Best Nature Made Prenatal Vitamins
Nature Made has earned its reputation as America’s most trusted prenatal vitamin brand through decades of commitment to quality, purity, and science-backed formulations. As the number one pharmacist-recommended vitamin brand, Nature Made offers multiple prenatal options—all USP verified and designed to support both your health and your baby’s development from conception through breastfeeding. Each formula contains essential nutrients like folic acid, iron, and DHA that play critical roles in fetal growth.
This guide evaluates Nature Made’s complete prenatal lineup to help you find the perfect formula for your pregnancy journey. Every Nature Made prenatal is gluten-free, contains no synthetic FD&C dyes, and undergoes rigorous quality testing to ensure you’re getting exactly what’s on the label.
Our Top Picks at a Glance
- Best Overall: Nature Made Prenatal + DHA Softgels — Complete one-a-day nutrition
- Best Value: Nature Made Prenatal Multivitamin 250 Tablets — 8+ months for under $20
- Best Complete: Nature Made Prenatal + Choline — First trimester powerhouse
Quick Comparison
| Product | Key Ingredients | Form | Servings | Best For |
|---|---|---|---|---|
| Prenatal + DHA 60ct | Folic Acid, 200mg DHA, Iron | Softgels | 60 | All-in-one convenience |
| Prenatal Multi 250ct | 18 nutrients, No DHA | Tablets | 250 | Long-term budget value |
| Prenatal + Choline 60ct | Folic Acid, DHA, 265mg Choline | Softgel + Capsule | 60 | Early pregnancy support |
| Prenatal + DHA 110ct | 20 nutrients, 200mg DHA | Softgels | 110 | Extended 3+ month supply |
| Prenatal Multi 90ct | Folic Acid, 18 nutrients | Tablets | 90 | Pre-conception prep |
1. Nature Made Prenatal with Folic Acid + DHA — Best Overall
- Now with orange scent: Adults take one pre natal multivitamin for women daily with water and a meal for optimal absorption
- Made in USA with quality global ingredients, this Nature Made womens prenatal multivitamin supplement is gluten free and contains no synthetic FD&C dyes
- Prenatal nutritional support supplement: Contains one 60 count bottle of Nature Made Prenatal Vitamins with Folic Acid and 200 mg DHA Softgels for a 60-day supply
- Nature Made Prenatal Vitamins with DHA and prenatal Folic Acid support a baby's brain health, bone health, eye health, and nervous system development
- Get nutrients for mom's health like Magnesium and all 8 B Vitamins including Biotin
This comprehensive softgel combines all essential prenatal nutrients with brain-boosting DHA in one convenient daily dose.
Each orange-scented softgel delivers 800 mcg folic acid for neural tube development, 27 mg iron for healthy blood formation, and 200 mg DHA for baby’s brain and eye development. With all 8 B vitamins plus vitamins A, C, D, E, and K, this formula supports every stage of fetal growth. Clinical studies confirm proven absorption of both folic acid and iron, ensuring these critical nutrients reach both you and your baby.
What We Like
- Complete one-softgel daily convenience
- USP verified for quality assurance
- Orange scent minimizes fishy taste
- Clinically proven nutrient absorption
What Could Be Better
- Larger softgel may be difficult to swallow
- Missing choline (requires separate supplement)
Bottom Line: The ideal all-in-one prenatal for women who want comprehensive nutrition with DHA without multiple pills.
2. Nature Made Prenatal Multivitamin 250 Tablets — Best Value
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Get over 8 months of prenatal nutrition for less than $20—exceptional value for budget-conscious moms.
This 250-tablet bottle provides folic acid plus 17 essential vitamins and minerals including iron, vitamin D, and calcium. While it doesn’t contain DHA (which you can add separately if desired), the tablet form offers smaller size and easier swallowing than softgels. Perfect for women planning ahead or those who already take a separate omega-3 supplement.
What We Like
- Unbeatable value under $20 for 250 days
- USP verified quality
- Smaller tablets easier to swallow
- Contains bone-supporting calcium
What Could Be Better
- No DHA included (add separately)
- Large bottle size less travel-friendly
Bottom Line: The smartest choice for women on a budget who plan to supplement DHA separately or eat fatty fish regularly.
