Best Supplements for Glaucoma (2026) – Top 10 Reviewed
Glaucoma is a group of eye conditions that damage the optic nerve, often due to elevated intraocular pressure. While medical treatments and surgery remain the primary approaches for managing glaucoma, certain supplements may provide complementary support for eye pressure regulation, optic nerve health, and neuroprotection. This guide examines supplements with research supporting their potential benefits for glaucoma, though it’s essential to use them alongside—not instead of—prescribed treatments.
Our Top Picks at a Glance
- Best Overall: Natures Craft Eye Pressure Support — multi-ingredient formula
- Best Value: Zazzee Bilberry Extract — circulation support
- Best Premium: ScienceBased Health HydroEye — omega-3 neuroprotection
Quick Comparison
| Product | Key Ingredients | Form | Servings | Best For |
|---|---|---|---|---|
| Natures Craft | Bilberry, Saffron, Ginkgo, Niacin | Capsules | 30 | Pressure support |
| Zazzee Bilberry | Bilberry 20:1 Extract | Capsules | 120 | Circulation |
| HydroEye | GLA, Omega-3, Vitamin C | Softgels | 120 | Omega-3 support |
| Provision AREDS 2 | Lutein, Zeaxanthin, C, E, Zinc | Capsules | 60 | Antioxidants |
| Astaxanthin 10mg | Astaxanthin 10mg | Capsules | 180 | Neuroprotection |
| AREDS 2 Select | Lutein 25mg, Zeaxanthin 5mg | Capsules | 60 | High-dose support |
| Pure Encapsulations | Lutein 10mg, Zeaxanthin 2mg | Capsules | 120 | Clean formula |
| 1MD VisionMD | OptiLut Lutein | Softgels | 30 | Vision support |
1. Natures Craft Eye Pressure Support — Best Overall
- Advanced Eye Pressure Supplement - Not all eye support supplements are created equally and we feature some of the most studied eye health vitamins for adults over 50 to provide fast & lasting relief
- Bilberry Supplement for Eyes - Bilberry extract for eyes is at the heart of our eye vitamins for seniors because this unique antioxidant is packed with protective and restorative nutrients
- What's Inside - Besides for bilberry extract our vision supplement for adults is made with Niacin Ginkgo leaf Black currant extract and saffron flower extract which work together to provide comfort
- Uncompromising Quality - Choose Natures Craft and opt for a trusted brand in a wide range of vitamins for eye health for adults and kids and help combat many common concerns of eyes and vision
- Natures Craft Quality - We are proud to be a leading name a variety of wellness supplements because we know how important our eye health is and how amazing these beneficial eye health vitamins are
Natures Craft combines bilberry, saffron, ginkgo biloba, and niacin in a formula designed to support healthy ocular pressure and circulation.
This comprehensive formula includes several ingredients with research supporting their potential benefits for glaucoma. Bilberry extract provides anthocyanins that support microcirculation to the optic nerve. Ginkgo biloba has been studied for improving blood flow to the eye. Saffron shows emerging research for retinal protection. The niacin supports overall vascular health. While not a replacement for prescription treatments, this combination addresses multiple factors relevant to glaucoma.
What We Like
- Multiple ingredients targeting pressure and circulation
- Ginkgo biloba with glaucoma-specific research
- Vegan capsule formula
What Could Be Better
- Not validated as primary glaucoma treatment
- Ginkgo may interact with blood thinners
Bottom Line: Comprehensive botanical approach to supporting eye pressure and optic nerve health alongside medical treatment.
2. Zazzee USDA Organic Bilberry Extract — Best Value
- OUTSTANDING VALUE: Our Certified Organic Bilberry Extract contains 6000 mg strength per capsule, 120 capsules per bottle, AND is USDA Certified Organic – an amazing value! A single bottle contains a 4 month supply. Compare this to other leading brands that require 2 capsules per serving, contain less than 120 capsules, are not organic, and use a much less potent, non-extract powder. Our Certified Organic Bilberry Extract is a bargain not be found elsewhere!
- USDA CERTIFIED ORGANIC: Any Bilberry that is not CERTIFIED organic can be highly contaminated and even harmful. With Zazzee Naturals Certified Organic Bilberry, you can be sure your Bilberry is organic, all-natural, vegan, and non-GMO. More, while other competing products use various chemicals as fillers, binders, and excipients, our Organic Bilberry instead uses a unique blend of organic stabilizers.
- 6000 MG STRENGTH / POTENT 20:1 EXTRACT: Each capsule contains 6000 mg strength of Bilberry Extract from a potent, powerful 20:1 extract. Combine that with USDA Organic Certification, and our Extra Strength Organic Bilberry Extract is one of the strongest dosages available!
