian Medley variety pack. Set includes 2 each of Mushroom Risotto, Pasta Fagioli, and Cheese and Basil Ravioli. With only 200 - 230 calories per entrée, you won’t need to sacrifice a mouthwatering meal for a low-cal alternative.
- FILLED WITH PROTEIN With 10 - 14 grams of protein and 3 - 7 grams of fiber per entrée, these vegetarian cuisines are tasty and filling. The 8oz servings are portion controlled to help you stay on track while pursuing your weight loss goal.
- NO REFRIGERATION REQUIRED Shelf-stable, individual servings are ideal for home, office, and travel. Maintain a healthy diet while on the go. Heat in the microwave for just one minute and enjoy.
- ADD VARIETY Pair steamed vegetables or a hearty salad to complement these entrées and further supplement their nutritional benefits. Meals shown with added vegetable suggestions. Visit our Amazon Store for more delicious entrée selections.
- ABOUT HMR HMR Plan, LLC is a weight loss/maintenance and lifestyle change program designed to provide nutritionally complete, filling meals, and snacks that are calorie and portion controlled.
Pre-portioned, nutritionally-balanced meals perfect for breaking your fast with the right nutrients and portion control.
What you eat when breaking your fast matters as much as the fast itself. These vegetarian entrées provide balanced nutrition, appropriate portions, and easy preparation, ensuring you break your fast properly without overeating or choosing nutrient-poor foods.
What We Like
- Perfectly portioned for breaking fast
- Nutritionally balanced vegetarian meals
- Eliminates guesswork about proper refeed meals
What Could Be Better
- Higher cost per meal than home cooking
- Limited flavor variety in pack
Bottom Line: Ideal for intermittent fasters who want convenient, portion-controlled meals for their eating windows.
5. Raw Generation 5-Day Detox Cleanse — Best Extended Fast Support
- LOSE WEIGHT WITH A LOWER SUGAR DETOX: Detox with less sugar to reset your body, reduce bloating and feel lighter. Drink 6 (12oz) cold-pressed green juices each day: (1) Tarte Greens, (1) Sweet Greens, (1) Lemony Greens, (1) Apple Celery, (1) Strawberry Greens, (1) Citrus Mint.
- DETOXIFY YOUR BODY: 6 cold-pressed green juices each day flood your body with nutrients and nature's best detoxifier- Chlorophyll. Flush out toxins and unwanted weight at the same time, strengthen immunity, and increase your energy levels.
- RESET YOUR DIET: Jumpstart healthier eating habits by giving your body a clean break from processed foods and refined sugar. Nutritionist-designed to cleanse your tastebuds and eliminate unhealthy cravings.
- YOU CAN EAT WITH THIS CLEANSE: No need to fear being hungry. In addition to 6 nutrient-dense juices each day, you are given a list of foods you can include during your cleanse that will not hinder results. And yes, you can keep your morning coffee.
- FLASH-FROZEN FOR CONVENIENCE & FRESHNESS: The only way to naturally preserve all raw nutrients, enzymes, and flavor. Your product will arrive frozen. Store immediately in freezer and thaw when ready to use. These ready-made juices make this cleanse sustainable for even the busiest people - Zero prep required. Last 24 hours in the fridge once thawed and up to 6 months in the freezer.
A complete 5-day juice program with 23% less sugar than competitors, designed to support extended fasting and detoxification.
For those doing longer modified fasts or wanting a structured cleanse program, this juice pack provides essential nutrients and antioxidants while keeping calorie intake low enough to maintain many fasting benefits. The reduced sugar content makes it more metabolically friendly than typical juice cleanses.
What We Like
- 23% less sugar than competing cleanses
- Complete 5-day program with all meals included
- Provides nutrients while maintaining fasting benefits
What Could Be Better
- Requires refrigeration throughout program
- Significant upfront investment
Bottom Line: Excellent for those wanting a structured, nutrient-rich approach to extended modified fasting.
6. Amino Slim Slimming BCAA Weight Loss Drink — Best Muscle Preservation
- Women's Health Supplement: Amino Slim by Raw Synergies offers a dietary supplement formulated with BCAAs, amino acids, and L-glutamine for metabolic support*
- Active Lifestyle Supplement: This muscle support supplement is crafted for non-jittery energy support that takes your workout to the next level*
- Mindful Eating Support: This nutritional supplement is formulated for women seeking support with cravings and metabolic health*
- Clean Energy Supplement: Enjoy a healthy, vegan, sugar-free supplement made with plant-based ingredients and no artificial flavors or fillers*
- Science-Backed Formula: Crafted with high-quality, research-supported ingredients, this formula is the perfect addition to your fitness routine
Preserves lean muscle during fasting with essential amino acids that support recovery without significantly impacting autophagy.
One concern with intermittent fasting is potential muscle loss. This BCAA formula provides essential amino acids to preserve muscle tissue while still allowing the metabolic benefits of fasting to occur, especially important for active individuals.
