Best Astragalus Supplements for Immunity (2026) – Top 10 Reviewed
Astragalus root has been a cornerstone of traditional Chinese medicine for over 2,000 years, prized for its ability to strengthen the body’s natural defenses and support overall vitality. Today, this adaptogenic herb remains one of the most popular immune-supporting supplements on the market.
The best astragalus supplements deliver standardized extracts with high polysaccharide content—the active compounds responsible for immune benefits. Here are our top 10 picks for 2026.
| Product | Key Ingredients | Servings | Form | Best For |
|---|---|---|---|---|
| Zazzee Extra Strength Astragalus 20:1 | 5000mg, 70% Polysaccharides | 180 | Capsules | Best Overall |
| NOW Astragalus Extract 500mg | 500mg, 70% Polysaccharides | 90 | Veg Capsules | Best Value |
| Double Wood Astragalus 500mg | 500mg 4:1 Extract | 180 | Capsules | Best for Heart Health |
| Nature’s Way Astragalus Root | 1410mg Whole Root | 180 | Vegan Capsules | Best Traditional Formula |
| Oregon’s Wild Harvest Organic Astragalus | 1125mg Organic Root | 180 | Capsules | Best Organic Option |
| Gaia Herbs Astragalus Supreme | Astragalus + Schisandra | 60 | Liquid Phyto-Caps | Best Adaptogenic Blend |
| NOW Foods Astragalus 500mg | 500mg Whole Root | 100 | Capsules | Best Budget Option |
| Vitamatic Astragalus 10:1 | 500mg 10:1 Extract | 200 | Veg Capsules | Best High Count |
| NusaPure Astragalus 20:1 | 6000mg Equivalent | 200 | Veg Capsules | Best with BioPerine |
| Horbaach Astragalus Tincture | Concentrated Liquid | 60 | Liquid Drops | Best Liquid Form |
1. Zazzee Extra Strength Astragalus Root 20:1 Extract – Best Overall
Why it stands out: This concentrated 20:1 extract delivers 5,000mg strength per capsule with a standardized 70% polysaccharide content—one of the highest on the market. The six-month supply makes it an exceptional value for serious immune support.
Zazzee’s formula uses a potent extraction method that concentrates the beneficial compounds found in astragalus root by a factor of 20. This means each capsule contains the equivalent potency of 20 capsules of regular astragalus powder. The 70% polysaccharide standardization ensures you’re getting a consistent, verified dose of the immune-active components with every capsule—not just hoping the right compounds are present.
Each bottle contains 180 vegan capsules, providing a full six months of daily supplementation at the recommended one-capsule-per-day dosage. The product is manufactured in the USA in a GMP-certified facility and undergoes third-party testing for purity, potency, and contaminants. The formula is completely free from common allergens including gluten, soy, dairy, eggs, fish, shellfish, and tree nuts, making it suitable for those with multiple food sensitivities.
What sets Zazzee apart from competitors is their transparency about standardization. Many astragalus products simply state they contain “extract” without specifying the concentration of active compounds. Zazzee clearly labels their 70% polysaccharide content, allowing informed comparison shopping.
Pros:
- Highest polysaccharide concentration available (70%)
- Exceptional value with 6-month supply
- Potent 20:1 concentrated extract
- Vegan and allergen-free
- Third-party tested for quality assurance
Cons:
- Higher strength may be too potent for beginners
- Large capsule size may be difficult for some to swallow
Best for: Anyone seeking maximum potency and long-term immune support at an unbeatable value.
2. NOW Astragalus Extract 500mg – Best Value
Why it stands out: NOW Foods delivers pharmaceutical-grade astragalus extract standardized to 70% polysaccharides at an incredibly affordable price point, backed by over five decades of supplement industry expertise and rigorous quality standards.
NOW has been producing quality supplements since 1968, and their astragalus extract reflects that experience and commitment to excellence. Each vegetarian capsule contains 500mg of standardized extract with guaranteed 70% polysaccharide content. The formula supports healthy immune cell function and has been studied for its role in liver and vascular health.
What makes NOW’s formula particularly effective is their attention to the science behind astragalus. Non-clinical studies have demonstrated that astragalus can support the healthy production and activity of specialized white blood cells, including T-cells and macrophages. This scientific approach to traditional herbalism is what separates NOW from many competitors.
