Best Cat Kidney Support Supplements (2026) – Top 10 Reviewed
Kidney disease is one of the most common health challenges senior cats face, affecting nearly one-third of older felines. While no supplement can reverse kidney damage, the right formula can help support remaining kidney function, manage symptoms, and improve your cat’s quality of life. From phosphate binders to herbal blends, we’ve reviewed the best kidney support supplements to help you give your cat the extra care they need.
Our Top Picks at a Glance
- Best Overall: AminAvast Kidney Support for Cats – Patented amino acid formula backed by clinical studies
- Best Value: VetriScience Renal Essentials for Cats – Comprehensive chewable at an affordable price
- Best Premium: Pet Wellbeing Kidney Support Gold – Vet-formulated herbal liquid supplement
Quick Comparison
| Product | Key Ingredients | Form | Servings | Best For |
|---|---|---|---|---|
| AminAvast Kidney Support 300mg | Amino Acids, Peptides (AB070597) | Sprinkle Capsules | 60 | Overall kidney function support |
| VetriScience Renal Essentials for Cats | B Vitamins, Fish Oil, Herbs, Mushrooms | Chewable Tablets | 120 | Comprehensive daily kidney care |
| Pet Wellbeing Kidney Support Gold | Rehmannia, Dong Quai, Astragalus | Liquid | 60+ | Herbal kidney and fluid balance |
| Vetoquinol Azodyl Kidney Health | S. thermophilus, L. acidophilus, B. longum | Capsules | 60 | Probiotic waste elimination |
| Kidney Restore for Cats & Dogs | Probiotics, Sodium Bicarbonate, Niacinamide | Powder | 60+ | Toxin support and pH balance |
| Rx Vitamins Phos-Bind | Chitosan Phosphate Binder | Powder | 200g | Phosphorus level management |
| Standard Process Feline Renal Support | Whole-Food Based Ingredients | Tablets | 90 | Whole-food kidney nutrition |
| HomeoPet Feline Kidney Rescue | Homeopathic Blend | Liquid Drops | 90+ | Natural homeopathic kidney support |
1. AminAvast Kidney Support for Cats 300mg – Best Overall
- Daily Support For Renal Health; our proprietary blend of amino acids and a peptide can help support healthy renal function in cats and dogs. No side effects have been reported in cats that have been using AminAvast for both short-term and long-term use.
- Easy To Administer For Life; our sprinkle capsules can be easily broken and mixed in food to make daily consumption a breeze for your pet. No need for refrigeration and comes with a three-year shelf life.
- Veterinarian Recommended; clinical studies have shown that dogs’ and cats’ health can improve just weeks after starting the supplement. It may be used in conjunction with other treatments and medications depending on your veterinarian's recommendations.
- Patented proprietary formula: AminAvast, patent # US 9669010 B2, is manufactured in a USA-based, GMP certified facility, and we are a proud member of the National Animal Supplement Council (NASC). We are committed to developing products of the highest quality to improve and extend the lives of our companion animals.
- Supports normal kidney function, hydration, coat quality, energy, appetite, and urinary tract health; ideal for cat urinary support or as a daily cat and small dogs kidney supplement for pets weighing 20 lbs or less. See Benefits Within Weeks: Owners have reported improvements in their pet's hair coat, appetite, weight gain, behavior and overall quality of life.
AminAvast stands apart as the only kidney supplement with a patented formula of amino acids and peptides specifically researched for feline renal health.
The patented ingredient AB070597 is created through a proprietary process and has been shown in clinical studies to support normal kidney function. Cat owners consistently report improvements in coat quality, appetite, weight, and overall vitality within weeks of starting AminAvast. The sprinkle capsules can be easily opened and mixed into food.
With over a decade of veterinary recommendation behind it, AminAvast is manufactured in a GMP-certified USA facility and is a proud member of the National Animal Supplement Council (NASC). Each bottle contains 60 capsules — enough for a full 12 months of daily dosing for most cats.
What We Like
- Patented, clinically studied formula specifically for kidney support
- No reported side effects even with long-term use
- 60 capsules provide up to 12 months of daily dosing
What Could Be Better
- Higher upfront cost than basic kidney supplements
- Capsules need to be opened and sprinkled — some cats detect the powder
Bottom Line: AminAvast is the gold standard in feline kidney supplementation, offering the only patented amino acid formula backed by clinical studies and over a decade of veterinary trust.
2. VetriScience Renal Essentials for Cats – Best Value
No products found.
VetriScience packs everything your cat’s kidneys need into an affordable chewable tablet — from B vitamins to fish oils and adaptogenic herbs.
Renal Essentials supports kidney function by addressing homocysteine balance, fluid retention, stress management, and liver functions. The formula includes B vitamins for energy and red blood cell support, fish oils for anti-inflammatory benefits, and herbal ingredients like astragalus root and nettle seed for kidney-specific support.