What We Like
- Preserves muscle mass during fasting
- Vegan-friendly amino acid blend
- Supports workout recovery on fasting days
What Could Be Better
- Technically breaks a pure fast (contains calories)
- Flavor may require adjustment
Bottom Line: Essential for athletes and active individuals who want to preserve muscle while practicing intermittent fasting.
7. EVL Ultimate Pre Workout Powder — Best for Fasted Exercise
- Science Based Formula - Try the ENGN Shred pre-workout energy and focus supplement with exclusive ingredients including Beta alanine Agmatine Huperzine A L-Carnitine Yohimbe CLA and much more
- Achieve More - Maximize your workouts with enhanced natural energy endurance and intense focus thanks to specially engineered blends featuring Betaine and more to amplify your performance
- Clean Complex - We’re proud to use some of the best energizing preworkout ingredients for peak performance including Forskolin and EGCG Green tea extracts to amplify your energy without the crash
- Enhanced Power and Pumps - Our tasty pre workout energy powder works as a sustainable energy source for better muscle endurance metabolic support and nitric oxide production for a shredded look
- Why Evlution Nutrition - EVL is a leading name in effective bodybuilding supplements because we take our quality seriously and only use the finest lab tested performance maximizing ingredients
Provides explosive energy and fat-burning support for working out in a fasted state without breaking your fast.
Fasted training can amplify fat burning, but you need energy to perform well. This pre-workout gives you the power to crush your workouts while fasting, with thermogenic ingredients that enhance the fat-burning benefits of training in a fasted state.
What We Like
- Provides energy for intense fasted workouts
- Thermogenic formula enhances fat burning
- Low-calorie with no significant insulin response
What Could Be Better
- Contains caffeine – avoid if fasting for sleep
- May cause tingling from beta-alanine
Bottom Line: Perfect for maximizing performance and fat burning during fasted morning workouts.
8. Green Tea Weight Loss Pills — Best Fat Burning Support
- FAT BURNER FOR MEN & WOMEN: Nobi Nutrition’s fat burners for women & men features powerfully formulated fat burning pills, with potent green tea for weight loss and belly fat burner for men and women.*
- METABOLISM & APPETITE SUPPORT: Our Green Tea fat burner is rich in catechins, compounds which support your body’s ability to burn calories.* The ingredients in these Green Tea fat burner pills work as a metabolism booster for weight loss.*
- ENERGY & FOCUS: Caffeine from Green Tea & Green Coffee Bean provides energizing, fat-burning support. These Green Tea capsules for weight loss also support clarity and focus, so you can stay sharp and focused on your fat loss goals!*
- GREEN TEA WEIGHT LOSS PILLS: The goal isn’t just to lose weight for women and men! This thermogenic fat burner for men and women contains EGCG, a compound that acts as a super antioxidant and can promote strong anti-aging properties for skin and overall health.*
- UNMATCHED QUALITY: Nobi Nutrition’s Green Tea pills fat burner supplements are Vegan, Gluten-Free, and manufactured in a facility that adheres to GMP guidelines. Each bottle of fat burners for women weight loss and men contains a 1 month supply.
High-potency green tea extract with 45% EGCG amplifies fat burning during fasting windows naturally.
Green tea extract enhances the fat-burning effects of fasting by increasing thermogenesis and fat oxidation. The high EGCG content provides powerful metabolic support without breaking your fast, making it an ideal complement to intermittent fasting protocols.
What We Like
- Natural fat burning amplification
- Standardized 45% EGCG for potency
- Supports metabolism during fasting
What Could Be Better
- Contains caffeine – time appropriately
- May cause stomach upset if taken without food
Bottom Line: Excellent for boosting the natural fat-burning benefits of intermittent fasting.
How to Choose the Best Intermittent Fasting Supplements
Selecting supplements for intermittent fasting requires understanding which products support your goals without breaking your fast.
Understand What Breaks a Fast: Technically, anything with calories can break a fast. However, the practical impact depends on your goals. For autophagy and longevity benefits, stick to zero-calorie supplements during fasting windows. For fat loss, small amounts of BHB ketones, BCAAs (under 50 calories), or fat-only supplements like MCT oil generally won’t significantly impact results. For metabolic health, avoid anything that spikes insulin.
Match Supplements to Your Fasting Schedule: Different protocols benefit from different supplements. For 16:8 intermittent fasting, appetite suppressants and energy supplements work well during morning fasts. For alternate-day fasting or extended fasts, electrolytes become crucial. For time-restricted eating focused on metabolic health, GLP-1 support and blood sugar regulators are ideal.
Prioritize Hunger Management: The biggest challenge with intermittent fasting is managing hunger during fasting windows. Supplements that support GLP-1 production, provide satiety signals, or offer zero-calorie energy (like BHB) make fasting significantly easier and more sustainable long-term.
Consider Your Activity Level: Active individuals need different support than sedentary fasters. If you exercise during fasting windows, prioritize BCAAs for muscle preservation, pre-workout supplements for energy, and electrolytes for hydration. If you’re less active, focus on appetite control and metabolic support supplements.