NOW’s GMP-certified facilities hold an NPA A-rating, meaning every aspect of their manufacturing process has been examined and verified, including laboratory testing methods for stability, potency, and product formulation. The product is soy-free, non-GMO, and suitable for vegetarians and vegans. The company remains family-owned and operated, maintaining their commitment to quality over profit margins.
Pros:
- Affordable price from a trusted 55+ year brand
- Standardized to 70% polysaccharides
- NPA A-rated GMP-certified production
- Suitable for vegetarians and vegans
- Soy-free and Non-GMO
Cons:
- Requires 2 capsules per serving for optimal dosage
- 90 capsules provides only 45 servings
Best for: Budget-conscious buyers who want standardized extract quality from a highly reputable brand.
3. Double Wood Astragalus 500mg – Best for Heart Health
Why it stands out: Double Wood’s formula is specifically designed with cardiovascular support in mind, featuring a 4:1 extract rich in flavonoids and polysaccharides that support both immune and heart health simultaneously.
Double Wood Supplements focuses on research-backed formulations, and their astragalus extract is no exception. The 4:1 concentrated extract delivers the equivalent of 2,000mg of raw astragalus root per two-capsule serving. This moderate concentration ratio preserves a broader spectrum of beneficial compounds compared to ultra-concentrated extracts while still providing meaningful potency improvements over whole-root powders.
Research shows astragalus may help support T-cell activation and overall immune resilience. The herb is also rich in flavonoids—powerful antioxidant compounds that contribute to cardiovascular health. This dual benefit makes Double Wood’s formula particularly popular among those seeking immune support without neglecting heart health, especially as both concerns often increase with age.
Double Wood recommends taking 500mg (2 capsules) daily with a meal as the standard dosage for kidney, cardiovascular, or immune system health. The dosage can be increased up to 4 capsules if needed, though they advise not exceeding 6 capsules daily. Each bottle contains 300 capsules for a nearly five-month supply at the standard dosage, making it an excellent long-term value.
The product is manufactured in the USA from globally sourced ingredients, is Non-GMO, and is gluten-free. All Double Wood supplements undergo third-party testing to verify purity and potency.
Pros:
- Rich in flavonoids for cardiovascular support
- Third-party tested for purity and potency
- Five-month supply per bottle
- Manufactured in the USA
- Moderate concentration preserves compound diversity
Cons:
- Not standardized for specific polysaccharide percentage
- Requires 2 capsules per serving
Best for: Those seeking immune support with added cardiovascular and kidney health benefits.
4. Nature’s Way Astragalus Root – Best Traditional Formula
Why it stands out: Nature’s Way offers whole astragalus root in its natural form, providing a traditional approach that delivers the herb’s full spectrum of beneficial compounds exactly as nature intended.
For over 50 years, Nature’s Way has been a leader in herbal supplements, and they were one of the first major U.S. supplement companies to become TRU-ID certified, using DNA testing to authenticate plant species. Their astragalus root capsules contain 1,410mg per three-capsule serving of pure, non-extracted astragalus root. This whole-herb approach appeals to those who prefer their supplements closer to their natural state, providing the complete array of synergistic compounds found in the raw root.
The formula is Non-GMO Project Verified and uses plant-derived capsules made from hypromellose (vegetable cellulose), making it suitable for vegans and those avoiding animal-derived gelatin. The only other ingredient is cellulose—no fillers, stearates, or artificial additives. The company’s commitment to quality includes rigorous testing for identity, purity, and potency at multiple stages of production.
While whole-root products don’t deliver the concentrated punch of standardized extracts, many herbalists and traditional medicine practitioners prefer them for their balanced, gentle approach. The full spectrum of compounds may work synergistically in ways that isolated extracts don’t replicate. This makes Nature’s Way an excellent choice for those taking astragalus as a daily tonic.
Pros:
- Whole-herb formula with full spectrum of compounds
- Non-GMO Project Verified with TRU-ID certification
- Vegan-friendly plant-derived capsules
- Trusted brand with 50+ years experience
- Clean formula with minimal ingredients
Cons:
- Requires 3 capsules per serving (6 daily for full dose)
- Lower potency than concentrated extracts
- Larger serving size means bottles don’t last as long
Best for: Traditionalists who prefer whole-herb supplements over concentrated extracts and value gentle, balanced formulas.