Available in both chicken and fish flavors, these chewable tablets are reasonably well-accepted by cats. At 120 tablets per bottle, you get excellent value for a comprehensive kidney support formula.
What We Like
- Comprehensive formula covering B vitamins, omega-3s, and kidney-specific herbs
- 120-count bottle at an affordable price point
- Available in chicken and fish flavors
What Could Be Better
- Tablets may be too large for some cats — may need to dissolve in water
- Some picky eaters resist the chewable format
Bottom Line: VetriScience Renal Essentials delivers the most comprehensive kidney support at the best price, making it the ideal daily supplement for cats with early to moderate kidney concerns.
3. Pet Wellbeing Kidney Support Gold for Cats – Best Premium
- 🐾 SUPPORTS DAILY ROUTINES – Helps maintain normal metabolism, weight, thirst, and urination patterns to support comfort and ease throughout the day. Encourages steady energy and hydration, helping cats feel their best during play, rest, and everyday activities.
- 🌱 SUSTAINABLY SOURCED INGREDIENTS – Features carefully cultivated herbs chosen for purity, consistency, and gentle effectiveness. Sustainably harvested to ensure high-quality support that’s as good for the planet as it is for your cat.
- 💧 CAT-FRIENDLY LIQUID FORMULA – Alcohol-free liquid designed for easy absorption and precise administration. Enhanced with a natural bacon flavor that most cats enjoy, even those with selective tastes, making daily wellness support simple.
- 🏆 VETERINARIAN-FORMULATED QUALITY – Proudly made in the USA in FDA-registered facilities, NASC certified for quality, and third-party tested for safety and potency. Expertly developed by veterinarians and herbalists for trustworthy care.
- 🌿 HERBAL KIDNEY WELLNESS – Gentle yet effective veterinarian-formulated blend of herbs traditionally used to help maintain normal kidney function. Supports the body’s natural balance while contributing to overall vitality and well-being in cats of all ages.
Formulated by holistic veterinarians and clinical herbalists, Kidney Support Gold uses time-tested herbs to support renal function from multiple angles.
This liquid supplement features rehmannia, dong quai, and astragalus — herbs traditionally used to support kidney function, fluid balance, and energy levels. The alcohol-free formula is made in FDA-registered facilities and carries NASC certification for quality assurance.
The liquid format allows for optimal absorption and precise dosing based on your cat’s weight. Pet Wellbeing has over 3,000 reviews from cat owners, many reporting significant improvements in their cat’s energy, appetite, and overall quality of life.
What We Like
- Holistic vet-formulated with traditional kidney-supporting herbs
- Liquid format for precise dosing and superior absorption
- Made in FDA-registered facilities with NASC certification
What Could Be Better
- Premium price for a 2 oz bottle
- Some cats may resist the herbal flavor
Bottom Line: Pet Wellbeing’s herbal approach to kidney support is the premium choice for cat owners who want vet-formulated, plant-based renal care for their feline companion.
4. Vetoquinol Azodyl Kidney Health Supplement – Best Probiotic Approach
No products found.
Azodyl takes a unique probiotic approach to kidney health by using beneficial bacteria to help eliminate waste products that build up when kidneys aren’t working properly.
This veterinarian-recommended supplement contains three beneficial bacterial strains — Streptococcus thermophilus, Lactobacillus acidophilus, and Bifidobacterium longum — that help metabolize uremic toxins in the gut. By diverting waste elimination to the intestines, Azodyl reduces the burden on compromised kidneys.
The supplement is well-tolerated by both cats and dogs and is one of the most commonly prescribed kidney supplements by veterinarians. Recent studies have shown that probiotics can dramatically improve blood markers for kidney disease in cats.
What We Like
- Unique probiotic mechanism for eliminating uremic toxins through the gut
- Well-tolerated with minimal side effects
- One of the most veterinarian-recommended kidney supplements
What Could Be Better
- Requires refrigeration to maintain probiotic viability
- Capsules can be difficult to administer to some cats
Bottom Line: Azodyl’s innovative probiotic approach to managing kidney waste makes it a valuable addition to any renal care regimen, especially for cats with elevated BUN or creatinine levels.
5. Kidney Restore for Cats & Dogs – Best Multi-Action Formula
- This all natural and 100% safe kidney health supplement, developed specifically for the dogs and cats you love to support normal kidney function, urinary health and owners reported healthier happier pets w/ healthier kidneys! This gentle holistic supplement has scientifically formulated ingredients to help support normal kidney function, detoxification, renal health, urinary tract health and enhance immunity.
- Powerful blend of toxin-consuming probiotics, boosted by prebiotics, sodium bicarbonate and niacinamide to further strengthen the kidney benefits. Balances vital nutrients, such as phosphorus, that can build up and harm kidneys. Rest easy knowing their BUN, eGFR and creatinine are supported for normal kidney health.
