Best Dog Probiotic & Digestive Supplements (2026) – Top 10 Reviewed
Digestive supplements help dogs maintain healthy gut function, firm stools, and balanced gut flora. Whether your dog deals with occasional upset stomach, chronic loose stools, or digestive sensitivity, probiotics and digestive enzymes can make a significant difference.
The best dog digestive supplements combine multiple probiotic strains with prebiotics and digestive enzymes for complete gut support. Look for CFU counts (colony-forming units) and targeted formulas for your dog’s specific needs. Here are our top 10 picks for 2026.
Quick Comparison Table
| Product | Key Ingredients | Count | Form | Best For |
|---|---|---|---|---|
| STRELLALAB Probiotics + Enzymes | Probiotics, Digestive Enzymes | 180 | Chews | Best Overall |
| VetriScience Mega Probiotic Capsules | 7.5 Billion CFU Probiotics, Prebiotics | 180 | Capsules | Best High-Potency |
| Perfect Poop Digestion Supplement | Fiber, Prebiotics, Probiotics, Enzymes | 4.2 oz | Powder | Best Fiber Formula |
| VetriScience Gut Health Chews (Duck) | 1 Billion CFU, Prebiotics | 120 | Chews | Best Daily Maintenance |
| Vet Promise Super Poop Probiotics | 6 Probiotics, Digestive Enzymes, Fiber | 120 | Chews | Best for Firm Stools |
| Green Lawn Chews with Probiotics | Cranberry, Probiotics, ACV, Enzymes | 120 | Chews | Best Multi-Purpose |
| Poop Fixer Pumpkin Powder | Pumpkin, Carrot, Fiber | 13.4 oz | Powder | Best Natural Fiber |
| Probiotics for Dogs 170 Chews | Probiotics, Prebiotics, Enzymes | 170 | Chews | Best Value |
| Milk Thistle Liquid for Dogs | Milk Thistle Extract | 2 oz | Liquid | Best Liver Support |
| Anal Gland Support Chews | Fiber, Prebiotics, Digestive Enzymes | 120 | Chews | Best for Anal Gland Issues |
1. STRELLALAB Probiotics + Enzymes – Best Overall
Why it stands out: This comprehensive formula combines probiotics with digestive enzymes to tackle gut issues from multiple angles. The 180-count container provides excellent value, and pet parents consistently report improvements in gas, diarrhea, and overall digestive comfort.
STRELLALAB delivers both probiotics for gut flora balance and digestive enzymes for improved nutrient breakdown. This dual approach helps dogs who struggle with gas, loose stools, or upset stomach. The chicken-flavored chews are highly palatable, and at 180 chews, you’re getting months of daily support. The formula targets anti-gas benefits, diarrhea relief, and immune support through gut health optimization.
Pros:
- Probiotics plus digestive enzymes in one formula
- 180-count high-value container
- Addresses gas, diarrhea, and upset stomach
- Chicken flavor dogs love
Cons:
- CFU count not prominently featured
Best for: Dogs with general digestive issues including gas, loose stools, and stomach upset who need comprehensive gut support.
2. VetriScience Mega Probiotic Capsules – Best High-Potency
Why it stands out: With 7.5 billion CFU per capsule, this is one of the highest-potency probiotic formulas available. VetriScience’s veterinary-trusted brand and easy-open capsule format make it ideal for dogs needing maximum probiotic support.
VetriScience’s Extra Strength formula delivers mega-dose probiotics combined with prebiotics for optimal gut colonization. The 180-count container provides extended value, and the easy-open capsules can be given whole or sprinkled on food. This formula is designed for dogs and cats with persistent digestive issues who haven’t responded to lower-potency products. The veterinary-strength formulation targets diarrhea and immune support.
Pros:
- 7.5 billion CFU per capsule—highest potency
- Veterinary-trusted brand
- Easy-open capsules for flexible dosing
- 180-count container
Cons:
- Capsule format may be harder for some dogs than chews
Best for: Dogs with chronic digestive issues, post-antibiotic recovery, or those needing maximum probiotic support.
