Best Dog Flea & Tick Treatments (2026) – Top 10 Reviewed
Fleas and ticks aren’t just annoying—they can transmit diseases and make your dog miserable. Whether you prefer natural prevention or need something with more punch, the right flea and tick treatment keeps your pup protected year-round.
The best flea and tick products for dogs combine effective ingredients with safety and ease of use. Natural chewable options have become increasingly popular for pet parents who want to avoid harsh chemicals. Here are our top 10 picks for 2026.
| Product | Key Ingredients | Count | Form | Best For |
|---|---|---|---|---|
| YOTANGO Flea & Tick Support Chewables | Natural Flea Support Blend | 500 | Crunchy & Creamy | Best Overall |
| 100% Natural Flea & Tick Prevention | Natural Ingredients | 120 | Soft Chews | Best Natural Option |
| Flea & Tick + Itch Relief Chewables | Flea Support + Allergy Relief | 200 | Soft Chews | Best for Itchy Dogs |
| 4-IN-1 Flea & Tick Prevention | Multi-System Support | 500 | Crunchy Chews | Best Multi-Benefit |
| Flea & Tick Support Drops | Omega-3, Natural Blend | Varies | Liquid Drops | Best for Picky Eaters |
| 5-in-1 Flea & Tick Treatment | Hip, Joint, Skin, Immunity, Digestive | Varies | Chewables | Best All-in-One |
| Flea & Tick Prevention 170ct | Natural Prevention Blend | 170 | Soft Chews | Best Value |
| Flea & Tick Support with Probiotics | Probiotics, Multivitamins | Varies | Supplement | Best with Digestive Support |
| 500ct Crunchy & Creamy Flea Chews | Natural Flea Support | 500 | Crunchy & Creamy | Best Large Supply |
| Chewable Flea & Tick Prevention | Skin & Coat Support | 120 | Soft Chews | Best for All Breeds |
1. YOTANGO Dog Flea and Tick Support Chewables – Best Overall
Why it stands out: With 500 crunchy and creamy chews in a beef flavor dogs love, this natural flea and tick support supplement offers excellent value and skin/coat benefits.
YOTANGO’s formula combines natural flea and tick support with skin and coat benefits in a unique crunchy and creamy texture dogs find irresistible. The beef flavor makes daily dosing easy, and the massive 500-count container means you won’t run out anytime soon. This works well as a daily supplement to help make your dog less appealing to pests while supporting overall health.
Pros:
- 500 chews per container—outstanding value
- Crunchy and creamy texture dogs love
- Supports skin and coat health
- Beef flavor is highly palatable
Cons:
- Results take consistent daily use over time
Best for: Pet parents wanting a long-term natural approach to flea and tick prevention.
2. 100% Natural Flea & Tick Prevention – Best Natural Option
Why it stands out: Made in the USA with natural ingredients, these bacon-flavored soft chews offer a chemical-free approach to flea and tick prevention.
For pet parents who prefer to avoid synthetic chemicals, this 100% natural formula provides an alternative to traditional treatments. The soft chews come in an irresistible bacon flavor that most dogs readily accept. At 120 chews per container, you get a four-month supply for daily prevention. This works by supporting your dog’s natural defenses rather than using pesticides.
Pros:
- 100% natural ingredients
- Made in the USA
- Bacon flavor dogs love
- Soft chew format is easy to give
Cons:
- May not be sufficient for heavy infestations
Best for: Health-conscious pet parents who want to avoid chemical treatments.
3. Flea & Tick + Itch Relief Chewables – Best for Itchy Dogs
Why it stands out: This dual-action formula addresses both flea prevention and the itching that often comes with pest problems or allergies.
If your dog scratches constantly—whether from fleas, allergies, or skin sensitivity—this combination product tackles both issues. The flea and tick support ingredients work alongside allergy relief compounds to reduce itching and promote skin repair. The chicken flavor appeals to most dogs, and 200 soft chews provide extended coverage.
Pros:
- Addresses fleas and itching simultaneously
- 200 soft chews per container
- Chicken flavor is palatable
- Supports skin health and repair
Cons:
- Two-in-one formulas may be less potent than dedicated products
Best for: Dogs who suffer from both pest problems and allergies or skin sensitivity.
4. 4-IN-1 Flea and Tick Prevention – Best Multi-Benefit
Why it stands out: This comprehensive formula supports flea prevention while also addressing skin, coat, gut, and immune health in one daily chew.