- Rejuvenate, maintain and support long-term renal health & function for aging canine and feline pets by supporting normal blood pressure, strengthening kidneys against stressors & revitalize renal cells. Safe to use with medications; instructions for eBook access on pkg, 'How to best use Kidney Restore for Cats & Dogs,' & product support by health coaches. This is a REAL natural way to have healthier kidneys without adverse reactions.
- The probiotic microorganisms help your kidneys by supporting natural elimination of poisonous toxins in the gut, the sodium bicarb neutralizes kidney acids & toxins, and balances minerals. Niacinamide safely lowers harmful phosphorus levels, Vitamin C provides powerful antioxidants for kidney cells. Easy to feed, unflavored formula; simply sprinkle & mix into meals.
- Recommended by veterinarians for supporting normal kidney function in senior pets without harmful drugs. Also promoting urination control, proper hydration levels; enhancing appetite for healthy weight gain; notice a healthier and shinier coat of hair, less hair loss, reduce excess fluid and so much more. This is the most complete kidney supplement available for your cats and dogs kidneys.
Created by a naturopath who personally understands kidney issues, Kidney Restore offers the most comprehensive ingredient profile on the market.
This powder supplement combines toxin-consuming probiotics, sodium bicarbonate (to neutralize kidney acids), niacinamide (to lower harmful phosphorus levels), and Vitamin C (for antioxidant protection). The formula is designed to support BUN, eGFR, and creatinine levels while promoting proper hydration and appetite.
The unflavored powder mixes easily into food, and the comprehensive approach addresses kidney health from multiple angles — detoxification, pH balance, mineral management, and immune support.
What We Like
- Most comprehensive ingredient list targeting multiple kidney health markers
- Includes probiotics, pH buffers, and phosphorus-lowering niacinamide
- Created by someone with personal kidney health experience
What Could Be Better
- Designed for both dogs and cats — requires dosage adjustment
- Some cats may notice the powder in their food
Bottom Line: Kidney Restore offers the most thorough approach to kidney supplementation, addressing toxin elimination, pH balance, and mineral management in one formula.
6. Rx Vitamins Phos-Bind – Best Phosphate Binder
No products found.
High phosphorus levels are one of the biggest dangers in feline kidney disease, and Phos-Bind is specifically designed to keep them under control.
This chitosan-based phosphate binder works by binding to phosphorus in your cat’s food during digestion, preventing it from being absorbed into the bloodstream. Since compromised kidneys can’t effectively filter phosphorus, using a binder like Phos-Bind helps keep levels safe without requiring restrictive dietary changes.
The powder format mixes easily into food and doesn’t interfere with other treatments or supplements. It’s frequently recommended by veterinarians as a key component of managing kidney disease in cats.
What We Like
- Specifically targets phosphorus management — critical for kidney disease
- Doesn’t interfere with other medications or supplements
- Large 200g container lasts a long time
What Could Be Better
- Only addresses phosphorus — doesn’t provide other kidney support
- Should be used under veterinary guidance for proper dosing
Bottom Line: Phos-Bind is essential for cats with kidney disease and elevated phosphorus levels, serving as the cornerstone of any comprehensive renal supplement regimen.
7. Standard Process Feline Renal Support – Best Whole-Food Formula
No products found.
Standard Process takes a unique whole-food approach to kidney support, using nutrient-dense ingredients that your cat’s body can easily recognize and utilize.
This tablet supplement contains whole-food based ingredients specifically selected to support kidney and urinary health in cats. Standard Process is known for their farm-to-supplement approach, growing many of their own ingredients on their organic farm in Wisconsin.
The 90-tablet bottle provides a solid supply for daily use, and the whole-food ingredients are often better tolerated than synthetic alternatives. Many holistic veterinarians specifically recommend Standard Process products for their quality and bioavailability.
What We Like
- Whole-food based ingredients for superior bioavailability
- Trusted by holistic veterinarians for decades
- Farm-to-supplement quality with organic ingredient sourcing
What Could Be Better
- Tablets can be challenging to administer to some cats
- Premium pricing reflects the whole-food ingredient quality
Bottom Line: Standard Process delivers kidney support the way nature intended — through whole-food nutrition that your cat’s body can easily absorb and use.
8. HomeoPet Feline Kidney Rescue – Best Natural Remedy
No products found.
For cat owners who prefer a gentle, natural approach, HomeoPet’s Feline Kidney Rescue provides homeopathic support with no known side effects.
This liquid formula uses safe, natural homeopathic ingredients to support kidney function in cats and kittens of all ages. The drops can be administered directly into the mouth, mixed with water, or added to food — giving you maximum flexibility for picky cats.
