Best Metagenics Vitamins
Metagenics stands as the #1 doctor-recommended professional supplement brand, offering clinically proven, precision-crafted formulas for whole-body wellness. Founded on functional medicine principles, Metagenics delivers pharmaceutical-grade supplements that healthcare practitioners trust for their patients. From comprehensive multivitamins to targeted formulas for specific health concerns, Metagenics combines cutting-edge research with high-quality ingredients to support your health goals at the cellular level.
Our Top Picks at a Glance
- Best Overall: Metagenics PhytoMulti — comprehensive multivitamin with 20+ phytonutrients
- Best Value: Metagenics Multigenics — foundational multi with proven formula
- Best Premium: Metagenics Vitamin D3 + K — synergistic formula for bone and heart health
Quick Comparison
| Product | Key Ingredients | Form | Servings | Best For |
|---|---|---|---|---|
| PhytoMulti Without Iron | 20+ Vitamins, Minerals, Phytonutrients | Tablets | 120 | Comprehensive nutrition |
| Multigenics | B12, Folic Acid, Calcium, Magnesium | Tablets | 180 | Daily foundation |
| PhytoMulti Capsules | Essential Vitamins & Phytonutrients | Capsules | 60 | Capsule preference |
| B-Complex | Active B6, B12, Folate | Tablets | 180 | Energy metabolism |
| Ultra Potent-C 1000 | 1000mg Buffered Vitamin C | Tablets | 90 | Immune support |
| Vitamin D3 5000 IU | 5000 IU Cholecalciferol | Softgels | 120 | Vitamin D supplementation |
| Vitamin D3 + K | D3 10,000 IU + MK-7 (K2) | Softgels | 60 | Bone & heart health |
1. Metagenics PhytoMulti Without Iron — Best Overall
- Provides 20+ essential vitamins, minerals, and plant‑based phytonutrients to support cellular health, energy metabolism, and immune defense*
- Includes antioxidants such as resveratrol, lutein, and zeaxanthin to protect against oxidative stress and support healthy aging*
- Non‑GMO, gluten‑free, and vegetarian tablets manufactured in a cGMP‑certified facility and third‑party tested for purity and potency*
- Certified B Corporation; trusted by healthcare practitioners for clinically tested, science‑backed daily nutrition*
- As the #1 Doctor Recommended Professional Supplement Brand, Metagenics delivers clinically proven, precision-crafted formulas to support your health at its core—because true wellness starts with integrity, balance, and expertise
The ultimate multivitamin featuring 20+ essential nutrients plus phytonutrients from a Mediterranean diet.
PhytoMulti delivers comprehensive daily nutrition with a proprietary blend of 13 concentrated plant extracts and phytonutrients found in healthy Mediterranean diets. This formula provides antioxidants like resveratrol, lutein, and zeaxanthin to protect against oxidative stress while supporting healthy aging. The iron-free formula is ideal for men and postmenopausal women who don’t need additional iron supplementation.
What We Like
- Comprehensive formula with 20+ vitamins, minerals, and phytonutrients
- Includes powerful antioxidants from Mediterranean plant sources
- Third-party tested for purity and potency
- Non-GMO, gluten-free, and vegetarian
What Could Be Better
- Requires taking 2 tablets twice daily
- Premium pricing reflects pharmaceutical-grade quality
Bottom Line: PhytoMulti provides the most comprehensive multivitamin formula from Metagenics, combining essential nutrients with research-backed phytonutrients for optimal cellular health.
2. Metagenics Multigenics — Best Value
- Comprehensive Multivitamin: Features essential vitamins and minerals including B12, folic acid, calcium, magnesium, and beta-carotene*
- Fast-Release Tablets: Designed for optimal disintegration and digestibility with rapid nutrient delivery*
- Bone & Heart Support: Provides a 2-to-1 ratio of calcium to magnesium along with nutrients that support cardiovascular and immune health*
- Trusted Quality: Non-GMO, gluten-free, vegetarian; manufactured in GMP Certified facilities with rigorous testing for purity and potency*
- As the #1 Doctor Recommended Professional Supplement Brand, Metagenics delivers clinically proven, precision-crafted formulas to support your health at its core because true wellness starts with integrity, balance, and expertise
A foundational multivitamin with proven efficacy for everyday wellness.