- NATURAL, VEGAN & NON-GMO: All ingredients, including the capsule, are 100% vegan. Our Extra Strength Bilberry Extract does not contain any sweeteners, artificial flavors, wheat, corn, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients. Enjoy the amazing benefits of our potent Bilberry Extract without worrying about what else might be hiding in each capsule!
- GOLD STANDARD PRODUCTION: Your health and safety mean everything to us. For that reason, our Extra Strength Bilberry Extract is manufactured in the USA, in a fully certified facility with adherence to good manufacturing policies and under the most stringent quality control. You can rest assured that you get the best value for your money!
This high-potency bilberry extract supports microcirculation to the optic nerve and retina, which may benefit glaucoma patients.
Bilberry’s anthocyanins strengthen capillary walls and improve blood flow to ocular tissues. In glaucoma, maintaining adequate blood supply to the optic nerve is crucial for preserving nerve cells. The 20:1 extract concentration delivers 6000mg equivalent strength per capsule. The USDA organic certification ensures purity, and the 4-month supply provides excellent value for long-term use.
What We Like
- Supports microcirculation to optic nerve
- High-potency 20:1 concentration
- USDA organic with 4-month supply
What Could Be Better
- Evidence mostly from European studies
- Effects on circulation develop gradually
Bottom Line: Affordable, high-quality bilberry supplement that supports ocular blood flow important for glaucoma management.
3. ScienceBased Health HydroEye — Best Omega-3 Support
- WORKS FROM THE INSIDE OUT: Nourishes the eye to support all three layers of the tear film
- CLINICALLY Tested: Shown to promote eye comfort and support a healthy ocular surface in a peer-reviewed clinical trial published in Cornea
- PROPRIETARY, BALANCED FORMULA: Precise blend of GLA, omega-3 EPA & DHA, and other key nutrients work together to help soothe dry eyes and support visual health
- FEATURES GLA – THE DRY EYE OMEGA: Provides a unique source of GLA from black currant seed oil—not found in fish or flaxseed oils—supported by multiple clinical studies for its role in dry eye
- FOR BEST RESULTS: Take four softgels daily; allow 30–60 days of consistent use to experience the full benefit, and continue daily for ongoing support
HydroEye provides omega-3 fatty acids that may offer neuroprotective benefits for the optic nerve in glaucoma.
This clinically tested formula combines GLA and omega-3 fatty acids with vitamin C for comprehensive eye support. Research suggests omega-3s may help protect retinal ganglion cells and the optic nerve from damage. The anti-inflammatory properties of EPA and DHA may also benefit glaucoma by reducing inflammatory factors. The formula addresses both neuroprotection and common dry eye symptoms in glaucoma patients.
What We Like
- Omega-3s provide neuroprotective benefits
- Anti-inflammatory effects may help glaucoma
- Clinically tested formula
What Could Be Better
- Not specifically studied for glaucoma
- Requires 4 softgels daily
Bottom Line: Excellent omega-3 source that supports optic nerve health while addressing dry eye common in glaucoma patients.
4. Provision AREDS 2 Eye Vitamins — Best Antioxidant Protection
- Professional Grade Eye Supplement - A doctor-formulated vision eye supplement based on well known AREDS 2 study. This vision supplement includes Lutein, Zeaxanthin, and other eye health vitamins in veggie caps for great eye health support.
- The Provision Difference - Our eye vitamins for vision is a custom formula designed to support your eye health.
- Eye Vitamins for Vision - Our lutein Zeaxanthin vision complex supplement is a high-quality eye vitamin that can help support your vision. Our formula helps support your healthy eyes.
- VCaps Plus Premium Vegetarian Capsules - Our vision vitamin has AREDS 2 research components like Lutein, Zeaxanthin, Zinc, Copper, Vitamin E, and Vitamin C. Our enhanced vision supplement is made with premium ingredients with no unnecessary binders.
- Trusted for over 20 years - Made in the USA in an FDA registered facility, Visivite has been a trusted supplier of Doctor formulated Eye Vitamins for more than 20 years.
Provision AREDS 2 provides comprehensive antioxidant support that may help protect the optic nerve from oxidative stress in glaucoma.
While developed for macular degeneration, this formula’s antioxidants may benefit glaucoma through neuroprotection. The high doses of vitamins C and E, along with zinc, support antioxidant defenses in the optic nerve and retina. Lutein and zeaxanthin provide additional protection. Oxidative stress contributes to retinal ganglion cell death in glaucoma, making antioxidant support a logical adjunct to pressure-lowering treatments.
