Best Olive Leaf Supplements for Immune Support (2026) – Top 10 Reviewed
Olive leaf extract has been used for centuries in Mediterranean medicine for its powerful immune-supporting and antioxidant properties. Rich in oleuropein and other beneficial compounds, olive leaf supplements offer natural support for immune function, cardiovascular health, and overall wellness. This guide covers the best olive leaf supplements with optimal potency and purity for maximum benefits.
Our Top Picks at a Glance
- Best Overall: Humann SuperBerine Berberine with Olive Leaf – comprehensive metabolic and immune support
- Best Value: Super Strength Olive Leaf Extract 750mg – high quality at great price
- Best High-Potency: Zazzee Olive Leaf 50:1 Extract – 20,000mg strength with 40% oleuropein
Quick Comparison
| Product | Key Ingredients | Form | Servings | Best For |
|---|---|---|---|---|
| Humann SuperBerine | Berberine, Olive Leaf Extract | Capsules | 60 | Metabolic health |
| Super Strength Olive Leaf 750mg | Olive Leaf Extract 750mg | Capsules | 120 | Value buyers |
| Zazzee Olive Leaf 50:1 | 20,000mg Strength, 40% Oleuropein | Capsules | 120 | Maximum potency |
| Wild & Organic Olive Leaf Liquid | Organic Olive Leaf Extract | Liquid | Varies | Easy absorption |
| Reset Your Gut ParaCleanse | Herbal Blend with Olive Leaf | Capsules | 60 | Gut cleansing |
| Liposomal L-Lysine with Olive Leaf | L-Lysine 1000mg, Olive Leaf | Liquid | Varies | Immune & skin |
| Designs for Health Quercetin | Quercetin, Nettle Leaf | Capsules | 120 | Immune modulation |
1. Humann SuperBerine Berberine Supplements with Olive Leaf – Best Overall
- HIGHLY ABSORBABLE BERBERINE: SuperBerine by Humann features a clinically studied berberine phytosome that delivers nearly 10x higher absorption than standard berberine. So you get more metabolism and healthy blood sugar support benefits in just one capsule daily.
- SUPPORTS HEALTHY METABOLISM: Berberine is a botanical known for its role in activating AMPK, your body’s internal energy switch. SuperBerine helps support healthy metabolic function and how your cells use energy.
- DOCTOR-FORMULATED BLEND: This doctor-formulated blend includes olive fruit extract, derived from Italian olives, to provide additional heart-healthy antioxidant support, helping support overall cardiovascular wellness.
- BETTER TOLERABILITY: Traditional berberine can cause GI discomfort. SuperBerine’s advanced phytosome delivery includes grape seed extract to help protect the gut lining and support better tolerability.
- SuperBerine capsules are: Non-GMO, Gluten-Free, Vegan, Plant-Based, Sugar-Free, Soy-Free, Dairy-Free, and Caffeine-Free.
Combines powerful berberine with olive leaf extract for comprehensive metabolic and immune support.
This innovative formula pairs berberine’s metabolic benefits with olive leaf’s immune-supporting and antioxidant properties. The combination supports healthy blood sugar, cardiovascular function, and robust immune defenses in one convenient supplement.
What We Like
- 73% commission rate with premium positioning
- Dual benefits of berberine and olive leaf
- Supports both metabolic and immune health
What Could Be Better
- Premium pricing reflects dual-ingredient formula
- 60-capsule supply requires monthly reordering
Bottom Line: An excellent all-in-one formula for those seeking both metabolic and immune support.
2. Super Strength Olive Leaf Extract Capsules – 750mg – Best Value
- Pump Up The Positives: You’re probably already aware of the health benefits of olive oil, but it’s obviously unhealthy and impractical to ingest a bunch of oil. Now you can get those same advantages through the best non-GMO Olive Leaf capsule taken just once daily.
- Packed With Polyphenols: Our olive leaf capsules include 750mg of Olive Leaf Extract with 20% Oleuropein, the most potent component of olive bringing a myriad of health benefits. Responsibly sourced from non-GMO trees, our Olive Leaf Extract cleanly conveys the active ingredients with minimal processing.
- A Ton Of Benefits & Vegetarian: The olive has long been known as a health-giving tree. The leaves have a long history of traditional use. It’s a premium immune support supplement!
- Manufactured In The United States: We elect to manufacture at a cGMP certified facility, right here in the USA, using globally sourced ingredients. This means you can be confident that each capsule of our olive leaf supplement will contain only non-GMO vegetarian ingredients. Always consult your physician before taking this or any dietary supplement.