3. Perfect Poop Digestion Supplement – Best Fiber Formula
Why it stands out: This award-winning formula takes a four-pronged approach: fiber for bulk, prebiotics for gut bacteria food, probiotics for flora balance, and enzymes for digestion. The result is optimized stool quality and overall digestive health.
Perfect Poop has earned its cult following among dog owners. The cheddar cheese-flavored powder combines fiber to create properly-formed stools, prebiotics to feed beneficial bacteria, probiotics to populate the gut, and digestive enzymes to break down food efficiently. Many pet parents notice firmer, easier-to-pick-up poops within days. The 4.2 oz container mixes easily into food and works for dogs of all sizes.
Pros:
- Four-in-one formula (fiber, prebiotics, probiotics, enzymes)
- Noticeably improves stool quality
- Cheddar cheese flavor dogs love
- Addresses root causes of digestive issues
Cons:
- Powder format requires mixing into food
Best for: Dogs with inconsistent stools, those who produce difficult-to-manage waste, or any dog needing comprehensive digestive optimization.
4. VetriScience Gut Health Chews (Duck) – Best Daily Maintenance
Why it stands out: For dogs who need everyday digestive support rather than therapeutic intervention, this 1 billion CFU formula provides gentle, consistent gut health maintenance in a tasty duck-flavored chew.
Not every dog needs mega-dose probiotics. VetriScience’s everyday formula delivers 1 billion CFU per chew—enough for daily gut maintenance without overwhelming the system. The prebiotics feed beneficial bacteria already present, supporting natural gut balance. The duck flavor is gentle on sensitive stomachs while remaining appealing. At 120 chews, this is ideal for long-term daily use once digestive issues are under control.
Pros:
- Appropriate potency for daily maintenance
- Duck flavor easy on sensitive stomachs
- Trusted veterinary brand
- 120-count for extended use
Cons:
- May not be strong enough for severe digestive issues
Best for: Dogs with resolved digestive issues who need ongoing maintenance, or those with mildly sensitive stomachs.
5. Vet Promise Super Poop Probiotics – Best for Firm Stools
Why it stands out: Specifically designed to create perfect poops, this formula combines 6 probiotic strains with digestive enzymes and fiber to address loose stools, soft stool, and inconsistent bowel movements.
Vet Promise focuses on what many pet parents care about most: firm, well-formed stools that are easy to pick up. The formula includes 6 targeted probiotic strains, digestive enzymes for complete food breakdown, and fiber for proper stool formation. It works both as a stool softener for constipated dogs and a firming agent for those with loose stools. The 120 chews provide reliable daily support.
Pros:
- Specifically targets stool quality
- 6 probiotic strains for comprehensive coverage
- Works for both loose and hard stools
- Digestive enzymes included
Cons:
- Focuses on stool rather than broader digestive benefits
Best for: Dogs with chronic loose stools, inconsistent poop quality, or diarrhea-prone digestive systems.
6. Green Lawn Chews with Probiotics – Best Multi-Purpose
Why it stands out: This clever formula addresses digestive health while also tackling lawn burn from dog urine. The probiotics and digestive enzymes support gut function while cranberry and ACV help neutralize urine pH.
Green Lawn Chews solve two problems at once. The probiotics and digestive enzymes support healthy digestion and gut flora balance. Meanwhile, cranberry, apple cider vinegar, and other ingredients help neutralize the nitrogen in dog urine that causes lawn burn. The 120 chews also support bladder and urinary tract health. For pet parents tired of yellow lawn spots who also want digestive support, this formula delivers.
Pros:
- Addresses digestive health AND lawn burn
- Probiotics with ACV and cranberry
- Supports urinary tract health
- 120-count container
Cons:
- May be unnecessary if lawn health isn’t a concern
Best for: Pet parents dealing with both digestive issues and lawn damage from dog urine.
7. Poop Fixer Pumpkin Powder – Best Natural Fiber
Why it stands out: Sometimes simple is best. This single-purpose powder uses pumpkin and carrot—whole food sources of fiber—to naturally regulate digestion and create healthy stools without added probiotics or enzymes.
