Best Dog Calming Treats for Anxiety (2026) – Top 10 Reviewed

Anxiety in dogs is more common than many pet parents realize. Whether it’s thunderstorms, fireworks, separation, or car rides, stress can affect your dog’s quality of life and behavior. Calming treats offer a convenient, tasty way to help soothe anxious pups without prescription medications.

The best dog calming treats combine proven ingredients like melatonin, L-theanine, chamomile, and hemp at effective doses in a palatable chew your dog will actually eat. Here are our top 10 picks for 2026.

ProductKey IngredientsCountFormBest For
Melatonin Sleep Aid Treats 6mgMelatonin 6mg, Chamomile120Soft ChewsBest Overall
Advanced Calming Chews with 7 MushroomsAshwagandha, Omega-3, Mushroom Blend90Soft ChewsBest for Brain Support
Hemp Calming Chews with Duck FlavorHemp Oil, Chamomile, Valerian180Soft ChewsBest Value
Vet Recommended Calming ChewsMelatonin, Hemp, L-Theanine120Soft ChewsBest Vet Recommended
GABA & Melatonin Fast-Acting ChewsGABA, Melatonin, Ashwagandha180Soft ChewsBest Fast-Acting
Hemp Calming Chews 120ctHemp, Melatonin, Chamomile120Soft ChewsBest for Separation Anxiety
Deley Naturals Calming ChewsHemp, Valerian, Passionflower90Soft ChewsBest Natural Formula
Hemp Chews with Valerian & L-TryptophanValerian, L-Tryptophan, Hemp120Soft ChewsBest for Storms & Fireworks
Advanced 7 Mushroom Chews – ChickenMushroom Blend, Ashwagandha, DHA90Soft ChewsBest for Picky Eaters
BARK&SPARK Hemp + Melatonin TreatsHemp Oil, Melatonin, Chamomile120Soft ChewsBest Budget Option

1. Melatonin Sleep Aid Treats 6mg – Best Overall

Why it stands out: This extra-strength formula delivers 6mg of melatonin per treat—significantly higher than most competitors—making it ideal for medium to large breeds or dogs with severe nighttime anxiety.

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The combination of melatonin with chamomile creates a synergistic calming effect that helps dogs settle down for sleep. These chews work particularly well for dogs who pace at night, have trouble settling, or experience age-related sleep disruption. The formula is Made in USA and comes in a 120-count jar that lasts most dogs 2-4 months depending on size.

Pros:

  • Extra-strength 6mg melatonin per chew
  • Effective for nighttime anxiety and sleep issues
  • Made in USA with quality ingredients
  • Good value at 120 chews per container

Cons:

  • May be too strong for small dogs under 25 lbs

Best for: Medium and large breed dogs with nighttime anxiety or sleep difficulties.


2. Advanced Calming Chews with 7 Mushrooms – Best for Brain Support

Why it stands out: This innovative formula combines adaptogenic mushrooms with ashwagandha and omega-3 fatty acids to support both short-term calming and long-term brain health—a dual-action approach unique in the calming treat market.

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The seven-mushroom blend includes lion’s mane, reishi, and cordyceps, which research suggests may support cognitive function and stress resilience. Added omega-3 DHA and EPA support brain health while ashwagandha helps regulate cortisol. The salmon flavor is highly palatable, and these chews work for all breeds and sizes with weight-based dosing.

Pros:

  • Unique mushroom-based adaptogen formula
  • Supports both calming and cognitive health
  • Contains omega-3s for additional brain benefits
  • Suitable for all breeds and sizes

Cons:

  • Higher price point than basic calming treats
  • 90-count jar may not last as long for larger dogs

Best for: Pet parents looking for comprehensive anxiety and cognitive support in one treat.


3. Hemp Calming Chews with Duck Flavor – Best Value

Why it stands out: At 180 chews per bag with effective doses of hemp oil, chamomile, and valerian root, this product delivers exceptional value without compromising on quality ingredients.

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The duck flavor is a refreshing change from the typical chicken or beef options, making these a hit with dogs who’ve become bored with standard treats. The formula targets multiple anxiety triggers including thunderstorms, fireworks, separation, and car rides. Hemp oil provides a calming effect without any psychoactive compounds, while valerian and chamomile enhance relaxation.

Pros:

  • 180-count bag offers excellent value
  • Unique duck flavor appeals to picky eaters
  • Multi-purpose formula for various anxiety triggers
  • Hemp-based for gentle, natural calming

Cons:

  • Some dogs may need 30-60 minutes for full effect

Best for: Budget-conscious pet parents who need a large supply for ongoing anxiety management.


4. Vet Recommended Calming Chews – Best Vet Recommended

Why it stands out: Developed with veterinary input, this Made in USA formula combines melatonin, hemp, and L-theanine in clinically-informed ratios for reliable stress and behavior support.

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L-theanine, an amino acid found in green tea, promotes relaxation without drowsiness—making these chews suitable for daytime use when you still want your dog alert but calm. The extra-strength formula addresses situational stressors like travel, vet visits, and fireworks. The vet-developed backing gives pet parents confidence in the formulation’s safety and efficacy.

