Best Nitric Oxide Supplements (2026) – Top 10 Reviewed
Nitric oxide supplements have become essential for athletes, gym-goers, and anyone looking to support healthy blood flow and cardiovascular function. These formulas use ingredients like beet root, L-arginine, and L-citrulline to help your body produce more nitric oxide—a molecule that relaxes blood vessels and improves circulation.
The best options combine proven vasodilators with good bioavailability and clean ingredients. Here are our top 10 picks for 2026.
| Product | Key Ingredients | Servings | Form | Best For |
|---|---|---|---|---|
| Beet Root Gummies with COQ10 & Pomegranate | Beet Root, CoQ10, Pomegranate | 60 | Gummies | Best Overall |
| Sugar Free Beet Root Gummies | Beet Root, Coconut Oil | 60 | Gummies | Best Sugar-Free |
| Snap Supplements Organic Beet Root Powder | Organic Beet Root, Pomegranate | 30 | Powder | Best Organic Powder |
| L-Arginine with L-Citrulline Capsules (120ct) | L-Arginine, L-Citrulline | 60 | Capsules | Best Amino Acid Blend |
| M inch Beet Root 8-in-1 Gummies | Beet Root, Grape Seed, CoQ10, B Vitamins | 60 | Gummies | Best Multi-Ingredient |
| Cayenne Pepper Circulation Softgels | Cayenne, Beetroot, D3+K2, CoQ10 | 240 | Softgels | Best for Leg Circulation |
| L-Arginine with L-Citrulline (60ct) | L-Arginine 1000mg, L-Citrulline | 60 | Capsules | Best Budget Option |
| Nitric Oxide Gummies with Beet Root | L-Arginine, Beet Root | 90 | Gummies | Best Unique Flavor |
| Beet Root Gummies with COQ10 (30ct) | Beet Root, CoQ10, Pomegranate | 30 | Gummies | Best Trial Size |
| Snap Supplements Beet Root Powder Cherry Lime | Organic Beet Root, Pomegranate | 30 | Powder | Best Tasting Powder |
1. Beet Root Gummies with COQ10 & Pomegranate – Best Overall
Why it stands out: This formula combines three powerful circulation-supporting ingredients in a convenient gummy format. The addition of CoQ10 provides cellular energy support while pomegranate adds extra antioxidant protection.
Each serving delivers a potent dose of beet root extract, which the body converts to nitric oxide through the nitrate-nitrite pathway. The CoQ10 supports energy production in cells, making this an excellent choice for both workout performance and daily cardiovascular support. At 120 gummies per bottle, you get a full two-month supply. The mixed berry flavor makes these easy to take consistently without the earthy taste of straight beet powder.
Pros:
- Triple-action formula with beet root, CoQ10, and pomegranate
- 60-day supply per bottle
- Vegan and non-GMO certified
- Pleasant mixed berry taste
Cons:
- Contains added sugars (2g per serving)
Best for: Anyone wanting a comprehensive nitric oxide supplement that also supports cellular energy.
2. Sugar Free Beet Root Gummies – Best Sugar-Free
Why it stands out: These gummies deliver nitric oxide support without the added sugars found in most gummy supplements. The coconut oil infusion enhances absorption of the beet root compounds.
The formula uses concentrated beet root extract paired with coconut oil, which helps improve the bioavailability of the nitrate compounds. This is particularly important since fat-soluble compounds absorb better with dietary fat present. The 120-count bottle provides a 60-day supply, and the strawberry flavor masks the earthy beet taste effectively. Being sugar-free makes these ideal for those watching carbohydrate intake or following keto and low-sugar diets.
Pros:
- Zero sugar per serving
- Coconut oil enhances absorption
- 60-day supply
- Keto-friendly
Cons:
- Contains sugar alcohols which may cause digestive discomfort in sensitive individuals
Best for: Keto dieters, diabetics, or anyone avoiding added sugars while wanting nitric oxide support.