What We Like
- Comprehensive antioxidant profile
- Supports optic nerve health
- Clinically validated formula
What Could Be Better
- Not specifically tested for glaucoma
- High zinc may cause stomach upset
Bottom Line: Robust antioxidant support that addresses oxidative stress component of glaucoma damage.
5. Algae Based Astaxanthin 10mg — Best Neuroprotection
- Precision Dosage: Our astaxanthin supplements are made with a carefully dosed 10mg serving and include natural vitamin E and soybean oil to enhance absorption so you get more out of every softgel
- Made from Microalgae: We make our astaxanthin nutritional supplements with a remarkable freshwater green algae called Haematococcus Pulvialis packed with beneficial compounds including carotenoids
- The Clear Difference: At Clear Formulas we believe transparency and trust are essential which is why our product is made in an FDA inspected American facility according to strict regulatory guidelines
- Made for All in Mind: We stand by our name and our formula is made without many common allergens and additives including corn, dairy, gluten, silicon dioxide and artificial preservatives
- The Choice is Clear: We believe health doesn't have to be hard - We make it simple with carefully designed supplements to support your needs whatever your age and lifestyle we've got you covered
This powerful astaxanthin supplement crosses the blood-retinal barrier to protect retinal ganglion cells affected by glaucoma.
Astaxanthin has unique neuroprotective properties that may benefit glaucoma. It can cross into retinal tissues and protect nerve cells from oxidative damage and apoptosis. Some research suggests astaxanthin may help preserve retinal ganglion cells even when eye pressure remains elevated. The 10mg dose provides clinically relevant amounts, and the 6-month supply makes it economical for long-term use.
What We Like
- Crosses blood-retinal barrier for direct protection
- May protect retinal ganglion cells
- Powerful neuroprotective antioxidant
What Could Be Better
- Human glaucoma studies are limited
- Works gradually over weeks
Bottom Line: Promising neuroprotective supplement that may help preserve optic nerve function in glaucoma.
6. AREDS 2 Select Eye Vitamins — Best High-Dose Support
- Premium Macular Health Formula - Finally, a doctor-formulated macular eye supplement based on well known AREDS 2 study. This eye supplement includes Lutein, Zeaxanthin, and other eye health vitamins in veggie caps for maximum eye health support.
- Eye Vitamins for Macular Support - Our Lutein eye supplement macular is a custom formula designed to support your eye health as your age. This premium eye supplement macular formula is vegan-safe.
- Vitamins for Eye Health - Our macular supplements are high-quality eye vitamins that can help support your vision. Our lutein and zeaxanthin based formula helps keep your eyes at their maximum health.
- VCaps Plus Premium Vegetarian Capsules - Our eye vitamin has AREDS 2 research components like Lutein, Zeaxanthin, Zinc, Copper, Vitamin E and, Vitamin C. Our eye supplement is made of carefully selected premium ingredients with no unnecessary binders.
- Trusted for over 20 years - Made in the USA in an FDA registered facility, Visivite has been a trusted supplier of Doctor formulated Eye Vitamins for more than 20 years.
AREDS 2 Select provides enhanced antioxidant protection that may benefit optic nerve health in glaucoma patients.
With high doses of lutein (25mg) and zeaxanthin (5mg) plus complete vitamin and mineral support, this formula delivers robust antioxidant protection. While not specifically studied for glaucoma, the comprehensive antioxidant profile addresses oxidative stress that contributes to optic nerve damage. The formula may be particularly beneficial for patients with both glaucoma and macular degeneration.
What We Like
- High-dose antioxidant support
- May protect against oxidative nerve damage
- Complete vitamin and mineral profile
What Could Be Better
- No specific glaucoma research
- Higher cost than basic formulas
Bottom Line: Maximum antioxidant protection for patients with glaucoma who want comprehensive eye health support.
7. Pure Encapsulations Lutein & Zeaxanthin — Best Clean Formula
- Eye Health: Pure Encapsulations Lutein/Zeaxanthin is an eye vision supplement that supports optical lens and retina health, making it ideal for eye health*
- Antioxidant Support: Zeaxanthin plus lutein help maintain the macular pigment's integrity, supporting overall vision function*
- Vegan-Friendly: Made with high-quality vegan ingredients backed by science, Pure Encapsulations Lutein/Zeaxanthin supplement is ideal for maintaining photoreceptor health and color vision*
- Suggested Use: As a dietary supplement, take 1 eye support supplement capsule daily, with a meal
- Pure Difference: What we leave out matters, too; Pure Encapsulations products are FREE FROM common allergens, artificial or unnecessary ingredients, and GMOs
Pure Encapsulations provides clean, allergen-free carotenoids that support retinal health in glaucoma.