3. Nature Made Prenatal + Choline — Best Complete Formula
- Nature Made prenatal vitamins with Folic Acid now with orange scent; Adults, take one Prenatal vitamin softgel and one Choline capsule daily with water and a meal for optimal absorption
- Nature Made Prenatal Vitamins: Includes key nutrients Folic Acid, 200 mg DHA, and 265 mg Choline for baby’s brain, cognitive and spinal cord development(1)
- These Prenatal vitamins with DHA and Folic Acid plus Choline are gluten free and have no synthetic FD&C dyes; Prenatal Supplements are now FSA/HSA eligible
- Prenatal nutritional support supplement for first trimester and beyond: contains one 60 count bottle of Nature Made Prenatal Softgels + one 60 count bottle of Choline Capsules for a 60-day supply
- Specially formulated to meet the daily nutritional needs of mothers and developing baby in early pregnancy and beyond; includes nutrients for mom like Magnesium and all 8 B vitamins including Biotin
This advanced system delivers the often-missing choline alongside complete prenatal nutrition and DHA.
Each daily dose includes one prenatal softgel with 20 nutrients and 200mg DHA, plus one choline capsule providing 265mg. Since 95% of pregnant women don’t get enough choline from diet alone, and choline is critical for baby’s brain and spinal cord development, this formula fills a crucial gap. It provides 140% more choline than standard prenatals—essential during the first trimester when neural development is most rapid.
What We Like
- Includes crucial choline missing from most prenatals
- Clinically proven folic acid and iron absorption
- Supports critical early pregnancy development
- Orange-scented softgel reduces nausea
What Could Be Better
- Requires taking two pills daily
- Higher price point than basic formulas
Bottom Line: The most comprehensive Nature Made prenatal—perfect for first trimester or women trying to conceive.
4. Nature Made Prenatal + DHA 110 Softgels — Best Extended Supply
- Now with orange scent: Adults take one pre natal multivitamin for women daily with water and a meal for optimal absorption
- Made in USA with quality global ingredients, this Nature Made womens prenatal multivitamin supplement is gluten free and contains no synthetic FD&C dyes
- Prenatal nutritional support supplement: Contains one 110 count bottle of Nature Made Prenatal Vitamins with Folic Acid and 200 mg DHA Softgels for a 110-day supply
- Nature Made Prenatal Vitamins with DHA and prenatal Folic Acid support a baby's brain health, bone health, eye health, and nervous system development
- Get nutrients for mom's health like Magnesium and all 8 B Vitamins including Biotin
Nearly 4 months of complete prenatal nutrition with better per-serving value.
This 110-count bottle offers the same comprehensive formula as the 60-count but provides better value for long-term use. Each softgel contains folic acid, 200mg DHA, iron, and all essential prenatal vitamins and minerals. The larger size means fewer pharmacy trips and consistent support throughout your pregnancy journey—ideal for women planning for full-term pregnancy.
What We Like
- Better per-serving value
- Nearly 4 months supply
- Same trusted complete formula
- FSA/HSA eligible
What Could Be Better
- Larger upfront investment
- May expire before use if pregnancy is shorter
Bottom Line: The value choice for women planning full-term pregnancy who want to stock up on complete nutrition.
5. Nature Made Prenatal Multivitamin 90 Tablets — Best Pre-Conception
- These Nature Made prenatals for women are gluten-free and contain no artificial flavors
- Prenatal nutritional support supplement: Contains one 90 count bottle of Nature Made Prenatal Vitamins with Folic Acid tablets for a 90-day supply
- This Nature Made women's multivitamin is a prenatal vitamin supplement with prenatal Folic Acid to support a baby's brain health, bone health, eye health, and nervous system
- Adults take one of these Nature Made prenatal vitamins for women tablets daily with water and a meal
- Get nutrients for mom’s health like Magnesium and all 8 B Vitamins including Biotin in these prenatal vitamins for women
Begin building nutritional reserves 3 months before conception with this perfectly-sized supply.
Healthcare experts recommend starting prenatal vitamins 3 months before trying to conceive since the neural tube forms by day 28—before most women know they’re pregnant. This 90-tablet formula provides folic acid and 17 nutrients to optimize your body for pregnancy. The 3-month supply perfectly covers the recommended pre-conception preparation period.
What We Like
- Perfect 3-month pre-conception supply
- USP verified quality
- Easy-to-swallow tablets
- Budget-friendly for planning stages
What Could Be Better
- No DHA included
- May need to switch formulas once pregnant
Bottom Line: Ideal for women in the planning stages building healthy nutrient levels before conceiving.