Poop Fixer takes a back-to-basics approach with pumpkin and carrot powder providing natural, gentle fiber. Pumpkin has long been recommended by veterinarians for digestive support—it helps firm up loose stools while also easing constipation. The 13.4 oz container provides excellent value and works for both dogs and cats. For pet parents who prefer whole-food supplements over complex formulas, this delivers results.
Pros:
- Simple, natural ingredients
- Pumpkin—a vet-recommended digestive aid
- Works for diarrhea AND constipation
- Also safe for cats
Cons:
- Doesn’t include probiotics or enzymes
Best for: Pet parents preferring natural, whole-food approaches to digestive support, or dogs sensitive to probiotic supplements.
8. Probiotics for Dogs 170 Chews – Best Value
Why it stands out: At 170 chews with probiotics, prebiotics, and digestive enzymes, this formula delivers comprehensive digestive support at one of the best per-chew prices available.
This high-count container provides excellent value for pet parents needing long-term digestive support. The formula includes probiotics for gut flora, prebiotics to feed beneficial bacteria, and digestive enzymes for improved food breakdown. The bacon-flavored chews are highly palatable, making daily dosing easy. For multi-dog households or large dogs requiring higher daily doses, this value sizing makes consistent supplementation affordable.
Pros:
- Excellent per-chew value at 170 count
- Complete probiotic, prebiotic, enzyme formula
- Bacon flavor dogs love
- Addresses diarrhea, gas, and upset stomach
Cons:
- Less brand recognition than veterinary brands
Best for: Budget-conscious pet parents needing reliable, long-term digestive support.
9. Milk Thistle Liquid for Dogs – Best Liver Support
Why it stands out: Digestive health depends on liver function, and milk thistle is the gold standard for liver support. This liquid formula delivers silymarin—milk thistle’s active compound—for detoxification and digestive optimization.
The liver plays a crucial role in digestion by producing bile and processing nutrients. Milk thistle’s silymarin supports liver cell regeneration and detoxification. This liquid supplement delivers effective doses in an easy-to-administer format with natural beef flavor. It’s especially valuable for senior dogs, those on long-term medications, or dogs recovering from illness. The 2 oz bottle provides concentrated support.
Pros:
- Supports liver function essential to digestion
- Milk thistle—veterinary-recognized liver support
- Easy liquid format with beef flavor
- Safe for dogs and puppies
Cons:
- Focused specifically on liver, not comprehensive gut health
Best for: Dogs needing liver support for optimal digestion, senior dogs, or those on medications that stress the liver.
10. Anal Gland Support Chews – Best for Anal Gland Issues
Why it stands out: Anal gland problems often stem from digestive issues—when stools aren’t firm enough, glands don’t express naturally. This formula combines fiber with digestive support to address the root cause.
STRELLALAB’s Anal Gland Support tackles a common problem pet parents face: scooting, licking, and uncomfortable anal gland issues. The formula uses fiber (including pumpkin and psyllium), prebiotics, and digestive enzymes to create firmer stools that naturally express anal glands during bowel movements. The 120 chews include beet, dandelion, and other ingredients for comprehensive digestive and gland support.
Pros:
- Addresses root cause of anal gland issues
- Fiber-rich formula for firmer stools
- Includes digestive enzymes and prebiotics
- Reduces need for manual gland expression
Cons:
- Specialized formula—may not suit all digestive needs
Best for: Dogs who scoot, need frequent anal gland expression, or have recurring gland problems related to stool consistency.
How to Choose the Right Digestive Supplement for Your Dog
Key Ingredients to Look For
Probiotics are measured in CFUs (colony-forming units)—look for products with at least 1 billion CFU for maintenance, higher for therapeutic use. Multiple probiotic strains provide broader gut support. Prebiotics (FOS, inulin) feed probiotics and help them colonize. Digestive enzymes (protease, lipase, amylase) help break down proteins, fats, and carbohydrates. Fiber sources like pumpkin and psyllium support stool formation.
Size & Breed Considerations
Larger dogs generally need higher probiotic doses. Small breeds often do well with lower-CFU maintenance formulas. Dogs with sensitive stomachs may need gentler introduction regardless of size—start with half doses. Breeds prone to digestive issues (German Shepherds, Boxers, Great Danes) often benefit from ongoing daily supplementation.