Multigenics provides comprehensive nutritional support with essential vitamins and minerals including B12, folic acid, calcium, and magnesium in a 2-to-1 ratio. The fast-release formula ensures optimal disintegration and digestibility for rapid nutrient delivery. This formula supports bone health, cardiovascular function, immune defense, and cellular wellness.
What We Like
- Balanced 2-to-1 calcium-to-magnesium ratio for bone support
- Fast-release tablets for enhanced absorption
- 180-tablet bottle provides excellent value
- Includes 10mg iron for those who need it
What Could Be Better
- Contains iron (not ideal for everyone)
- Basic formula lacks specialized phytonutrients
Bottom Line: Multigenics offers a trusted, cost-effective multivitamin that delivers comprehensive nutritional support for daily wellness maintenance.
3. Metagenics PhytoMulti Capsules — Best Capsule Formula
- Comprehensive Daily Support: Provides over 20 essential vitamins and minerals, including B6, B12, zinc, and selenium, to support overall wellness and energy metabolism*
- Concentrated Phytonutrients: Features a proprietary blend of 13 concentrated extracts and phytonutrients inspired by a Mediterranean-style diet to support cellular health and healthy aging*
- Immune, Brain & Eye Support: Nutrients including vitamins A, C, D, and E plus zinc and lutein help support immune function, cognitive health, and vision*
- Multivitamin for Men & Women: Formulated as a multivitamin for men and women, PhytoMulti supports overall wellness, healthy aging, and key body functions*
- As the #1 Doctor Recommended Professional Supplement Brand, Metagenics delivers clinically proven, precision-crafted formulas to support your health at its core‚ because true wellness starts with integrity, balance, and expertise
The same powerful PhytoMulti formula in easy-to-swallow capsules.
PhytoMulti Capsules deliver the comprehensive nutrition of the tablet version in a format preferred by those who have difficulty swallowing tablets. This formula provides essential vitamins A, C, D, E, K, plus B-complex vitamins, zinc, and a phytonutrient blend to support immune function, cognitive health, vision, and overall wellness.
What We Like
- Easier to swallow than tablets for many users
- Same research-backed phytonutrient blend as tablet version
- Supports multiple body systems simultaneously
- Doctor-recommended professional-grade formula
What Could Be Better
- 60-count bottle lasts only 30 days
- Capsules may be larger than some prefer
Bottom Line: PhytoMulti Capsules provide premium multivitamin nutrition in a capsule format that’s easier to take for those who dislike tablets.
4. Metagenics B-Complex — Best B Vitamin Formula
- Comprehensive B Vitamin Blend: Provides active forms of B6, B12, and folate to support daily energy metabolism and a healthy stress response*
- Supports Nervous System & Mood: B vitamins play a key role in maintaining nervous system function and supporting emotional well-being*
- Homocysteine & Heart Health: Folate, B6, and B12 work together to support healthy homocysteine metabolism, cardiovascular function, and brain health*
- Nutrient-Rich and Trusted Formula: Provides vitamin C, thiamin, riboflavin, myo-inositol, and PABA for comprehensive support; vegetarian and gluten-free, manufactured in GMP-certified facilities with third-party testing for purity and potency*
- As the #1 Doctor Recommended Professional Supplement Brand, Metagenics delivers clinically proven, precision-crafted formulas to support your health at its core‚ because true wellness starts with integrity, balance, and expertise
High-potency B vitamins for energy metabolism and stress response support.
Metagenics B-Complex features active forms of B6 and B12 vitamins along with folate to support energy metabolism, nervous system health, and homocysteine balance. This formula includes additional nutrients like vitamin C, thiamin, riboflavin, myo-inositol, and PABA for comprehensive B-vitamin support.
What We Like
- Contains active, bioavailable forms of key B vitamins
- Supports energy production and stress response
- 180 tablets provide 90-day supply
- Vegetarian and gluten-free formulation
What Could Be Better
- High B-vitamin doses may cause bright yellow urine (harmless)
- Best taken with food to prevent nausea
Bottom Line: Metagenics B-Complex delivers therapeutic doses of active B vitamins to support energy, stress response, and overall vitality.