6. Nature Made Prenatal + DHA 90 Softgels — Best Trimester Supply
- For a limited time, you may receive either bottle while we update our packaging. Both have the same great product inside. Based on new FDA regulations, you may also notice a change in the unit of measure and/or daily value for certain products.
- Contains a 60-day supply of Nature Made Prenatal Vitamin + DHA Softgels, 60 softgels per bottle
- Specially formulated to support the development of baby’s brain, nervous system, bones and eyes. Clinically proven absorption of folic acid and iron.
- Adults, take 1 softgel daily with water and a meal for optimal absorption
Three months of comprehensive nutrition perfectly portioned for one trimester.
As baby grows, nutritional demands increase—especially for DHA which accumulates rapidly in baby’s brain during the third trimester. This 90-softgel bottle provides exactly 3 months of support with folic acid, 200mg DHA, iron, calcium, and full spectrum vitamins. The clinically proven absorption ensures nutrients effectively reach both you and baby.
What We Like
- Perfect one-trimester supply
- Clinically proven nutrient absorption
- Supports rapid third trimester brain growth
- Orange scent for easier taking
What Could Be Better
- Requires reordering every 3 months
- Softgel size challenging late in pregnancy
Bottom Line: Great for women in second or third trimester who prefer consistent 3-month supplies.
7. Nature Made Prenatal + DHA 150 Softgels — Best Value Size
- Nature Made Prenatal + DHA 150 count
Five months of complete prenatal support with maximum convenience and value.
This 150-count bottle offers the best per-serving value in Nature Made’s prenatal line. With 20 key nutrients including folic acid, DHA, and iron, it provides everything needed from conception through pregnancy. The larger size reduces reordering hassles, and the softgel format ensures optimal absorption of fat-soluble vitamins and omega-3s.
What We Like
- Best value per serving
- Five months supply
- Complete nutrition in one softgel
- USP verified quality
What Could Be Better
- Highest upfront cost
- Large bottle less travel-friendly
Bottom Line: The ultimate value for women committed to high-quality prenatal nutrition throughout pregnancy.
How to Choose
Selecting the right Nature Made prenatal starts with your pregnancy stage and nutritional priorities. If you’re trying to conceive or in early pregnancy, prioritize formulas with folic acid and strongly consider the Prenatal + Choline version since choline is critical during first trimester neural development. The 800 mcg folic acid in all Nature Made prenatals meets recommended intake for neural tube defect prevention.
Decide whether you want DHA included or prefer taking it separately. The softgel formulas with DHA provide 200 mg per serving—meeting expert recommendations for pregnancy. DHA is essential for baby’s brain and eye development with benefits continuing through breastfeeding. However, if you regularly eat fatty fish or take a separate omega-3 supplement, the tablet-only formulas offer better value and smaller pill size.
Consider your supplement tolerance and morning sickness status. If experiencing nausea, the orange-scented softgels may be easier to take than unscented tablets. However, if you struggle with large pills, the smaller tablets work better despite lacking DHA. Taking any prenatal with food helps reduce nausea and improves absorption.
Evaluate your budget and reordering preferences. The 250-tablet bottle provides exceptional long-term value for budget-conscious planning. For those past morning sickness wanting to reduce reordering frequency, the 110 and 150-count softgel bottles work well. The 60 and 90-count options suit women who prefer smaller supplies or are in early pregnancy.
Don’t overlook choline if you’re in first trimester or planning pregnancy. Most prenatals lack adequate choline, but it’s crucial for spinal cord and brain development. The Nature Made Prenatal + Choline addresses this gap, providing 265 mg (about 49% of the recommended 550 mg daily intake) alongside complete prenatal nutrition—making it worth the extra investment during early pregnancy.
Benefits
Nature Made prenatal vitamins provide comprehensive nutritional support crucial for both maternal health and fetal development throughout pregnancy. Folic acid, present in every formula at 800 mcg, dramatically reduces neural tube defect risk like spina bifida when taken before and during early pregnancy. Since the neural tube closes by day 28 (often before pregnancy awareness), starting prenatals before conception provides optimal protection.