Pros:

  • Veterinarian-developed formula
  • Contains L-theanine for non-drowsy calming
  • Made in USA with quality assurance
  • Works for situational and chronic anxiety

Cons:

  • Pricier than some budget options

Best for: Pet parents who want a vet-backed formula they can trust for regular use.


5. GABA & Melatonin Fast-Acting Chews – Best Fast-Acting

Why it stands out: The GABA-forward formula provides noticeably faster onset than most calming treats—many pet parents report seeing effects within 20-30 minutes, making these ideal for unexpected stressors.

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GABA (gamma-aminobutyric acid) is a neurotransmitter that naturally calms the nervous system. Combined with melatonin for relaxation and ashwagandha for stress resilience, this formula offers both quick relief and long-lasting support. The 180-count bag means you’ll have plenty on hand for storms, fireworks seasons, or travel. Works for all breeds with weight-based dosing guidelines.

Pros:

  • Fast-acting GABA formula works in 20-30 minutes
  • Long-lasting calming with ashwagandha
  • Generous 180-chew count
  • Effective for multiple anxiety triggers

Cons:

  • GABA can cause mild drowsiness in some dogs

Best for: Dogs who need quick relief from sudden anxiety triggers like unexpected storms or visitors.


6. Hemp Calming Chews 120ct – Best for Separation Anxiety

Why it stands out: Specifically formulated with separation anxiety in mind, this blend addresses the prolonged stress dogs experience when left alone through a sustained-release approach with hemp and melatonin.

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Separation anxiety requires a different approach than situational stress—dogs need calming support that lasts for hours, not just during a storm. This formula combines hemp oil with melatonin and chamomile in ratios designed for extended relief. The Made in USA quality and 120-count supply make this a reliable daily option for dogs who struggle when their humans leave.

Pros:

  • Formulated specifically for separation anxiety
  • Sustained calming effect lasts several hours
  • Made in USA with quality hemp
  • 120-count supply for daily use

Cons:

  • Best given 30-45 minutes before departure

Best for: Dogs who exhibit destructive behavior, barking, or pacing when left alone.


7. Deley Naturals Calming Chews – Best Natural Formula

Why it stands out: This clean-label formula uses passionflower, valerian root, and hemp without artificial additives—ideal for pet parents who prioritize all-natural ingredients for their dogs.

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Deley Naturals has built a reputation for transparency and quality sourcing. Their calming chews feature passionflower, which has been used for centuries as a natural relaxant, alongside valerian and hemp. These chews work well for general restlessness, vet visits, travel anxiety, and storm phobias. The formula is free from artificial colors, flavors, and preservatives.

Pros:

  • All-natural, clean-label formula
  • Contains passionflower for gentle calming
  • No artificial additives or preservatives
  • Works for multiple anxiety triggers

Cons:

  • 90-count jar is smaller than some competitors

Best for: Pet parents who prefer natural, additive-free supplements for their dogs.


8. Hemp Chews with Valerian & L-Tryptophan – Best for Storms & Fireworks

Why it stands out: The combination of valerian root and L-tryptophan specifically targets noise-related anxiety, making these a go-to choice for dogs who panic during thunderstorms and fireworks.

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L-tryptophan is a precursor to serotonin, the “feel-good” neurotransmitter that promotes calm and well-being. Paired with valerian’s sedative properties and hemp’s calming effects, this formula addresses the intense fear response many dogs have to loud noises. The chicken flavor ensures high palatability, and the 120-count supply will get you through storm season or Fourth of July weekend.

Pros:

  • L-tryptophan supports serotonin production
  • Valerian provides natural sedative effects
  • Effective for noise phobias specifically
  • Pleasant chicken flavor

Cons:

  • Works best when given 45-60 minutes before storms

Best for: Dogs with severe noise phobias from thunder, fireworks, or construction sounds.


9. Advanced 7 Mushroom Chews – Chicken Flavor – Best for Picky Eaters

Why it stands out: Same proven mushroom-adaptogen formula as the salmon version, but in a chicken flavor that appeals to dogs who turn their nose up at fish-based treats.

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Getting a picky dog to eat supplements can be a challenge. This chicken-flavored version of the Advanced Calming formula makes compliance easy with a taste dogs actually enjoy. The seven-mushroom blend with ashwagandha and omega-3s provides the same brain and composure support. Works for all breeds and sizes with clear dosing instructions based on weight.

Pros:

  • Chicken flavor for picky eaters
  • Same advanced adaptogen formula
  • High palatability ensures compliance
  • Suitable for all dog sizes

Cons:

  • 90-count supply may require frequent reordering

Best for: Dogs who refuse fish-flavored treats but still need comprehensive calming support.


10. BARK&SPARK Hemp + Melatonin Treats – Best Budget Option

Why it stands out: This affordable formula delivers effective doses of hemp oil and melatonin at a price point that makes daily calming support accessible for any budget.

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Not every pet parent can afford premium calming supplements, but that shouldn’t mean their dog has to suffer from anxiety. BARK&SPARK delivers a solid hemp and melatonin formula with added chamomile at an accessible price. The 120-count supply offers good value, and the formula addresses common anxiety triggers including storms, fireworks, travel, and separation.