5. Metagenics Ultra Potent-C 1000 — Best Vitamin C
- High Potency Immune Support: Delivers 1,000 mg of buffered vitamin C per tablet to support daily immune defense and collagen formation*
- Antioxidant Protection: Vitamin C helps support cellular health and overall wellness*
- Gentle on the Stomach: Buffered formulation designed to reduce stomach discomfort often associated with high-dose vitamin C*
- Clean & Trusted Formula: Non-GMO and gluten-free. Manufactured in GMP-certified facilities with third-party testing for purity and potency*
- As the #1 Doctor Recommended Professional Supplement Brand, Metagenics delivers clinically proven, precision-crafted formulas to support your health at its core‚ because true wellness starts with integrity, balance, and expertise
Buffered high-potency vitamin C that’s gentle on the stomach.
Ultra Potent-C provides 1000mg of vitamin C per tablet in a buffered formulation designed to reduce stomach discomfort often associated with high-dose vitamin C. This formula supports immune health, collagen formation, and provides powerful antioxidant protection while being gentle enough for daily use.
What We Like
- 1000mg vitamin C per tablet for immune support
- Buffered formula prevents stomach upset
- Supports collagen production for healthy skin and joints
- Third-party tested for quality and purity
What Could Be Better
- 90-count bottle requires monthly reordering
- May cause loose stools at high doses (common with all vitamin C)
Bottom Line: Ultra Potent-C 1000 delivers therapeutic vitamin C doses in a stomach-friendly formula that supports immune function and antioxidant defense.
6. Metagenics Vitamin D3 5000 IU — Best Vitamin D
No products found.
High-potency vitamin D3 in coconut oil for enhanced absorption.
Metagenics Vitamin D3 5000 IU provides cholecalciferol (the most bioavailable form of vitamin D) suspended in coconut oil to optimize absorption. This formula supports immune function, bone health, heart health, and calcium metabolism while addressing common vitamin D deficiency.
What We Like
- 5000 IU dose effectively addresses deficiency
- Coconut oil base enhances fat-soluble vitamin absorption
- 120 softgels provide 4-month supply
- Non-GMO and gluten-free
What Could Be Better
- High dose requires monitoring vitamin D levels
- Softgels may stick together in warm conditions
Bottom Line: Metagenics Vitamin D3 5000 IU provides therapeutic vitamin D supplementation in an optimally absorbed form for comprehensive health support.
7. Metagenics Vitamin D3 + K — Best Synergistic Formula
No products found.
Combines high-dose vitamin D3 with vitamin K2 for optimal bone and cardiovascular health.
This advanced formula pairs 10,000 IU of vitamin D3 with 180 mcg of MK-7 (vitamin K2) for synergistic benefits. Vitamin K2 directs calcium to bones and teeth while preventing arterial calcification, making this combination ideal for comprehensive bone and heart health support.
What We Like
- Synergistic D3 and K2 combination for enhanced benefits
- Supports both artery and bone health simultaneously
- MK-7 form of K2 has longest half-life
- 60 softgels provide 2-month supply
What Could Be Better
- Very high D3 dose requires medical supervision
- Not suitable for those on blood thinners without doctor approval
Bottom Line: Metagenics Vitamin D3 + K provides the most advanced vitamin D supplementation by including K2 for comprehensive bone and cardiovascular support.
How to Choose
Selecting the right Metagenics supplement begins with identifying your primary health goals. For comprehensive daily nutrition, the PhytoMulti formulas provide the most complete support with vitamins, minerals, and phytonutrients. If you’re addressing specific deficiencies or health concerns, targeted formulas like B-Complex, Vitamin D3, or Ultra Potent-C offer therapeutic doses of specific nutrients.
Consider your current supplement routine and any overlap with existing products. If you’re already taking a basic multivitamin, you might benefit more from specialized formulas targeting specific needs. However, if you’re starting fresh or looking to simplify your routine, PhytoMulti or Multigenics can serve as comprehensive foundations that reduce the need for multiple separate supplements.
Form preference matters for consistent use. Metagenics offers tablets, capsules, and softgels across different products. Tablets typically cost less and last longer, while capsules and softgels may be easier to swallow. Consider whether you prefer taking supplements once daily or can manage multiple doses throughout the day for better absorption.
Professional guidance enhances results with Metagenics products. These pharmaceutical-grade supplements are designed for use under practitioner supervision, as healthcare providers can recommend specific formulas based on lab work, symptoms, and health history. If you’re working with a functional medicine doctor, nutritionist, or naturopath, ask which Metagenics products they recommend for your situation.
Budget and value calculations should account for cost per serving rather than bottle price. While Metagenics products command premium prices, they deliver pharmaceutical-grade quality with third-party testing and clinically studied ingredients. A 180-count bottle lasting three months often provides better value than cheaper brands requiring twice-daily dosing with inferior ingredients.