5. Oregon’s Wild Harvest Organic Astragalus – Best Organic Option
Why it stands out: USDA Certified Organic and grown on the company’s own Oregon farm, this premium astragalus uses mature primary roots for maximum potency and represents the gold standard for clean, sustainable herbal supplements.
Oregon’s Wild Harvest takes organic seriously—they grow many of their herbs on their own certified organic farm in Redmond, Oregon, where they’ve been cultivating medicinal plants since 1994. Their astragalus capsules feature premium-grade root, classified as such due to the age and size of the roots used. Traditional Chinese medicine has long recognized that active components are concentrated in primary taproots, and that levels are highest in older, more mature plants—Oregon’s Wild Harvest honors this traditional wisdom.
The clean formula contains only organic astragalus root and organic pullulan capsules derived from naturally fermented tapioca starch—nothing else. No excipients, no stearates, no flow agents, no fillers. The product is certified organic by Oregon Tilth, one of the most respected organic certifiers in the country. It’s also verified Non-GMO by SGS, an independent third-party lab.
This traditional Chinese herb has been supporting the body’s natural defense systems for over 3,000 years. Oregon’s Wild Harvest processes their herbs in small batches for optimum potency, and their “open the bottle and inhale” philosophy reflects their confidence in the freshness and purity of their products. The 180-count bottle provides a two-month supply at the recommended three-capsules-daily dosage.
Pros:
- USDA Certified Organic by Oregon Tilth
- Premium-grade mature primary roots
- Made without excipients, stearates, or fillers
- Small-batch processing for freshness
- Company grows herbs on their own farm
- Verified Non-GMO
Cons:
- Premium price point
- Not standardized for polysaccharides
- Contains allergen warning for those sensitive to peanuts or chickpeas
Best for: Organic purists who want the cleanest, most natural astragalus supplement available from a company they can trust.
6. Gaia Herbs Astragalus Supreme – Best Adaptogenic Blend
Why it stands out: This synergistic formula combines astragalus with schisandra berry and ligustrum to create a comprehensive adaptogenic blend that supports both immune function and the body’s healthy stress response—a traditional Chinese medicine approach.
Gaia Herbs has been formulating herbal supplements for over 35 years from their Regenerative Organic Certified farm in North Carolina, and their Astragalus Supreme represents their expertise in traditional Chinese medicine formulations. Rather than offering isolated astragalus, they’ve created a balanced formula based on classical herbal pairings.
The liquid phyto-cap technology uses vegetable glycerin extraction to preserve the herb’s beneficial compounds and deliver them in a form that’s easier for the body to absorb than dried powders. Schisandra berry (wu wei zi) adds liver support and helps the body adapt to stress—it’s one of the few herbs classified as benefiting all five yin organs in Chinese medicine. Ligustrum fruit (nu zhen zi) contributes to overall vitality and is traditionally used to support healthy aging.
What sets Gaia apart is their Meet Your Herbs traceability program, which allows you to enter a code from your bottle and see exactly where your herbs were sourced, how they were grown, and their test results for purity and potency. This level of transparency is rare in the supplement industry. All products are screened for pesticides, microbes, and heavy metals.
The recommended dosage is 2 capsules twice daily between meals, meaning each 60-capsule bottle provides a 15-day supply—or 30 days at a reduced maintenance dose.
Pros:
- Synergistic adaptogenic blend based on traditional Chinese medicine
- Liquid phyto-cap technology for enhanced absorption
- Full traceability of ingredients via Meet Your Herbs
- Supports both immune function and stress response
- Grown on Regenerative Organic Certified farmland
Cons:
- Requires 4 capsules daily for full benefit
- Higher price per serving than single-herb products
- 60-capsule bottle only lasts 15 days at full dose
Best for: Those seeking comprehensive adaptogenic support beyond just immune function, especially during stressful periods.
7. NOW Foods Astragalus 500mg – Best Budget Option
Why it stands out: At under $10 for 100 capsules of pure astragalus root, this is the most affordable way to add this traditional Chinese herb to your daily wellness routine without compromising on quality.
