Best Supplements for Cortisol Weight Gain (2026) – Top 10 Reviewed

High cortisol levels can sabotage your weight loss efforts by promoting fat storage, particularly around your midsection. If you’re experiencing stress-related weight gain despite healthy habits, cortisol management supplements can help. This guide covers the most effective supplements for balancing cortisol levels and supporting healthy weight management.

Our Top Picks at a Glance

  • Best Overall: WellPath Soothe Hormone Balance – thyroid and cortisol support
  • Best Value: Cortisol Supplements 10-in-1 – comprehensive stress formula
  • Best Premium: WellPath Zen Stress Relief – mood and energy support

Quick Comparison

ProductKey IngredientsFormServingsBest For
WellPath Soothe Hormone BalanceAshwagandha, RhodiolaCapsules60Hormone support
Cortisol Supplements 10-in-1Ashwagandha, Magnesium, L-TheanineCapsules60Comprehensive detox
WellPath Zen Stress ReliefAshwagandha, Rhodiola, VitaminsCapsules60Mood and energy
Relaxium CalmAshwagandha, 5-HTP, MagnesiumCapsules60Stress and mood
Thyroid Support SupplementT4, T3, T2 pathway supportCapsules60Metabolism support
Soothe & Smooth Bundle GummiesMyo-Inositol, BerberineGummies60Convenient format
Prominent Nutrition SchisandraSchisandra extractCapsules60Liver and stress

1. WellPath Soothe Hormone Balance for Women – Best Overall

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WellPath Soothe Hormone Balance for Women + Cortisol Supplements for Women | Thyroid Support, Mood Support, & Metabolism Booster | Adrenal Support | Rhodiola, Selenium, Iodine | Adaptogens, 60 ct
  • [Hormone Balance for Women] Our Thyroid & Adrenal Support Supplement is formulated with rhodiola, iodine, & selenium to give the thyroid gland the nutrients it craves and needs. It helps provide hormone balance support when you need it most.
  • [Thyroid Support + Cortisol Manager] WellPath Soothe was expertly developed to include powerful, herbal ingredients that may help fight complexes like thyroid irregularities and hormone imbalances. Only 2 easy to swallow daily capsules.
  • [Effective Stress Support Formula] Our formula includes Iodine, powerful adaptogens like Ashwagandha Root extract, Selenium, Schisandra, Kelp, Eleuthero, an herb known for regulating cortisol levels, Rhodiola Rosea, L-Tyrosine, and more.
  • [Herbal Energy & Metabolism Support] Ditch that “tired and wired” feeling to support your energy levels, provide stress support, aid mental relaxation, and help improve occasional brain fog!
  • [The WellPath Promise] WellPath has been creating premium, high quality nutritional supplements since 2013. Our founders are lifelong athletes whose training taught them the power of supplements to support the body and mind.

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This comprehensive formula addresses both cortisol and thyroid function, targeting the hormonal imbalances that drive stress-related weight gain.

WellPath Soothe combines adaptogenic herbs like ashwagandha and rhodiola with thyroid-supporting nutrients to help your body manage stress more effectively. By balancing cortisol levels and supporting thyroid function, this supplement addresses two major contributors to stubborn weight gain, particularly in the midsection.

What We Like

  • Dual-action formula supports cortisol and thyroid balance
  • Helps reduce stress-related belly fat accumulation
  • Includes mood-supporting ingredients for emotional eating

What Could Be Better

  • Specifically formulated for women (men may prefer gender-neutral options)
  • Results typically require 4-6 weeks of consistent use

Bottom Line: An excellent choice for women struggling with hormonal weight gain related to stress and thyroid issues.