Why give multiple supplements when one can do it all? This 4-in-1 formula provides daily flea support alongside skin and coat care, digestive health, and immune support. The chicken flavor makes daily dosing easy, and the 500-count crunchy chews container offers serious value. This is ideal for pet parents who want to simplify their dog’s supplement routine.
Pros:
- Four health benefits in one product
- 500 crunchy chews—great value
- Chicken flavor dogs enjoy
- Simplifies daily supplementation
Cons:
- Jack-of-all-trades may not excel at any single benefit
Best for: Pet parents who want comprehensive daily support in one convenient product.
5. Flea and Tick Support Drops – Best for Picky Eaters
Why it stands out: Liquid drops with Omega-3 fatty acids offer an alternative for dogs who refuse chewable supplements.
Some dogs simply won’t eat chewable supplements no matter how tasty they seem. These chicken-flavored liquid drops can be added directly to food, making administration much easier. The Omega-3 fatty acids support healthy skin, which naturally helps make dogs less attractive to pests. This works well for puppies and small breeds who may struggle with larger chews.
Pros:
- Liquid format works for picky eaters
- Contains beneficial Omega-3 fatty acids
- Easy to add to food
- Suitable for puppies and all breeds
Cons:
- May need to mix with wet food for best results
Best for: Dogs who refuse chewable supplements or those who prefer liquid administration.
6. 5-in-1 Dog Flea and Tick Treatment – Best All-in-One
Why it stands out: Five-way support covers flea prevention plus hip and joint, skin and coat, immunity, and digestive health—replacing multiple supplements.
This comprehensive formula is designed for pet parents who want to address multiple health concerns with a single daily chew. Beyond flea and tick support, it provides joint care for active or aging dogs, skin and coat nourishment, immune system support, and digestive health benefits. It’s particularly valuable for senior dogs who might otherwise need several different supplements.
Pros:
- Five health benefits in one chew
- Great for senior dogs with multiple needs
- Supports overall wellness
- Reduces supplement fatigue
Cons:
- May not provide therapeutic doses for severe issues
Best for: Senior dogs or those with multiple health concerns who need comprehensive daily support.
7. Flea and Tick Prevention 170ct – Best Value
Why it stands out: At 170 treats per container with natural ingredients, this bacon-flavored option delivers solid prevention at an attractive price point.
Not everyone needs a 500-count mega container. This 170-count option hits the sweet spot between value and practicality for most households. The natural formula is made in the USA, and the bacon flavor ensures most dogs take their daily dose willingly. Soft chews work for dogs of all ages and sizes.
Pros:
- 170 chews at an attractive price
- Made in USA with natural ingredients
- Bacon flavor is highly palatable
- Good size for single-dog households
Cons:
- Smaller count than some competitors
Best for: Single-dog households looking for value without buying in bulk.
8. Flea and Tick Support with Probiotics – Best with Digestive Support
Why it stands out: This unique formula combines flea and tick support with probiotics and multivitamins for whole-body wellness.
The connection between gut health and overall wellness is well-established, and this product leverages that relationship. By combining flea support with probiotics and essential vitamins, it promotes healthy skin from the inside out while supporting digestion and immune function. The chicken flavor works for both dogs and cats, making it practical for multi-pet households.
Pros:
- Combines flea support with digestive health
- Includes probiotics and multivitamins
- Works for dogs and cats
- Supports skin health internally
Cons:
- Probiotic doses may be lower than dedicated products
Best for: Dogs who need both pest prevention and digestive support.
9. 500ct Crunchy & Creamy Flea Chews – Best Large Supply
Why it stands out: The 500-count container with tasty crunchy and creamy texture ensures you won’t run out of flea prevention anytime soon.
If you have multiple dogs or simply hate running out of supplies, this 500-count container has you covered. The crunchy and creamy texture makes these treats exciting for dogs—many see them as rewards rather than supplements. The natural formula supports flea prevention through daily use, and the chicken flavor appeals to most pups.
Pros:
- 500 chews—excellent for multi-dog homes
- Crunchy and creamy texture dogs love
- Natural formula
- Great per-chew value
Cons:
- Large container may expire before use for single dogs
Best for: Multi-dog households or pet parents who prefer buying in bulk.
10. Chewable Flea and Tick Prevention – Best for All Breeds
Why it stands out: Specifically formulated for all sizes from small dogs and puppies to large breeds, with added skin and coat support.
Made in the USA, this 120-count soft chew option works across the full spectrum of dog sizes and breeds. The formula includes skin and coat supporting ingredients that promote a healthy, pest-resistant coat. Whether you have a Chihuahua puppy or a Great Dane, dosing instructions make it easy to give the right amount.