Support Your Eating Windows: What you consume during eating windows matters too. Consider supplements that help you make the most of your feeding periods — digestive enzymes for better nutrient absorption, protein powders to hit protein targets, or balanced meal replacements for convenient, properly-portioned refeed meals.
Benefits of Intermittent Fasting Supplements
Strategic supplementation can dramatically improve your intermittent fasting experience and results.
Enhanced Appetite Control: The hardest part of intermittent fasting is managing hunger, especially when starting. Supplements that support GLP-1 production or provide satiety signals make it much easier to extend fasting windows comfortably. This improved adherence leads to better long-term results and makes the lifestyle sustainable.
Maintained Energy Levels: Many people worry about energy crashes during fasting. Supplements like BHB ketones, MCT oil, and green tea extract provide clean energy that works with your fasted state rather than against it. This allows you to maintain productivity, focus, and physical performance even during extended fasting periods.
Preserved Muscle Mass: One legitimate concern with fasting is potential muscle loss. BCAA supplements and adequate protein during eating windows help preserve lean muscle tissue while still allowing fat loss. This is especially important for athletes or anyone doing resistance training alongside intermittent fasting.
Optimized Fat Burning: Certain supplements amplify the natural fat-burning state induced by fasting. Green tea extract, L-carnitine, and thermogenic compounds increase the rate at which your body oxidizes stored fat, leading to faster and more significant body composition changes when combined with proper fasting protocols.
Frequently Asked Questions
Will supplements break my fast?
It depends on the supplement and your fasting goals. Zero-calorie supplements like electrolytes, black coffee, or certain vitamins won’t break a fast. Small amounts of BHB ketones or MCT oil may technically provide calories but generally don’t significantly impact the metabolic benefits of fasting. BCAAs and protein supplements do provide calories and will break a strict fast, but may be acceptable if your goal is fat loss rather than autophagy. When in doubt, take supplements during your eating window.
What’s the best time to take supplements when intermittent fasting?
Timing depends on the supplement type. Appetite suppressants and GLP-1 support work best taken 30-60 minutes before your typical hunger kicks in. Energy supplements like BHB or green tea extract are ideal in the morning or before fasted workouts. Electrolytes should be taken throughout the day during fasting. Save vitamins, minerals, and any calorie-containing supplements for your eating windows to ensure proper absorption and avoid breaking your fast.
Can I exercise during fasting windows with these supplements?
Absolutely. Many people find fasted exercise particularly effective for fat burning. Supplements like BHB ketones, pre-workout formulas, and BCAAs can support exercise performance during fasting. BHB provides immediate energy, pre-workouts boost power and endurance, and BCAAs help preserve muscle. Just be aware that BCAAs technically break a fast, so if autophagy is your primary goal, stick to zero-calorie options like BHB or caffeine.
How much water should I drink while fasting?
Aim for at least 8-10 glasses of water daily while fasting, possibly more if exercising or in hot weather. Fasting naturally leads to water loss as your body depletes glycogen stores. Adequate hydration helps manage hunger, supports cellular processes, prevents headaches, and ensures your body can effectively eliminate waste products. Consider adding electrolyte supplements to your water to replace minerals lost through increased urination.
Will GLP-1 supplements help me fast longer?
Yes, GLP-1 supplements can significantly help extend fasting windows by reducing hunger and improving satiety. GLP-1 is a natural hormone that signals fullness and slows gastric emptying. Supplements that support natural GLP-1 production make it easier to fast 16, 18, or even 24 hours without intense hunger or cravings. However, they work best when combined with proper hydration and gradually extending your fasting windows over time.
Are there any supplements I should avoid while fasting?
Avoid supplements that contain significant calories, sugars, or ingredients that spike insulin during fasting windows. This includes most multivitamins with fillers, gummy supplements with sugar, protein powders, and anything labeled as a “meal replacement.” Also be cautious with fat-soluble vitamins (A, D, E, K) during fasting as they’re best absorbed with food. Save these for your eating windows.
Can intermittent fasting supplements help with stubborn fat loss?
Yes, when combined with proper fasting protocols, certain supplements can enhance fat burning. Green tea extract increases thermogenesis, L-carnitine helps transport fatty acids into cells for burning, and BHB ketones signal your body to prioritize fat metabolism. However, supplements enhance but don’t replace the fundamental metabolic shifts created by fasting itself. The biggest factors remain your fasting schedule, what you eat during eating windows, and overall calorie intake.
Should I take electrolytes while intermittent fasting?
Yes, electrolyte supplementation is highly recommended, especially for longer fasting periods or if you exercise while fasting. Fasting depletes glycogen stores, which releases water and electrolytes. Low electrolytes can cause headaches, fatigue, muscle cramps, and brain fog — symptoms often mistaken for “fasting hunger.” Supplementing with sodium, potassium, and magnesium keeps you feeling good and makes fasting much more sustainable.