2. Cortisol Supplements for Women Men 10-in-1 – Best Value

B BEWORTHS Cortisol Supplements for Women Men, 10-in-1 Cortisol Detox with Ashwagandha, Magnesium, L-Theanine, Balanced Cortisol Levels, Night & Calm Support, 120 Vegan Capsules
  • Targeted Cortisol Management - Clinically formulated to help manage cortisol levels in the body, supporting a balanced cortisol response during pressure; Our cortisol detox adaptogenic blend (ashwagandha, chamomile, phosphatidylserine) works synergistically to regulate cortisol production—These cortisol supplements for women/men ideal for busy professionals, parents, or anyone seeking adrenal support without fillers or additives
  • Pressure Management & Relaxation - Are you still struggling with office pressure? Our cortisol reducer supplements blend tension-fighting ingredients like magnesium glycinate (122mg) and L-theanine (50mg) to promote relaxation while maintaining mental clarity; The addition of vitamin C (90mg) and D3 (20mcg) supports overall wellness, helping you cope with pressure naturally
  • Science-Backed Formulation - Every capsule delivers precise dosages: 250mg ashwagandha extract (20:1), 50mg chamomile (10:1), and 24mg phosphatidylserine for optimal effectiveness; Unlike generic lower cortisol for women, these cortisol supplement use no synthetic fillers—just a clean, vegan-friendly formula trusted by health-conscious users
  • Dual-Action Cortisol Balance for All Lifestyles - Whether you’re a fitness enthusiast, a night-shift worker, or juggling daily demands, our cortisol reducer adapts to your needs; St. John’s wort (20mg) and astragalus (20mg) support mood stability*, while black pepper extract (10:1) ensures maximum nutrient absorption; Take 2 capsules daily—morning and evening—for sustained cortisol support
  • 60-Day Supply - We stand behind our cortisol supplement for men and women with rigorous quality testing; Our formula is non-GMO, allergen-free, and manufactured in a cGMP facility; Join thousands who’ve transformed their tension management—try CortiCare risk-free and experience why we’re ranked among the best supplements to lower cortisol!

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This comprehensive 10-ingredient formula provides complete cortisol management support at an accessible price point.

The blend includes ashwagandha, magnesium, L-theanine, and other stress-supporting nutrients that work synergistically to help your body detox from excess cortisol. By addressing multiple pathways of stress response, this supplement helps reduce cortisol-driven cravings and fat storage while supporting better sleep and recovery.

What We Like

  • 10 active ingredients for comprehensive cortisol support
  • Includes calming nutrients like magnesium and L-theanine
  • Excellent value for multi-ingredient formula

What Could Be Better

  • Some ingredients at moderate doses to fit all 10 in one capsule
  • May require consistent use for 6-8 weeks to see full benefits

Bottom Line: A well-rounded, budget-friendly option for those seeking comprehensive cortisol management support.

3. WellPath Zen Stress Relief – Best Premium

WellPath Zen Stress Relief Supplement + Mood Support | Calm, Stress & Energy Support | Ashwagandha Root, Rhodiola Rosea, L-Theanine, Lemon Balm | Herbal Capsules, 60 Ct
  • [Stress Relief Formula] Do you get overwhelmed by daily stressors? We know the feeling! Which is why we created Zen. It's expertly curated with herbs, vitamins, and adaptogens to support your daily stressors and help you live in a zen state of mind!
  • [Stay Focused and Calm] You deserve to live a happy, healthy life. That's why we combine superfoods like Passionflower & Niacinamide powder with Riboflavin and magnesium in our products so you can be more positive throughout your day!
  • [Vitamins for Men and Women] Zen's vitamin supplement is a vegan daily multivitamin for women and men who want to help improve their mood. We use naturally sourced herbal ingredients to help cultivate a positive sense of well-being.
  • [Premium Herbal Ingredients] WellPath Zen's calming vitamin features Ashwagandha, an Ayurvedic herb known to assist with balancing occasional stress; Rhodiola Rosea, L-Theanine, Hawthorn Leaf, Lemon Balm & more! Designed for your daily stress support
  • [Featuring Ashwagandha + Rhodiola Rosea] Ashwagandha & Rhodiola Rosea are adaptogenic herbs known for their ability to help the body adapt to stress & improve energy levels.

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A premium stress relief formula that combines cortisol support with mood enhancement and sustained energy.

WellPath Zen features clinical doses of ashwagandha and rhodiola along with B vitamins to help your body adapt to stress while maintaining energy levels. This supplement addresses the fatigue and mood issues that often accompany high cortisol, making it easier to maintain healthy eating habits and stay active.

What We Like

  • Supports calm, stress relief, and sustained energy simultaneously
  • Clinical doses of key adaptogenic herbs
  • Helps prevent stress-related emotional eating

What Could Be Better

  • Premium pricing compared to basic cortisol formulas
  • May be too energizing if taken late in the day

Bottom Line: Worth the investment for comprehensive stress management with energy and mood benefits.