Benefits
Metagenics supplements deliver pharmaceutical-grade quality backed by clinical research and practitioner trust. The brand’s commitment to purity testing, non-GMO ingredients, and GMP-certified manufacturing ensures you’re getting exactly what’s on the label—no fillers, no hidden ingredients, just pure, potent nutrition. This quality standard explains why Metagenics holds the #1 position among doctor-recommended supplement brands.
The phytonutrient advantage sets Metagenics apart from basic multivitamins. Products like PhytoMulti don’t just provide isolated vitamins and minerals—they include concentrated plant extracts with proven health benefits. These phytonutrients offer antioxidant protection, support healthy aging, and provide benefits that synthetic vitamins alone cannot deliver. This whole-food approach mirrors how humans evolved to obtain nutrition from plants.
Targeted formulations address specific health concerns more effectively than one-size-fits-all approaches. Whether you need immune support (Ultra Potent-C), energy enhancement (B-Complex), or bone health (Vitamin D3 + K), Metagenics offers specialized formulas designed around clinical research. This precision targeting often delivers faster, more noticeable results than general multivitamins.
Bioavailability and absorption optimization ensure your body can actually use the nutrients provided. Metagenics uses active vitamin forms (like methylfolate instead of folic acid), chelated minerals for better absorption, and strategic combinations that enhance nutrient uptake. For example, their Vitamin D3 in coconut oil significantly improves fat-soluble vitamin absorption compared to dry tablet forms.
Frequently Asked Questions
Are Metagenics supplements worth the higher price?
Yes, for those prioritizing quality and efficacy. Metagenics uses pharmaceutical-grade ingredients, conducts third-party testing, and bases formulas on clinical research. While more expensive than drugstore vitamins, they deliver superior absorption, potency, and results. Healthcare practitioners trust Metagenics precisely because the higher price reflects genuinely better quality, not just marketing.
Can I take Metagenics supplements without a doctor’s supervision?
While Metagenics products are available for direct purchase, they’re designed as professional-grade supplements often requiring practitioner guidance for optimal results. Basic products like multivitamins are generally safe for self-use following label directions, but specialized formulas may benefit from professional oversight to ensure appropriate dosing and avoid interactions with medications or health conditions.
How do Metagenics multivitamins compare to drugstore brands?
Metagenics multivitamins use higher-quality, more bioavailable nutrient forms (like methylfolate vs folic acid), include therapeutic doses rather than minimal amounts, and add beneficial phytonutrients not found in basic multivitamins. They undergo more rigorous testing and use cleaner manufacturing processes. The difference in quality and effectiveness justifies the price premium for those serious about nutritional support.
What makes PhytoMulti different from regular multivitamins?
PhytoMulti combines essential vitamins and minerals with a proprietary blend of 13 concentrated plant extracts and phytonutrients from a Mediterranean diet. These include powerful antioxidants like resveratrol, lutein, and zeaxanthin that protect cells from oxidative damage and support healthy aging—benefits you can’t get from synthetic vitamins alone.
Should I choose PhytoMulti with or without iron?
Adult men and postmenopausal women typically don’t need additional iron and should choose the iron-free version to avoid excess accumulation. Menstruating women, pregnant women, and anyone with confirmed iron deficiency should consider the version with iron or take a separate iron supplement. Your healthcare provider can test iron levels to guide this decision.
How long does it take to see results from Metagenics supplements?
Timeline varies by product and individual. Energy-focused formulas like B-Complex may show effects within days to weeks. Immune support products like Ultra Potent-C work relatively quickly during acute needs. Foundational multivitamins and bone health formulas require consistent use for 2-3 months before noticing significant changes. Lab work often reveals improvements before you feel them subjectively.
Can I take multiple Metagenics products together?
Many Metagenics products are designed to work together, but avoid duplicating nutrients unnecessarily. For example, don’t take both Multigenics and PhytoMulti simultaneously as both are complete multivitamins. However, you could combine a multivitamin with targeted formulas like B-Complex or Vitamin D3. Consult with a healthcare practitioner to design an optimal supplement stack.
Are Metagenics supplements third-party tested?
Yes, Metagenics products undergo rigorous third-party testing for purity and potency. They’re manufactured in GMP-certified facilities and tested to ensure they contain what’s on the label without contaminants. This quality control is a key reason healthcare practitioners trust the brand for their patients.