Iron supplementation becomes critical as blood volume expands nearly 50% during pregnancy. Nature Made prenatals provide 27 mg iron per serving, supporting healthy red blood cell formation and oxygen delivery to your baby. Clinical studies demonstrate Nature Made’s iron formulation has proven absorption, helping prevent iron deficiency anemia that affects many pregnant women and can cause fatigue, weakness, and delivery complications.
DHA, the omega-3 fatty acid in Nature Made’s softgel formulas, accumulates in baby’s brain and eyes during third trimester and continues supporting development through the first year. Research shows adequate DHA intake during pregnancy associates with improved cognitive development, better vision, and enhanced problem-solving skills in children. The 200 mg dose aligns with American Pregnancy Association recommendations.
The comprehensive vitamin and mineral profile supports multiple pregnancy health aspects. Vitamin D partners with calcium to build baby’s bones and teeth while maintaining your bone density. B vitamins help convert food into energy, combating pregnancy fatigue. Vitamin C aids iron absorption and supports immune function. Vitamin A supports healthy eye development, while vitamin E provides antioxidant protection for both mother and baby.
Frequently Asked Questions
When should I start taking Nature Made prenatal vitamins?
Begin taking prenatal vitamins at least 3 months before trying to conceive. The neural tube forms during the first month of pregnancy, often before you know you’re pregnant, so having adequate folic acid levels beforehand provides the best protection against birth defects. If you’re already pregnant and haven’t started prenatals, begin immediately. Nature Made prenatal vitamins are safe throughout pregnancy and while breastfeeding.
Can I take Nature Made prenatal vitamins if I’m not pregnant?
Yes, prenatal vitamins are safe for non-pregnant women and provide comprehensive nutrition. However, the higher iron content (27 mg) may be more than non-pregnant women need. If you’re not pregnant or trying to conceive, a standard women’s multivitamin might be more appropriate. Consult your healthcare provider about the best option for your specific needs.
Should I take prenatal vitamins with food or on an empty stomach?
Take Nature Made prenatal vitamins with food and water for optimal absorption. Food helps your body absorb fat-soluble vitamins (A, D, E, K) and the DHA in softgel formulas. Taking prenatals with food also reduces stomach upset likelihood, particularly important during morning sickness. Many women find taking their prenatal with breakfast works well since B vitamins provide an energy boost.
Why do I feel nauseous after taking my prenatal vitamin?
Nausea from prenatal vitamins usually results from the iron content. Try taking your prenatal with food, particularly something with protein or healthy fats. Taking it before bed instead of morning may help, though energy-boosting B vitamins might interfere with sleep for some women. If nausea persists, talk to your healthcare provider about splitting the dose or switching formulas.
Do I need additional supplements with Nature Made prenatal vitamins?
The comprehensive formulas with DHA provide most nutrients needed during pregnancy. However, you may need additional supplements depending on your situation. If you choose the tablet-only formula, add a DHA supplement. Consider extra choline unless taking the Prenatal + Choline formula. Some healthcare providers recommend additional vitamin D, especially in northern climates or with limited sun exposure. Always consult your provider before adding supplements.
Can I take Nature Made prenatal vitamins while breastfeeding?
Yes, continue taking prenatal vitamins while breastfeeding. Your nutritional needs remain elevated during breastfeeding as you’re providing all nutrition for your baby. The folic acid, iron, DHA, and other nutrients in Nature Made prenatals support both your recovery from pregnancy and your baby’s growth through breast milk. Some women switch to postnatal formulas, but prenatal vitamins work fine for breastfeeding.
Are Nature Made prenatal vitamins safe for vegetarians?
Nature Made prenatal softgels contain gelatin (derived from animal sources), making them unsuitable for vegetarians. However, the tablet formulas are vegetarian-friendly. Check specific product labels to confirm, but generally tablets don’t contain animal-derived ingredients while softgels do. If you follow a strict vegetarian or vegan diet, tablet formulas are your best option, though you’ll need to supplement DHA separately.
How do Nature Made prenatal vitamins compare to prescription prenatals?
Nature Made prenatal vitamins contain the same key nutrients as prescription prenatals but are available over-the-counter at lower cost. The primary difference is prescription prenatals may contain higher doses of certain nutrients or different forms (like methylfolate instead of folic acid). For most healthy pregnancies, Nature Made over-the-counter prenatals provide adequate nutrition. However, women with specific health conditions, nutrient deficiencies, or absorption issues may benefit from prescription formulas. Discuss with your healthcare provider which option is best for you.