4. Relaxium Calm – Stress, Mood & Immune Support

Relaxium Calm - Stress, Mood + Immune Support Supplement, Non-Habit Forming with Ashwagandha, 5-HTP & GABA, Mushroom Blend. Made in USA, 60 Capsules
  • STRESS & MOOD STABILIZER: Relaxium Calm, made with Ashwagandha, uses a whole-body solution to help manage stress and promote relaxation by supplying essential vitamins for mood support and stress relief.
  • SAFE, POTENT & NON-HABIT FORMING: Doctor formulated, this calming supplement is non-habit forming, easy-to-swallow, and side-effect free. Relaxium Calm is your effective and gentle answer to relieving stress, worry and improving your mood.
  • HIGH QUALITY & PURE INGREDIENTS: Relaxium Calm is produced by one of the most pristine and experienced dietary supplement manufacturers. Cruelty Free.
  • MADE IN THE USA: Made at an FDA-inspected facility for quality you can trust, Relaxium Calm provides the perfect synergistic blend of ingredients for reliable potency and effectiveness. Our facilities use state of the art technology and adheres to strict FDA manufacturing practices.
  • 100% MONEY-BACK: We created a calm supplement that fits your life. Your satisfaction is our top priority; if we don't meet your expectations just send your stress relief supplement back for a 30-day full refund.

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A non-habit forming supplement combining stress relief with mood enhancement and immune support.

Relaxium Calm features ashwagandha, 5-HTP, and magnesium to help reduce cortisol levels while supporting serotonin production. This dual approach addresses both the physical stress response and the emotional factors that contribute to stress eating and weight gain, making it easier to stick to healthy habits.

What We Like

  • Non-habit forming formula safe for long-term use
  • 5-HTP supports mood and reduces stress-related cravings
  • Includes immune-boosting ingredients

What Could Be Better

  • Contains 5-HTP which may interact with certain medications
  • Some users may prefer single-focus cortisol formulas

Bottom Line: An excellent option for those whose cortisol-related weight gain is linked to mood and emotional eating.

5. Thyroid Support Supplement – Professional Formula

Thyroid Support Supplement for Women & Men – Professional T4, T3, T2 Triple-Pathway – Metabolism & Energy – with L-Tyrosine, Selenium, Ashwagandha & Guggul Extract – Standardized Herbs – 60 Capsules
  • Advanced Triple-Pathway Thyroid Support: Emerging research shows that supporting all three thyroid pathways is key to optimal thyroid wellness. TriThyroAxis is the first thyroid supplement scientifically designed formula to support T4 production, T3 conversion, and T2 metabolism in one. Unlike competitors that target just one pathway, TriThyroAxis support for women provides comprehensive thyroid balance for energy and metabolism.
  • Scientifically Balanced Triple-Action Formula: Our thyroid supplement combines a 1500mg formula with three specialized blends: The T4 Production Blend (organic kelp, L-tyrosine, selenium, and zinc) supports T4 production. The T3 Conversion Blend (guggul and turmeric) aids in converting T4 to active T3. The T2 Metabolic Blend (L-Thyronine, green tea extract) refines metabolism and energy, providing complete thyroid and metabolic.
  • Premium Standardized Ingredients: Thyroid support for women & Men uses professional-grade, standardized botanical extracts, each selected for their potency and effectiveness and dosed based on research to optimal dosages, providing reliable support for thyroid and metabolic. The formula is free from artificial additives, common allergens, and fillers.
  • Energy and Metabolism: Our nutritional supplements supports not just thyroid, but also energy and metabolism. With key ingredients like Magnesium and Ashwagandha, it refines metabolism and provides steady energy throughout the day. Ideal for those seeking more than basic thyroid support, our thyroid supplements supports both physical and mental energy, keeping you focused and energized.
  • TriThyroAxis Innovative Triple-Pathway Formula: TriThyroAxis is a patented formula uniquely designed to support T4 production, T3 conversion, and T2 metabolism. Its name reflects its function: "Tri" for the three thyroid pathways, "Thyro" for its thyroid hormone focus, and "Axis" for its role in endocrine balance. This advanced approach makes thyroid support a more comprehensive and effective solution compared to conventional thyroid supplements.

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A professional-grade formula targeting the thyroid-cortisol connection for improved metabolism and energy.

This supplement supports the T4, T3, and T2 pathways that are often disrupted by chronic stress and elevated cortisol. By optimizing thyroid function alongside stress management, it helps restore metabolic rate that may have slowed due to chronic cortisol elevation.

What We Like

  • Triple-pathway thyroid support (T4, T3, T2)
  • Addresses cortisol-thyroid interaction for metabolism
  • Professional-grade formulation

What Could Be Better

  • More focused on thyroid than direct cortisol reduction
  • Should consult healthcare provider if on thyroid medication

Bottom Line: Ideal for those with confirmed cortisol-related thyroid dysfunction contributing to weight gain.