NOW’s basic astragalus formula provides 500mg of whole astragalus root per capsule without the premium price of standardized extracts. While not as concentrated as their extract version, this formula still delivers the full range of astragalus compounds including flavonoids, free amino acids, trace minerals, and polyphenols—all the components that Chinese herbalists have valued for centuries.
The recommended dosage is 2 capsules, 2-3 times daily with meals, which means the 100-capsule bottle provides approximately 16-25 days of use depending on your dosing schedule. For those taking a maintenance dose of just 2 capsules daily, it extends to a 50-day supply. The formula is GMP-certified with NPA A-rating and Non-GMO verified, making it a reliable choice for those new to astragalus or on a tight budget.
This is an excellent starter option for those curious about astragalus who aren’t ready to commit to premium extracts, or for experienced users who want to maintain their astragalus intake affordably between cycles of higher-potency products.
Pros:
- Extremely affordable price point
- From trusted manufacturer with 55+ year history
- Non-GMO verified
- Good entry-level option for beginners
- GMP-certified production
Cons:
- Not standardized for polysaccharides
- Lower potency than extracts
- Requires multiple capsules per serving
Best for: First-time astragalus users and budget-conscious consumers who want quality without premium pricing.
8. Vitamatic Astragalus 10:1 Extract – Best High Count
Why it stands out: With 200 vegetarian capsules featuring a potent 10:1 extract, Vitamatic delivers excellent value for those who want a moderate-strength formula that provides over six months of daily immune support.
Vitamatic’s astragalus extract uses a 10:1 concentration ratio, meaning each 500mg capsule delivers the equivalent of 5,000mg of raw astragalus root. This mid-range potency sits in a sweet spot—more concentrated than basic whole-root supplements but not as intense as ultra-concentrated 20:1 extracts. For many users, this balanced approach is ideal for daily, long-term supplementation.
The 10:1 extraction preserves a broader spectrum of the plant’s beneficial compounds compared to more aggressive extraction methods, while still delivering meaningful concentration improvements over powdered root. The formula is Non-GMO, gluten-free, and uses vegetarian capsules suitable for those avoiding animal products.
With 200 capsules per bottle at a one-capsule daily serving, you get nearly seven months of supplementation—one of the longest supplies available in a single bottle. This makes Vitamatic an excellent choice for those who want to set up a long-term supplementation routine without frequent reordering.
Pros:
- 200 capsules per bottle for extended supply
- Moderate 10:1 extraction preserves compound diversity
- Vegetarian-friendly formula
- Over 6-month supply at standard dosing
- Competitive price per capsule
Cons:
- Not standardized for specific polysaccharide content
- Less potent than 20:1 extracts
Best for: Those seeking a moderate-potency extract with exceptional per-capsule value and long-term convenience.
9. NusaPure Astragalus 20:1 Extract – Best with BioPerine
Why it stands out: NusaPure enhances their potent 20:1 astragalus extract with BioPerine black pepper extract to boost absorption and bioavailability.
NusaPure’s formula stands out for its addition of BioPerine, a patented black pepper extract shown to enhance nutrient absorption by up to 30%. Each capsule delivers 300mg of 20:1 extract, equivalent to 6,000mg of raw astragalus root. The formula is designed for maximum potency and utilization. With 200 vegetarian capsules per bottle, you get excellent long-term value combined with enhanced absorption technology.
Pros:
- BioPerine for enhanced absorption
- Potent 20:1 extraction
- 200 capsule count
- Non-GMO formula
Cons:
- Some may prefer astragalus without additives
Best for: Those concerned about absorption and wanting maximum benefit from each dose.
10. Horbaach Astragalus Root Tincture – Best Liquid Form
Why it stands out: This alcohol-free liquid tincture offers rapid absorption and flexible dosing for those who prefer not to swallow capsules.
Horbaach’s super-concentrated liquid extract provides a convenient alternative to capsules. The alcohol-free formula uses vegetable glycerin as the extraction medium, making it gentler on the stomach and suitable for those avoiding alcohol. Liquid supplements typically absorb faster than capsules since they bypass the dissolution step in digestion. The 2 fl oz bottle provides 60 servings and can be taken directly or mixed into water, juice, or smoothies.