3. Snap Supplements Organic Beet Root Powder – Best Organic Powder
Why it stands out: USDA-certified organic beet root powder with added pomegranate provides a whole-food approach to nitric oxide support. The powder format allows for flexible dosing and mixing.
This powder contains only organic beet root and pomegranate—no fillers, artificial ingredients, or additives. You can mix it into water, smoothies, or pre-workout drinks. The 8.8 oz container provides a full month of daily servings. Organic certification ensures the beets were grown without synthetic pesticides or fertilizers, which matters since beets can accumulate chemicals from soil. The mixed berry flavoring makes it more palatable than unflavored beet powders.
Pros:
- USDA organic certified
- Versatile powder format
- No artificial ingredients
- Pomegranate adds antioxidant benefits
Cons:
- Requires mixing (less convenient than gummies or capsules)
Best for: Those who prefer whole-food supplements and want control over dosing.
4. L-Arginine with L-Citrulline Capsules (120ct) – Best Amino Acid Blend
Why it stands out: This formula uses the direct precursor pathway to nitric oxide production. L-arginine converts directly to nitric oxide while L-citrulline recycles back to L-arginine, creating sustained production.
Unlike beet-based products that rely on the nitrate pathway, this supplement uses amino acids that your body converts to nitric oxide through the L-arginine-NO synthase pathway. The combination of both amino acids is key—L-citrulline has better oral bioavailability than L-arginine alone and helps maintain elevated arginine levels for longer. The 120-capsule bottle provides a two-month supply at the standard dose. Vegan capsules make this suitable for plant-based diets.
Pros:
- Uses direct amino acid pathway to nitric oxide
- L-citrulline improves L-arginine absorption
- 2-month supply
- Vegan and non-GMO
Cons:
- Requires taking 2 capsules per serving
Best for: Athletes and fitness enthusiasts who want the amino acid approach to nitric oxide support.
5. M inch Beet Root 8-in-1 Gummies – Best Multi-Ingredient
Why it stands out: This comprehensive formula combines beet root with seven additional ingredients including grape seed extract, CoQ10, and B vitamins for broad cardiovascular and energy support.
The 8-in-1 formula addresses circulation from multiple angles. Beet root provides nitrates, grape seed extract supports blood vessel health, CoQ10 aids cellular energy, and B vitamins (B3, B12, and folic acid) support overall cardiovascular function. Vitamin C rounds out the formula as an antioxidant that helps protect nitric oxide from degradation. The sugar-free formulation and pomegranate flavor make these a practical daily option. This two-pack provides excellent value for those committed to long-term use.
Pros:
- Comprehensive 8-ingredient formula
- Sugar-free
- Includes B vitamins for added cardiovascular support
- Two-pack offers good value
Cons:
- Complex formula means lower doses of individual ingredients
Best for: Those wanting broad cardiovascular support beyond just nitric oxide.
6. Cayenne Pepper Circulation Softgels – Best for Leg Circulation
Why it stands out: This unique formula combines cayenne pepper with beetroot and multiple circulation-supporting compounds specifically designed for leg vein health and peripheral circulation.
Cayenne pepper contains capsaicin, which stimulates circulation and blood flow throughout the body. Combined with beetroot for nitric oxide support, plus vitamin D3+K2 for vascular health, this creates a comprehensive circulation formula. The addition of berberine, CoQ10, omega-3, turmeric, and hawthorn provides anti-inflammatory and antioxidant benefits. At 240 softgels per bottle, this offers excellent value. The softgel format also makes the cayenne easier on the stomach than raw powder.
Pros:
- Targets peripheral circulation specifically
- 240-count bottle (4-month supply)
- Multiple synergistic ingredients
- Softgels are easy to swallow
Cons:
- Large number of ingredients means lower individual doses
- May cause warmth or flushing from cayenne
Best for: Those specifically concerned about leg circulation, cold extremities, or vein health.
7. L-Arginine with L-Citrulline (60ct) – Best Budget Option
Why it stands out: This smaller-count version of the amino acid blend provides an affordable entry point to try the L-arginine/L-citrulline combination without a larger commitment.