6. Soothe & Smooth Bundle Gummies

Soothe & Smooth Bundle Gummies - Cortisol & Myo-Inositol Supplement with D-Chiro Inositol, Berberine, Magenesium, Ashwagandha, L-Theanine, Vitamins D3+K2 & B12, Folate, Zinc Lion's Mane (150 Gummies)
  • Complete Wellness Bundle : Simplify your routine with Parrox’s 2-in-1 set, a 13-in-1 Cortisol Support and a 16-in-1 Myo-Inositol Complex. Packed with Ashwagandha, Magnesium, L-Theanine, Berberine, and Zinc for balanced mind and body support.
  • Enhanced Absorption & Synergy – Each gummy is formulated for optimal bioavailability, combining Myo-Inositol, D-Chiro Inositol, Ashwagandha, and L-Theanine for better results than taking them separately.
  • Comprehensive Myo-Inositol Blend – Our 16-in-1 formula includes Myo-Inositol, Berberine, Chasteberry, DIM, Magnesium, and Zinc to support hormonal balance, mood, and daily vitality—all in one convenient gummy.
  • Simplify Your Supplement Routine – Replace multiple bottles with one powerful bundle. Featuring Folate, Omega-3, and Rhodiola in a delicious mixed-berry flavor to help support calm, focus, and overall well-being.
  • Clean, Quality Formula – Made in the USA in a GMP-certified facility with no artificial fillers or preservatives. Parrox gummies are crafted with ethically sourced ingredients for purity you can trust.

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A convenient gummy format combining cortisol support with metabolic ingredients.

These gummies provide myo-inositol and berberine alongside cortisol-balancing herbs. The combination addresses both stress-hormone balance and insulin sensitivity, making it particularly effective for those with stress-related metabolic dysfunction contributing to weight gain.

What We Like

  • Convenient gummy format for easy daily use
  • Combines cortisol support with metabolic ingredients
  • Pleasant taste makes consistent supplementation easier

What Could Be Better

  • Contains some sugar from gummy base
  • Lower doses per serving compared to capsule formulas

Bottom Line: A tasty, convenient option for those who struggle with swallowing capsules.

7. Prominent Nutrition Schisandra

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Prominent Nutrition Schisandra - Supplement for Liver & Stress Support - No Artificial Colors - Non-GMO, Vegan & Gluten-Free - 60 Capsules (60 Servings)
  • Daily Schisandra Supplement: Schisandra delivers 500 mg of pure schisandra fruit berry extract for stress management support*
  • Liver Support Formula: This adaptogenic supplement offers natural stress and menopause symptoms support, while supporting liver function for your overall wellness*
  • Daily Stress Support: For natural resilience to everyday stress, take one capsule twice daily or as recommended by your healthcare professional*
  • Non-GMO & Vegan Supplement: This health supplement contains no artificial colors and is non-GMO, vegan, gluten-free, dairy-free, and soy-free
  • Quality You Can Trust: Prominent Nutrition delivers pure, researched ingredients crafted in NSF-certified facilities with rigorous testing for potency and transparency

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A focused schisandra formula supporting liver function and stress response.

Schisandra is a powerful adaptogen that helps your body manage stress while supporting liver health – crucial for processing excess cortisol. This single-ingredient approach allows for targeted cortisol management while supporting the organ systems responsible for hormone metabolism.

What We Like

  • Pure schisandra extract for targeted benefits
  • Supports both stress response and liver health
  • No artificial colors or unnecessary ingredients

What Could Be Better

  • Single-ingredient formula may need to be combined with others
  • Effects are more subtle than multi-ingredient blends

Bottom Line: An excellent addition to a cortisol management protocol, especially for liver support.

How to Choose the Best Cortisol Weight Gain Supplement

When selecting a supplement to manage cortisol-related weight gain, look for adaptogenic herbs as the foundation. Ashwagandha is the most researched, with studies showing it can reduce cortisol levels by up to 30% while lowering stress and anxiety. Rhodiola rosea is another powerful adaptogen that helps your body respond more effectively to stress while supporting energy and mental performance.

Consider formulas that address both cortisol and its downstream effects. High cortisol often disrupts thyroid function, blood sugar regulation, and sleep quality – all of which contribute to weight gain. Comprehensive formulas that include thyroid-supporting nutrients, blood sugar stabilizers, and calming ingredients like magnesium and L-theanine provide more complete support.

Look for products that support healthy cortisol rhythm rather than simply suppressing cortisol. Your body needs cortisol for normal function – the problem is chronic elevation or disrupted patterns. Quality supplements help restore natural cortisol rhythms, with levels appropriately higher in the morning and lower at night.