This hypoallergenic formula delivers FloraGlo lutein and zeaxanthin without additives or common allergens. While primarily studied for macular health, these carotenoids may benefit glaucoma through antioxidant and anti-inflammatory effects. The clean formulation is ideal for people with sensitivities who need basic carotenoid support.
What We Like
- FloraGlo lutein with research backing
- Free from all major allergens
- 4-month supply provides value
What Could Be Better
- Lacks other beneficial nutrients
- No specific glaucoma studies
Bottom Line: Clean carotenoid supplement for glaucoma patients with allergies or sensitivities.
8. 1MD Nutrition VisionMD — Best Premium Vision Support
- AREDS 2-Based Formula : With 3 patented ingredients consisting of lycopene, mixed carotenes, and lutein with zeaxanthin, as well as protective vitamin E and astaxanthin, VisionMD uses the results of the groundbreaking National Eye Institute study on eye health and subsequent research to create a complete eye supplement.
- Promote Healthy Eye Function: Thanks to Lyc-O-Mato lycopene, EVTene mixed carotenes, and OptiLut with lutein and zeaxanthin, the advanced VisionMD formula offers a complete eye health supplement to help you stay sharp both now and later.
- Reduce Eye Strain and Fatigue: Blue light–the type of light generated by smartphones, e-readers, laptops, and other high-tech devices–can cause your eyes to get tired and even disrupt sleep. Potent antioxidants called carotenoids contained in the VisionMD formula can help support the eye’s natural defenses from blue light issues.±
- Encourage Long-Term Eye Health: Antioxidants help reduce oxidative damage to cells in the cone and rods in the eye. This in turn helps improve long-term eye health.§
- Improve Visual Acuity: Blurry vision can be the result of age-related eye health issues or simply tired eyes. With multiple nutrients shown to improve sharpness, long-term eye health, and eye stamina, VisionMD can help keep your future in focus.±§
VisionMD features OptiLut lutein for overall vision health support that may benefit glaucoma patients.
This doctor-formulated supplement uses clinically studied OptiLut lutein for superior absorption. While not specifically designed for glaucoma, the antioxidant support may help protect retinal tissues. The convenient once-daily dosing makes it easy to incorporate into a glaucoma treatment regimen. The formula supports everyday eye health alongside prescription medications.
What We Like
- OptiLut technology for enhanced absorption
- Once-daily convenience
- Doctor-formulated quality
What Could Be Better
- General eye support, not glaucoma-specific
- Premium pricing
Bottom Line: Quality vision supplement that provides antioxidant support for comprehensive eye health in glaucoma.
How to Choose the Best Glaucoma Supplement
First and most importantly, supplements should never replace prescribed glaucoma medications or treatments. Glaucoma requires medical management to control eye pressure and prevent optic nerve damage. Supplements can only serve as complementary support alongside your ophthalmologist’s treatment plan. Always inform your doctor about any supplements you’re taking, as some may interact with glaucoma medications or affect intraocular pressure.
Ginkgo biloba has the most research specifically related to glaucoma. Several studies suggest it may improve ocular blood flow and potentially help preserve visual field in glaucoma patients. However, ginkgo can interact with blood thinners and may increase bleeding risk, so medical clearance is essential. If your doctor approves ginkgo, look for standardized extracts containing 24% flavone glycosides and 6% terpene lactones at doses of 120-240mg daily.
Omega-3 fatty acids show promise for neuroprotection in glaucoma. Some research suggests EPA and DHA may help protect retinal ganglion cells from damage and reduce inflammatory factors involved in glaucoma progression. Fish oil supplements providing 1-2 grams of combined EPA and DHA daily appear safe and may offer additional benefits for heart and brain health as well.
Antioxidants may help counter oxidative stress that contributes to optic nerve damage in glaucoma. Vitamins C and E, along with carotenoids like lutein and zeaxanthin, provide antioxidant support for retinal tissues. While not proven to lower eye pressure, they may help protect surviving nerve fibers. The AREDS 2 formula provides comprehensive antioxidant support that may benefit glaucoma patients, especially those with concurrent macular degeneration.
Be extremely cautious about supplements claiming to cure glaucoma or replace medical treatment. No supplement can cure glaucoma or reverse optic nerve damage. Any product making these claims is misleading and potentially dangerous. Stick with well-researched ingredients that have published studies, and view supplements as potential adjuncts to proven medical therapies, not alternatives.