Form Factor: Chews vs Powder vs Capsules vs Liquid
Chews offer convenience and palatability. Powders mix into food and often deliver higher doses more economically. Capsules can be given whole or opened and sprinkled. Liquids absorb quickly but may be messy. Probiotics are live organisms—check that the product guarantees CFUs at time of expiration, not just at manufacture.
What to Avoid
Avoid products that don’t specify probiotic strains or CFU counts. Skip formulas with excessive fillers or artificial ingredients. Be wary of probiotics stored at room temperature without guarantees of viability. Products making extreme claims about “curing” digestive diseases should be viewed skeptically—supplements support health but don’t replace veterinary care.
Signs Your Dog May Need a Digestive Supplement
- Chronic loose stools or inconsistent stool quality
- Excessive gas and bloating
- Frequent stomach gurgling or digestive sounds
- Eating grass frequently (often indicates digestive discomfort)
- Vomiting occasionally after meals
- Scooting or anal gland issues (often related to stool consistency)
- Food sensitivities or reactions to diet changes
If your dog experiences severe vomiting, bloody stool, or sudden dramatic changes in digestion, consult your veterinarian immediately rather than relying on supplements alone.
Side Effects and Safety
Digestive supplements are generally very safe, but introducing probiotics can cause temporary gas, bloating, or loose stool as gut flora adjusts—this typically resolves within 3-7 days. Starting with half doses and gradually increasing reduces these effects.
Fiber supplements can cause constipation if dogs don’t drink adequate water—ensure fresh water is always available. Dogs with compromised immune systems should only take probiotics under veterinary supervision. If your dog is on antibiotics, give probiotics at least 2 hours apart to prevent the antibiotic from killing the beneficial bacteria. Always consult your vet before starting supplements for dogs with serious health conditions.
FAQs
How many CFUs does my dog need in a probiotic?
For daily maintenance, 1-5 billion CFU is typically sufficient. Dogs with active digestive issues often benefit from higher doses of 5-10+ billion CFU. Extremely high doses (20+ billion) are sometimes used therapeutically but should be discussed with your vet.
How long until I see improvements from digestive supplements?
Many pet parents notice improved stool quality within 3-7 days. Full gut flora rebalancing can take 4-6 weeks. If you don’t see improvement after 8 weeks, consult your vet—underlying conditions may need addressing.
Can I give probiotics to my puppy?
Yes, puppies can benefit from probiotics, especially during dietary transitions or stressful periods like weaning or adoption. Choose puppy-appropriate formulas with lower doses, and consult your vet for puppies under 12 weeks old.
Should I give probiotics during or after antibiotics?
Both. During antibiotic treatment, give probiotics at least 2 hours apart from the medication. Continue probiotics for 2-4 weeks after finishing antibiotics to help repopulate beneficial gut bacteria that antibiotics may have killed.
Can digestive supplements help with food allergies?
Probiotics support gut barrier function and immune regulation, which may help dogs with food sensitivities. However, supplements don’t cure allergies—identifying and eliminating trigger foods remains essential. Supplements work best alongside proper dietary management.
My dog eats grass constantly—will probiotics help?
Grass eating often indicates digestive discomfort. Probiotics and digestive enzymes may help by improving gut comfort and food breakdown. If grass eating continues despite supplementation, consult your vet to rule out other causes.
Final Verdict
For comprehensive digestive support, we recommend STRELLALAB Probiotics + Enzymes as the best overall choice—the 180-count container delivers both probiotics and digestive enzymes at excellent value.
Dogs needing maximum probiotic potency should try VetriScience Mega Probiotic Capsules with 7.5 billion CFU per dose. For pet parents focused specifically on stool quality, Perfect Poop Digestion Supplement delivers remarkable results with its four-pronged fiber, prebiotic, probiotic, and enzyme approach.
Budget-conscious pet parents will find excellent value in Probiotics for Dogs 170 Chews, while those dealing with anal gland issues should look at STRELLALAB Anal Gland Support Chews for targeted relief.