Quality and dosing matter significantly. Choose supplements from reputable manufacturers using standardized extracts with clinically researched doses. For ashwagandha, look for 300-600mg of KSM-66 or similar standardized extract. Avoid products with proprietary blends that don’t disclose individual ingredient amounts.

Consider timing and consistency. Cortisol-balancing supplements work best when taken consistently over several weeks. Most people see initial benefits within 2-4 weeks, with optimal results at 8-12 weeks. Take adaptogens in the morning or early afternoon to support healthy cortisol rhythm without interfering with evening relaxation.

Benefits of Cortisol Management for Weight Loss

Managing cortisol levels offers profound benefits for weight loss, particularly for stubborn midsection fat. High cortisol triggers your body to store fat preferentially in the abdominal area through multiple mechanisms. It increases insulin resistance, promotes breakdown of muscle tissue for glucose, and directly signals fat cells to store more triglycerides. By normalizing cortisol, you remove this metabolic barrier to fat loss.

Cortisol management improves your appetite regulation and reduces cravings for high-calorie comfort foods. Elevated cortisol increases levels of neuropeptide Y, a brain chemical that triggers cravings for carbohydrates and fatty foods. It also interferes with leptin signaling, making you feel hungrier even when you’ve eaten adequate calories. Balancing cortisol helps restore normal appetite signals.

Better stress hormone balance supports quality sleep, which is crucial for weight management. High nighttime cortisol disrupts sleep architecture, reducing deep sleep and growth hormone production. Poor sleep increases ghrelin (hunger hormone) while decreasing leptin (satiety hormone), making weight loss much more difficult. Normalizing cortisol rhythm improves sleep quality and hormonal balance.

Cortisol reduction enhances your exercise results by supporting muscle recovery and reducing inflammation. Chronically elevated cortisol breaks down muscle tissue and impairs recovery after workouts. By managing cortisol levels, you preserve and build lean muscle mass more effectively, which increases your metabolic rate and improves body composition.

Frequently Asked Questions

How long does it take to see weight loss from cortisol supplements?

Most people notice reduced stress-related cravings within 2-3 weeks of consistent use. Measurable changes in weight and body composition typically appear after 6-8 weeks as cortisol levels normalize and metabolic function improves. The most significant results usually occur between 8-12 weeks when combined with healthy eating and regular exercise.

Can cortisol supplements help with belly fat specifically?

Yes, because elevated cortisol preferentially promotes fat storage in the abdominal area through specific receptors in visceral fat tissue. As cortisol levels normalize with supplementation, this targeted fat storage mechanism reduces, often leading to noticeable decreases in waist circumference before overall weight changes significantly.

Are there side effects from cortisol-lowering supplements?

Adaptogenic herbs like ashwagandha and rhodiola are generally well-tolerated with minimal side effects. Some people experience mild digestive upset initially, which usually resolves within a few days. Rarely, adaptogens may cause drowsiness or mild headaches. Start with lower doses and gradually increase to minimize any adjustment period.

Can I take cortisol supplements if I’m on other medications?

Consult your healthcare provider before starting cortisol supplements if you’re taking medications, particularly thyroid hormones, blood pressure medications, or antidepressants. Some adaptogenic herbs can interact with these medications, requiring dosage adjustments or timing considerations to ensure safety and effectiveness.

Will my cortisol levels stay balanced after I stop taking supplements?

Supplements help restore balance, but long-term maintenance requires addressing the underlying stress sources. If you’ve implemented stress management techniques, improved sleep habits, and maintained healthy lifestyle changes while supplementing, you’re more likely to maintain balanced cortisol levels after discontinuing supplements.

Should I take cortisol supplements in the morning or evening?

Most cortisol-balancing adaptogens work best when taken in the morning or early afternoon to support healthy cortisol rhythm. Taking them too late may interfere with the natural evening cortisol decline needed for quality sleep. If a formula includes relaxing ingredients like magnesium or L-theanine, follow the manufacturer’s timing recommendations.

Can stress alone cause significant weight gain even with a good diet?

Yes, chronic stress and elevated cortisol can cause weight gain even when dietary intake remains consistent. Cortisol alters metabolism, increases insulin resistance, promotes muscle breakdown, and triggers cravings for high-calorie foods. This explains why some people gain weight during stressful periods despite not significantly changing their eating habits.

Do I need to change my diet while taking cortisol supplements?

While not required, reducing refined carbohydrates and increasing protein intake enhances the effectiveness of cortisol supplements. High-sugar foods cause blood sugar spikes that trigger additional cortisol release, working against your supplements. A balanced diet with adequate protein helps stabilize blood sugar and supports the supplements’ stress-management benefits.

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