Benefits of Glaucoma Support Supplements
Supplements may support ocular blood flow, which is crucial for optic nerve health in glaucoma. Bilberry and ginkgo biloba contain compounds that strengthen capillaries and improve microcirculation. Since the optic nerve depends on adequate blood supply to function properly, supporting healthy circulation may help preserve nerve cells. Some research suggests that impaired blood flow to the optic nerve, independent of eye pressure, contributes to glaucoma damage.
Antioxidant supplements may help protect retinal ganglion cells from oxidative stress. These nerve cells, which make up the optic nerve, are particularly vulnerable to damage from reactive oxygen species. Oxidative stress appears to play a role in glaucoma progression even when eye pressure is controlled. Antioxidants like vitamins C and E, astaxanthin, and carotenoids may help neutralize harmful free radicals and protect surviving nerve cells.
Omega-3 fatty acids provide neuroprotective and anti-inflammatory benefits that may help in glaucoma. DHA is a major structural component of retinal cell membranes, while EPA produces anti-inflammatory compounds that may reduce inflammatory damage to the optic nerve. Some animal studies suggest omega-3s can help preserve retinal ganglion cells under pressure stress, though human studies are still limited.
Supporting mitochondrial function may benefit glaucoma since retinal ganglion cells have high energy demands. Some researchers believe mitochondrial dysfunction contributes to nerve cell death in glaucoma. Nutrients like CoQ10, alpha-lipoic acid, and B vitamins support mitochondrial health and energy production. While research is early, maintaining healthy mitochondrial function may help nerve cells survive stress from elevated pressure or poor circulation.
Frequently Asked Questions
Can supplements lower my eye pressure?
There is no reliable evidence that dietary supplements can significantly lower intraocular pressure. Some substances have shown modest pressure-lowering effects in small studies, but these haven’t been validated in large trials. Prescription medications remain far more effective for controlling eye pressure. Never stop or reduce glaucoma medications based on supplement use.
Should I take supplements if my glaucoma is well-controlled?
Even with well-controlled eye pressure, glaucoma can still progress through mechanisms like poor blood flow or oxidative stress. Supplements targeting these alternative pathways may provide additional protection for the optic nerve. However, maintaining consistent use of prescribed medications is always the priority. Discuss supplement use with your ophthalmologist as part of your overall treatment plan.
Can ginkgo biloba help preserve my vision in glaucoma?
Some studies suggest ginkgo biloba may improve visual field and ocular blood flow in glaucoma patients, but results have been mixed. Ginkgo appears most promising as a complementary therapy alongside pressure-lowering treatments rather than a standalone intervention. Because ginkgo can interact with blood thinners and may increase bleeding risk during surgery, get medical clearance before using it.
Do I need glaucoma supplements if I don’t have symptoms?
Glaucoma is often called the “silent thief of sight” because it typically has no symptoms until significant damage occurs. If you’ve been diagnosed with glaucoma, you should follow your treatment plan regardless of whether you feel symptoms. Supplements might provide additional support, but they cannot replace prescription medications or monitoring by your ophthalmologist.
Can vitamin C help with glaucoma?
While vitamin C is a powerful antioxidant that may protect optic nerve cells, there’s limited evidence it significantly affects eye pressure. Some older research suggested high-dose vitamin C might modestly lower pressure, but these effects haven’t been consistently replicated. Vitamin C may be more valuable for its neuroprotective properties than any pressure-lowering effect.
Are there supplements I should avoid with glaucoma?
Some supplements may theoretically increase eye pressure, though evidence is limited. Be cautious with high-dose steroids, licorice root, and possibly large amounts of caffeine. Conversely, some medications for glaucoma can interact with supplements—for example, carbonic anhydrase inhibitors may interact with vitamin supplements. Always inform both your ophthalmologist and pharmacist about all supplements you take.
Can omega-3s help slow glaucoma progression?
Emerging research suggests omega-3 fatty acids may offer neuroprotective benefits in glaucoma. Some studies show omega-3s can help preserve retinal ganglion cell function and reduce inflammatory damage. While not proven to stop progression, omega-3s appear safe and may provide modest additional protection alongside standard treatments. They also offer cardiovascular benefits.
Should I take different supplements for different types of glaucoma?
The approach to supplementation is generally similar across glaucoma types, focusing on neuroprotection, antioxidants, and circulation support. However, normal-tension glaucoma, where pressure isn’t elevated, might particularly benefit from supplements targeting blood flow like ginkgo biloba. Discuss your specific type of glaucoma with your doctor to determine if certain supplements are more appropriate for your situation.