Pros:
- Suitable for all breeds and sizes
- Made in USA
- 120 soft chews per container
- Includes skin and coat support
Cons:
- Mid-range count may not suit all budgets
Best for: Households with dogs of different sizes who need a versatile option.
How to Choose the Right Flea & Tick Treatment for Your Dog
Understanding Prevention vs Treatment
Natural chewable supplements work best as prevention—helping make your dog less appealing to pests before infestations occur. For existing infestations, you may need to combine these with other treatments like topical solutions or flea baths. Think of chewable supplements as part of a comprehensive pest management strategy.
Size and Breed Considerations
Most chewable flea products are dosed by your dog’s weight. Small breeds may only need one chew daily, while large breeds might need two or more. Some products offer size-specific formulas, while others provide universal dosing guidelines. Always check the label and adjust portions appropriately for your dog’s weight.
Form Factor: Chews vs Drops vs Topicals
Chewables are convenient and most dogs take them readily. Liquid drops work well for picky eaters when added to food. Traditional topical treatments and collars offer different mechanisms of action. Some pet parents combine natural chewables with occasional topical treatments for maximum protection during peak pest season.
What to Avoid
Be cautious of products that make claims that seem too good to be true. Natural supplements support your dog’s defenses but typically won’t eliminate severe infestations on their own. Avoid products with undisclosed ingredients or those manufactured in facilities without quality certifications.
Signs Your Dog May Have Fleas or Ticks
- Excessive scratching or biting at skin: The most obvious sign of flea activity
- Red, irritated skin or hot spots: Flea bites cause allergic reactions in many dogs
- Flea dirt (tiny black specks) in fur: Flea feces look like pepper flakes in your dog’s coat
- Visible fleas or ticks on skin: Part the fur to inspect, especially around ears and belly
- Hair loss, particularly around the tail base: A classic sign of flea allergy dermatitis
- Restlessness or unusual agitation: Dogs with fleas often can’t settle down
- Pale gums in severe cases: Heavy infestations can cause anemia, especially in puppies
If you notice a tick attached to your dog, remove it promptly with tweezers or a tick removal tool, pulling straight out without twisting.
Side Effects and Safety
Natural flea and tick chewables are generally well-tolerated by most dogs. Some may experience mild digestive upset when first starting a new supplement—this typically resolves within a few days. Introduce new products gradually and monitor your dog for any unusual reactions.
If your dog has known food allergies, check ingredient lists carefully. Many products contain common proteins like chicken or beef. Dogs with sensitive stomachs may do better with products that include digestive support ingredients. Pregnant or nursing dogs should have veterinary approval before starting any new supplements.
FAQs
How long do natural flea and tick supplements take to work?
Natural supplements work differently than chemical treatments—they support your dog’s system over time rather than providing immediate killing action. Most products recommend 4-6 weeks of consistent daily use before expecting to see full benefits. They work best as prevention rather than treatment for existing infestations.
Can I use natural chewables with topical flea treatments?
Yes, natural chewable supplements can typically be used alongside topical treatments or flea collars. In fact, many pet parents use this combination approach during peak flea and tick season. Always check with your vet if you’re unsure about combining products.
Are these safe for puppies?
Most natural flea chewables are safe for puppies over 8-12 weeks old, but check individual product labels for specific age recommendations. Puppies should receive weight-appropriate doses, which are typically smaller than adult portions.
Do I need to give these year-round?
In most climates, year-round prevention is recommended. Fleas can survive indoors during winter months, and ticks may remain active in temperatures above 40°F. Consistent daily use provides the best protection.
What if my dog already has fleas?
Natural supplements alone may not eliminate an existing infestation. You’ll likely need to combine them with baths, thorough home cleaning, and potentially other treatments. Once the infestation is cleared, continue with preventive supplements to avoid recurrence.
Can these replace prescription flea medications?
Natural supplements offer a different approach than prescription medications and may not provide the same level of protection. Discuss your options with your vet, especially if your dog has had severe flea problems or lives in a high-risk area for tick-borne diseases.
Final Verdict
For comprehensive natural flea and tick prevention, YOTANGO Flea & Tick Support Chewables offers the best combination of value, palatability, and multi-system support with its 500-count container.
Pet parents who prioritize all-natural ingredients should consider 100% Natural Flea & Tick Prevention for its clean formula and Made in USA quality. If your dog struggles with itching alongside pest issues, the Flea & Tick + Itch Relief Chewables address both concerns effectively.
For senior dogs or those with multiple health needs, the 5-in-1 Flea & Tick Treatment simplifies supplementation by combining five benefits in one daily chew.