Created by veterinarian Thomas Farrington, HomeoPet products are recommended by vets worldwide. The small bottle provides over 90 doses at the typical feline dosage, making it surprisingly economical for a specialty supplement.
What We Like
- Gentle homeopathic formula with no known side effects
- Flexible administration — mouth, water, or food
- Safe for cats and kittens of all ages
What Could Be Better
- Homeopathic approach may not suit all cats or conditions
- Results tend to be gradual rather than immediate
Bottom Line: HomeoPet Feline Kidney Rescue is the gentlest option for kidney support, ideal for cat owners who prefer a natural, side-effect-free approach to renal care.
How to Choose the Best Cat Kidney Support Supplement
Choosing the right kidney supplement starts with understanding your cat’s specific stage of kidney disease and their primary symptoms. Cats in early stages may benefit from general antioxidant and herbal support, while those with advanced disease often need targeted supplements like phosphate binders and probiotic toxin managers.
Consider the administration format carefully. Cats with kidney disease often have reduced appetites, making it challenging to give supplements that alter the taste or texture of food. Liquid supplements and unflavored powders tend to be the easiest to administer to compromised cats. Chewable tablets work well for cats that still have a healthy appetite.
Look for supplements that address the specific complications of kidney disease. High phosphorus levels, uremic toxin buildup, dehydration, and anemia are common issues. A good kidney supplement should address at least one or two of these concerns, and many cat owners find that using two complementary supplements provides better results than a single product.
Quality certifications matter enormously for kidney supplements. Look for NASC seals, GMP manufacturing, veterinary formulation, and clinical studies. Kidney disease is a serious condition, and you want absolute confidence in the quality of what you’re giving your cat.
Always work with your veterinarian when selecting kidney supplements. Your vet can monitor blood values to determine which supplements are most needed and whether they’re making a measurable difference. Regular bloodwork is essential for cats with kidney disease, regardless of supplementation.
Benefits of Cat Kidney Support Supplements
The most significant benefit of kidney supplements is their ability to slow the progression of kidney disease and manage its symptoms. By reducing the workload on compromised kidneys — through phosphorus binding, toxin elimination, and antioxidant protection — supplements help preserve remaining kidney function for longer.
Many kidney supplements improve quality of life in measurable ways. Cat owners frequently report better appetite, increased energy, improved coat quality, and more normal hydration patterns after starting supplementation. These everyday improvements can add months or even years of comfortable life for cats with kidney disease.
Kidney supplements can also help manage secondary complications of renal disease. B vitamins support red blood cell production to combat renal anemia, omega-3 fatty acids reduce inflammation and protect remaining kidney tissue, and probiotics help manage toxin levels that the kidneys can no longer effectively filter.
Frequently Asked Questions
Can kidney supplements cure kidney disease in cats?
No, kidney disease in cats is not curable. However, supplements can help support remaining kidney function, manage symptoms, and slow disease progression. Used alongside proper veterinary care and a kidney-appropriate diet, supplements can significantly improve your cat’s quality and length of life.
When should I start giving my cat kidney supplements?
Many veterinarians recommend starting kidney supplements when routine bloodwork shows subtle changes in kidney values, even before obvious symptoms develop. For senior cats (10-12 years and older), preventative supplementation with antioxidants and omega-3s can help protect kidney health proactively.
Can I give kidney supplements alongside prescribed kidney medication?
Most kidney supplements are safe to use alongside prescribed medications, but always confirm with your veterinarian. Some supplements may interact with certain medications or may duplicate effects, so your vet can help you create the optimal supplementation plan.
How do I know if kidney supplements are working?
The best way to measure effectiveness is through regular veterinary bloodwork monitoring BUN, creatinine, and phosphorus levels. You may also notice improvements in your cat’s energy, appetite, coat quality, and overall demeanor at home.
What role does diet play alongside kidney supplements?
Diet is fundamental to kidney disease management. Kidney-appropriate diets are typically lower in phosphorus and protein while being higher in moisture content. Supplements work best when paired with a proper renal diet as recommended by your veterinarian.
Are phosphate binders necessary for all cats with kidney disease?
Not always. Phosphate binders are most important for cats with elevated phosphorus levels, which typically occurs in more advanced stages of kidney disease. Your veterinarian can determine if your cat’s phosphorus levels warrant a binder based on regular blood tests.
How important is hydration for cats with kidney disease?
Hydration is critical. Cats with kidney disease often become dehydrated because their kidneys can’t concentrate urine effectively. Wet food, water fountains, and hydration supplements can all help. Some veterinarians also recommend subcutaneous fluid therapy for cats with advanced kidney disease.
Can young cats benefit from kidney supplements?
While kidney disease is most common in senior cats, younger cats can develop kidney issues from toxin exposure, infections, congenital conditions, or urinary blockages. If your young cat has been diagnosed with kidney problems, supplements can provide valuable support alongside veterinary treatment.