Pros:
- Fast-absorbing liquid form
- Alcohol-free extraction
- Flexible dosing options
- Easy to add to beverages
Cons:
- Shorter supply than capsule options
- May have herbal taste
Best for: Those who dislike swallowing pills or prefer faster-absorbing liquid supplements.
What is Astragalus and Who Should Take It?
Astragalus (Astragalus membranaceus), also known as Huang Qi in Chinese medicine, is a flowering plant native to northern China and Mongolia. The root has been used in traditional Chinese medicine for thousands of years as a “Qi tonic” believed to strengthen the body’s vital energy and defensive systems. In fact, it’s one of the most commonly prescribed herbs in traditional Chinese medicine, often appearing in formulas designed to boost overall vitality and resistance to illness.
Modern research has identified several bioactive compounds responsible for astragalus’s effects. Polysaccharides (particularly Astragalus Polysaccharide or APS) are the primary immune-active compounds, shown to stimulate the activity of macrophages, natural killer cells, and T-lymphocytes. Flavonoids provide antioxidant benefits and support cardiovascular health. Saponins (astragalosides) contribute to the herb’s adaptogenic properties. The root also contains amino acids, trace minerals, and other phytonutrients that work synergistically.
Astragalus may be particularly beneficial for those looking to support their immune system during seasonal challenges or times of increased stress, people experiencing chronic fatigue or low energy, individuals seeking cardiovascular or kidney health support, those recovering from illness who want to rebuild their resilience, anyone interested in adaptogens that help the body manage physical and emotional stress, and older adults looking to support healthy aging and immune function.
Unlike echinacea or elderberry, which are typically used for acute immune challenges, astragalus is traditionally considered a “constitutional” or tonic herb—meaning it’s meant to be taken regularly over extended periods to build and maintain health rather than as a quick fix when you’re already sick. Many practitioners actually recommend avoiding high-dose astragalus during acute illness and reserving it for preventive and restorative use.
How to Choose the Right Astragalus Supplement
Key Ingredients to Look For
The most important factor in astragalus supplements is polysaccharide content. Look for products standardized to at least 50-70% polysaccharides, as these are the primary immune-active compounds responsible for stimulating immune cell activity. The extraction ratio also matters significantly—a 20:1 extract is more concentrated than a 4:1 extract, meaning you need less of it to achieve the same effect. A 20:1 extract means 20 pounds of raw root were used to create 1 pound of extract, concentrating the beneficial compounds.
Some premium formulas also standardize for astragalosides, another group of beneficial saponin compounds associated with the herb’s adaptogenic and cardioprotective effects. While less common, astragaloside standardization (typically around 0.5-1%) indicates a higher quality product. Additionally, some products include complementary herbs like schisandra or ligustrum that traditionally pair with astragalus in Chinese medicine formulas.
Forms Compared
Capsules and tablets are the most popular form, offering convenience and precise dosing. Standardized extracts in capsule form typically deliver the most consistent potency and are ideal for those who want guaranteed active compound levels. Liquid tinctures absorb faster and work well for those who dislike pills, though they may have an earthy, slightly sweet taste and typically require refrigeration after opening.
Powders offer flexibility in dosing and can be added to smoothies, teas, or other beverages, but require measuring and may have a strong herbal flavor. Whole-root capsules provide a traditional, less processed option that delivers the full spectrum of compounds present in the raw root, but at lower concentrations than extracts. Liquid phyto-caps (like Gaia Herbs uses) combine the benefits of liquid extraction with capsule convenience.
What to Avoid
Steer clear of products that don’t specify their extraction ratio or polysaccharide content, as potency can vary dramatically between brands—sometimes by a factor of 10 or more. Avoid formulas loaded with unnecessary fillers, artificial colors, preservatives, or flow agents like magnesium stearate if you prefer clean supplements.
Be wary of extremely cheap products that may use lower-quality root material harvested prematurely, secondary roots instead of primary taproots, or inadequate extraction methods. Traditional Chinese medicine specifically values mature, large primary roots for their higher concentration of active compounds. Always choose supplements from reputable manufacturers that provide third-party testing results and can verify the source of their ingredients.