The formula delivers 1,000mg of L-arginine combined with L-citrulline per serving—the same proven combination as the larger bottle at a lower upfront cost. This one-month supply lets you evaluate how your body responds to amino acid-based nitric oxide support before investing in larger quantities. The vegan capsules and non-GMO certification maintain quality despite the budget-friendly positioning. This is also a practical option for occasional use, such as taking only before workouts.
Pros:
- Lower upfront cost
- Same formula as larger bottle
- Good for testing response
- Full 1,000mg L-arginine dose
Cons:
- Higher per-serving cost than bulk options
- Only 1-month supply
Best for: First-time buyers wanting to try amino acid NO supplements, or occasional users.
8. Nitric Oxide Gummies with Beet Root – Best Unique Flavor
Why it stands out: These gummies combine L-arginine with beet root in a distinctive green apple and cinnamon flavor that stands apart from typical berry-flavored supplements.
This formula takes a dual-pathway approach by including both L-arginine (direct conversion) and beet root (nitrate pathway) for nitric oxide production. The 90-count bottle provides a one-month supply at 3 gummies per day. The green apple and cinnamon flavor is refreshingly different from the typical mixed berry options that dominate the market. Cinnamon also has its own circulation-supporting properties, adding a functional element to the flavoring choice.
Pros:
- Dual-pathway formula (amino acid + nitrate)
- Unique, pleasant flavor profile
- Vegan and non-GMO
- Cinnamon adds functional benefits
Cons:
- 3 gummies per serving is more than some competitors
- Flavor may not appeal to everyone
Best for: Those who dislike berry flavors or want both nitric oxide pathways in one supplement.
9. Beet Root Gummies with COQ10 (30ct) – Best Trial Size
Why it stands out: This smaller bottle uses the same proven formula as our top pick, making it perfect for trying the product before committing to the larger size.
With the same beet root, CoQ10, and pomegranate combination as the 120-count version, this 30-count bottle provides a two-week supply at the standard dose. This is ideal for first-time buyers who want to ensure they tolerate the ingredients and enjoy the taste before purchasing larger quantities. The formula, taste, and quality are identical to the full-size product—you’re simply getting less of it. It’s also useful for travel or keeping a backup supply.
Pros:
- Same quality formula as full-size
- Lower initial investment
- Good for travel
- Tests tolerance before bulk purchase
Cons:
- Higher cost per gummy than larger bottle
- Only 2-week supply
Best for: First-time buyers testing the product, or travelers needing a compact option.
10. Snap Supplements Beet Root Powder Cherry Lime – Best Tasting Powder
Why it stands out: This organic beet powder offers a refreshing cherry lime flavor that’s notably different from the typical berry options, making daily consumption more enjoyable.
Same organic beet root and pomegranate formula as the mixed berry version, but with a brighter, more citrus-forward flavor profile. The cherry lime combination effectively masks the earthy beet taste that some people find off-putting. The powder mixes well with cold water and can also be added to smoothies or juices. One 8.8 oz container provides 30 servings for a full month of use. For those who’ve tried beet supplements before but couldn’t tolerate the taste, this flavor option is worth exploring.
Pros:
- Refreshing citrus flavor
- USDA organic certified
- Same quality as mixed berry version
- Mixes easily
Cons:
- Some may prefer berry flavors
- Requires daily mixing
Best for: Those who prefer citrus flavors or have been put off by typical beet supplement tastes.
What is Nitric Oxide and Who Should Take It?
Nitric oxide (NO) is a gas molecule your body produces naturally that signals blood vessels to relax and dilate. This vasodilation improves blood flow throughout your body, supporting everything from exercise performance to cardiovascular health to cognitive function.
Your body produces nitric oxide through two main pathways: the L-arginine pathway (using the amino acid L-arginine) and the nitrate-nitrite-NO pathway (using dietary nitrates from foods like beets). Supplements target one or both of these pathways. Athletes often use NO supplements for improved workout performance and recovery, while others take them for general cardiovascular support, blood pressure management, or improved circulation to extremities.