Pros:

  • Budget-friendly price point
  • Contains proven calming ingredients
  • 120 chews per container
  • Multi-purpose anxiety relief

Cons:

  • Simpler formula than premium options

Best for: Pet parents on a budget who need effective, everyday calming support.


How to Choose the Right Calming Treat for Your Dog

Key Ingredients to Look For

The most effective calming treats contain one or more of these proven ingredients: melatonin (regulates sleep-wake cycles and promotes relaxation), L-theanine (supports calm alertness), GABA (inhibitory neurotransmitter that reduces nervous system activity), valerian root (natural sedative herb), chamomile (gentle relaxation), and hemp oil (promotes overall calm without psychoactive effects). Ashwagandha is gaining popularity as an adaptogen that helps dogs cope with stress over time.

Size & Breed Considerations

Most calming treats provide weight-based dosing guidelines. Small dogs (under 25 lbs) typically need 1 chew, medium dogs (25-75 lbs) need 2 chews, and large dogs (over 75 lbs) may need 3 or more. Some breeds are more prone to anxiety—herding breeds, rescue dogs, and certain toy breeds often need stronger formulas or higher doses. Always start with the lower end of the recommended dose and adjust based on your dog’s response.

Form Factor: Soft Chews vs. Tablets vs. Liquids

Soft chews dominate the calming treat market because dogs find them palatable and they’re easy to administer. Tablets may be harder for picky dogs to accept but sometimes contain higher doses. Liquid formulas offer flexible dosing and can be added to food, though some dogs dislike the taste. For most dogs, soft chews offer the best balance of effectiveness and ease of use.

What to Avoid

Steer clear of calming treats that rely solely on low-quality hemp without listing actual hemp content, products with artificial colors and preservatives, or formulas that don’t disclose ingredient amounts. Be cautious of extremely cheap options that may contain fillers rather than active ingredients. Also avoid products marketed with unrealistic claims like “works instantly” or “cures anxiety permanently.”


Signs Your Dog May Need Calming Treats

  • Excessive barking or whining when left alone or during storms
  • Destructive behavior like chewing furniture, doors, or their own paws
  • Pacing, trembling, or hiding during stressful events
  • Restlessness at night or inability to settle down
  • Escape attempts during fireworks or thunderstorms
  • Excessive drooling or panting unrelated to heat or exercise
  • Refusal to eat in stressful situations like boarding or travel

If your dog shows severe symptoms like self-injury or complete shutdown during anxiety episodes, consult your veterinarian—they may need prescription intervention alongside or instead of calming treats.


Side Effects and Safety

Most dogs tolerate calming treats well, but some may experience mild drowsiness, especially with melatonin-heavy formulas. This is generally the desired effect but can be problematic if you need your dog alert. Start with half the recommended dose to assess your dog’s sensitivity, then adjust as needed.

Calming treats can interact with certain medications, particularly sedatives, antihistamines, and some heart medications. Always consult your vet before starting calming treats if your dog takes any prescription medications or has liver, kidney, or heart conditions. Pregnant or nursing dogs should avoid calming supplements unless specifically approved by a veterinarian.


FAQs

How many calming treats should I give my dog?

Follow the weight-based dosing on the package—typically 1 chew for dogs under 25 lbs, 2 for 25-75 lbs, and 3+ for dogs over 75 lbs. Start with the minimum dose and increase only if needed.

How long before a stressful event should I give calming treats?

Most calming treats work best when given 30-60 minutes before the anticipated stressor. For predictable events like fireworks or travel, timing is straightforward. For unexpected storms, give treats at the first sign of weather changes.

Can I give my puppy calming treats?

Most calming treats are safe for puppies over 12 weeks old, but always check the specific product label. Some formulas recommend waiting until 6 months. Puppies may need lower doses than adult dosing charts suggest.

Are there any side effects from dog calming treats?

The most common side effect is mild drowsiness, which is usually the intended effect. Some dogs may experience digestive upset when first starting. Rare reactions include increased anxiety—discontinue use if this occurs.

Can I use calming treats with other medications?

Calming treats can interact with sedatives, anti-anxiety medications, and some other drugs. Always consult your veterinarian before combining calming treats with any prescription medications.

How long can I give my dog calming treats?

Most calming treats are safe for long-term daily use, though it’s wise to give occasional breaks. For situational anxiety (storms, travel), use only as needed. For chronic anxiety, consider rotating between different formulas every few months.


Final Verdict

For most dogs with anxiety, we recommend Melatonin Sleep Aid Treats 6mg as the best overall option—the extra-strength formula provides reliable relief for medium to large dogs dealing with nighttime anxiety, separation stress, or noise phobias.

If you’re on a budget, Hemp Calming Chews with Duck Flavor delivers excellent value with 180 chews at an affordable price. For dogs who need quick relief, the GABA & Melatonin Fast-Acting Chews work faster than most alternatives.

Pet parents seeking a vet-backed formula should consider the Vet Recommended Calming Chews, while those preferring all-natural ingredients will appreciate Deley Naturals Calming Chews with its clean-label approach.

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