Side Effects and Precautions
Astragalus is generally considered safe for most adults when taken at recommended doses, and it has a long history of traditional use supporting its safety profile. Some people may experience mild digestive effects including bloating, gas, or loose stools, which can usually be minimized by taking the supplement with food or starting with a lower dose and gradually increasing. Allergic reactions are rare but possible, particularly in those with sensitivities to legumes—astragalus is a member of the Fabaceae (bean and pea) family, so those allergic to peanuts, chickpeas, or other legumes should exercise caution.
Those who should consult a doctor before using astragalus include people taking immunosuppressant medications (such as those prescribed after organ transplants), as astragalus may counteract these drugs. Those with autoimmune conditions like lupus, rheumatoid arthritis, or multiple sclerosis should be cautious since astragalus stimulates immune activity, which could potentially exacerbate autoimmune responses. Pregnant or nursing women should consult their healthcare provider before use, as safety during pregnancy has not been established. Anyone taking blood thinners or diabetes medications should also seek medical guidance, as astragalus may affect blood sugar levels and bleeding time.
Astragalus may interact with lithium by affecting how the body eliminates this medication. It may also interact with cyclophosphamide and other immunosuppressive drugs. If you’re scheduled for surgery, discontinue astragalus at least two weeks beforehand due to its potential effects on immune function and bleeding.
FAQs
What is the best dosage for astragalus supplements?
Most studies and traditional use suggest 250-500mg of standardized extract daily, or 2-6 grams of whole root. Many supplements recommend 500-1000mg of extract per day, typically split into two doses. Start with a lower dose and increase gradually to assess tolerance.
When is the best time to take astragalus?
Astragalus can be taken any time of day, though many prefer morning or early afternoon since it may provide an energy boost. Taking it with food can help minimize any potential digestive discomfort. For best results, maintain consistent daily timing.
How long does it take to see results from astragalus?
Astragalus works as a tonic herb, meaning benefits accumulate over time rather than appearing immediately. Most users report noticeable improvements in energy and resilience after 4-8 weeks of consistent use. Some immune benefits may appear sooner during seasonal challenges.
Can I take astragalus with other supplements?
Astragalus pairs well with many other immune-supporting supplements including vitamin C, zinc, elderberry, and medicinal mushrooms like reishi. It’s also commonly combined with other adaptogens like ashwagandha and rhodiola. However, consult your healthcare provider before combining multiple supplements.
Is astragalus safe for daily long-term use?
Unlike some immune herbs meant for short-term acute use, astragalus is traditionally considered safe and beneficial for long-term daily supplementation. In Chinese medicine, it’s classified as a “superior” herb suitable for extended use. Most people can take it continuously, though taking occasional breaks (such as one week off per month) is reasonable.
Who should not take astragalus?
Avoid astragalus if you have an autoimmune condition like lupus, rheumatoid arthritis, or multiple sclerosis unless approved by your doctor. Those on immunosuppressant drugs after organ transplants should not use it. Pregnant and breastfeeding women should consult healthcare providers before use.
Final Verdict
For most people seeking powerful, long-term immune support, Zazzee Extra Strength Astragalus offers the best combination of potency, value, and quality. Its 20:1 extract with 70% standardized polysaccharides delivers clinical-grade strength at an unbeatable six-month supply price. You simply won’t find a more potent, well-documented astragalus supplement at this value point.
If you’re on a budget, NOW Astragalus Extract provides the same 70% polysaccharide standardization at a fraction of the cost, backed by one of the most trusted names in supplements. It’s an excellent choice for those who want verified potency without premium pricing.
For those who prefer organic supplements and value knowing exactly where their herbs come from, Oregon’s Wild Harvest Organic Astragalus delivers premium USDA-certified quality from a company that grows herbs on their own Oregon farm. The clean, minimal-ingredient formula appeals to purists who want nothing but the herb itself.
And if you want comprehensive adaptogenic support beyond just immunity—especially during stressful periods—Gaia Herbs Astragalus Supreme blends traditional Chinese herbs for stress and vitality support with full ingredient traceability.
Whichever product you choose, remember that astragalus works best as a long-term tonic. Give it at least 4-8 weeks of consistent daily use before evaluating results, and consider making it a regular part of your wellness routine rather than a short-term solution.