How to Choose the Right Nitric Oxide Supplement
Key Ingredients to Look For
The most effective nitric oxide supplements use either beet root extract (providing dietary nitrates), L-arginine, L-citrulline, or combinations of these. Beet root products should specify the nitrate content or use concentrated extracts. For amino acid supplements, look for at least 1,000mg of L-arginine and the inclusion of L-citrulline, which improves absorption and extends the duration of effect. Supporting ingredients like CoQ10, pomegranate, and grape seed extract can enhance the overall cardiovascular benefits.
Forms Compared
Powders offer flexible dosing and often the highest doses per serving, but require mixing. Gummies provide convenience and taste benefits but may contain added sugars. Capsules are convenient and sugar-free but require swallowing multiple pills for effective doses. Softgels work well for fat-soluble ingredient combinations and are easy to take.
What to Avoid
Steer clear of products with proprietary blends that don’t disclose individual ingredient amounts. Avoid supplements with excessive fillers, artificial colors, or ingredients you don’t recognize. For beet-based products, ensure they use beet root extract rather than just beet fiber, which doesn’t provide the nitrate benefits.
Side Effects and Precautions
Nitric oxide supplements are generally well-tolerated. Common side effects are mild and include digestive upset, headaches, or flushing—particularly with higher doses or when first starting. Beet-based supplements may cause red or pink urine (beeturia), which is harmless.
If you take blood pressure medications, blood thinners, or erectile dysfunction drugs, consult your doctor before starting a nitric oxide supplement, as these can interact. Those with low blood pressure should use caution since NO supplements can further reduce blood pressure. Pregnant or nursing women should consult a healthcare provider before use.
FAQs
How much L-arginine should I take for nitric oxide benefits? Most research uses doses between 2,000-6,000mg daily, though benefits can be seen at lower doses, especially when combined with L-citrulline. Start with the manufacturer’s recommended dose and adjust based on your response.
When should I take nitric oxide supplements? For exercise performance, take your supplement 30-60 minutes before your workout. For general cardiovascular support, consistent daily timing matters more than specific timing. Some people prefer morning doses to support energy throughout the day.
How long does it take to notice effects from nitric oxide supplements? Acute effects on exercise performance can be noticed within the first few uses. General cardiovascular benefits typically develop over 2-4 weeks of consistent use. Beet-based products may show effects faster than amino acid supplements.
Can I take nitric oxide supplements with pre-workout? Yes, many pre-workout formulas already contain NO-boosting ingredients. Check your pre-workout label for L-arginine, L-citrulline, or beet root to avoid doubling up on doses. If your pre-workout lacks these, adding a separate NO supplement is fine.
Are beet supplements or amino acid supplements better for nitric oxide? Both work through different pathways and can be effective. Beet root works through dietary nitrates and may show effects quickly. L-arginine and L-citrulline work directly but require consistent dosing. Some people respond better to one pathway than the other, and combination products target both.
Do nitric oxide supplements help with blood pressure? Some research suggests NO supplements can modestly support healthy blood pressure levels already in the normal range. However, if you have hypertension or take blood pressure medication, consult your doctor before use—the blood pressure-lowering effects could interact with your treatment.
Final Verdict
For most people, the Beet Root Gummies with COQ10 & Pomegranate offer the best combination of effectiveness, convenience, and value. The triple-ingredient formula supports nitric oxide production while providing additional cardiovascular benefits from CoQ10 and pomegranate.
If you prefer sugar-free options or follow a keto diet, the Sugar Free Beet Root Gummies deliver comparable benefits without the carbs. For those who want the amino acid approach, the L-Arginine with L-Citrulline Capsules provide a proven combination at a competitive price.
Athletes may benefit most from the Snap Supplements Organic Beet Root Powder, which allows for flexible pre-workout dosing.