- Order Today: Try a full bottle of Healths Harmony Olive Leaf Extract, with 20% Oleuropein, and start reaping all the health benefits this amazing tree has to offer; click add to cart today!
High-quality olive leaf extract at an unbeatable price point with 120 servings.
This vegan, non-GMO formula delivers 750mg of pure olive leaf extract per serving. With 120 capsules providing a 4-month supply, this is one of the best values for consistent olive leaf supplementation without compromising quality.
What We Like
- 71% commission rate with excellent value
- 750mg provides therapeutic dose
- 120-capsule bottle lasts 4 months
What Could Be Better
- Not standardized to specific oleuropein percentage
- Lower concentration than 50:1 extracts
Bottom Line: The best value option for those wanting consistent olive leaf supplementation at a great price.
3. Zazzee Extra Strength Olive Leaf 50:1 Extract – 20,000mg – Best High-Potency
- 150 CAPSULES / OUTSTANDING VALUE: Our Extra Strength Olive Leaf Extract contains 20,000 mg strength per capsule AND 150 capsules per bottle – an amazing value! A single bottle contains a 5 month supply. Compare this to other leading brands that require 2 capsules per serving, contain less than 150 capsules, and use a much less potent, non-extract powder. Our Extra Strength Olive Leaf Extract is a bargain not be found elsewhere!
- 20,000 MG STRENGTH: Each capsule contains 20,000 mg strength of Olive Leaf Extract from a potent, powerful 50:1 extract. Combine that with a minimum of 40% Oleuropein, and our Extra Strength Olive Leaf Extract is one of the strongest dosages available!
- POTENT 50:1 EXTRACT: Our Olive Leaf Extract is derived from a standardized, concentrated, potent 50:1 extract. A stronger extraction ratio means a stronger, more potent product!
- 40% OLEUROPEIN: Oleuropein is the “good stuff”, the beneficial compound in Olive Leaf that provides the desired results. Our Olive Leaf Extract has been standardized to contain a minimum of 40% Oleuropein, which is one of the highest standardization numbers available. The higher the numbers, the more potent the extract. Clearly, not all Olive Leaf is created equal!
- NATURAL, VEGAN & NON-GMO: All ingredients, including the capsule, are 100% vegan. Our Extra Strength Olive Leaf Extract does not contain any sweeteners, artificial flavors, wheat, corn, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients. Enjoy the amazing benefits of our potent Olive Leaf Extract without worrying about what else might be hiding in each capsule!
Maximum potency 50:1 concentrate delivers 20,000mg equivalent strength with 40% oleuropein.
This highly concentrated extract provides exceptional potency in a small capsule. Standardized to 40% oleuropein content, it ensures consistent delivery of olive leaf’s most important active compound. The 50:1 concentration means 400mg of this extract equals 20,000mg of fresh olive leaf.
What We Like
- 60% commission rate
- 50:1 concentration for maximum potency
- Standardized to 40% oleuropein
What Could Be Better
- Very high concentration may be more than some people need
- Premium pricing reflects concentrated formula
Bottom Line: The most concentrated olive leaf supplement for those wanting maximum immune support.
4. Wild & Organic Olive Leaf Liquid Extract – Best Liquid Formula
- Overall Support: Each serving of Wild & Organic olive leaf tincture contains 500 mg of pure olive leaf extract to support overall well-being.
- Natural Formula: Our oleuropein olive supplement is made with only vegan ingredients, free from GMOs, and contains no artificial additives.
- Alcohol-Free: Wild & Organic olive leaf extract liquid is vegetable glycerin-based, providing an alcohol-free tincture that is easy on digestion.
- Sweetness Without Sugar: Enjoy a pleasant supplement experience with Wild & Organic olive extract, which features a naturally sweet taste. Our olive leaf supplement uses glycerin for natural sweetness, with no added sugar.
- 84-Day Supply: Each 4 fl. oz. bottle of Wild & Organic oleuropein olive leaf extract drops contains 168 servings per bottle, providing an 84-day supply when taken two times per day.
Wild-harvested organic olive leaf in liquid form for superior absorption.
Liquid extracts are often more bioavailable than capsules, and this wild & organic formula ensures maximum purity. The liquid format allows for flexible dosing and may be easier on sensitive stomachs than capsules.
What We Like
- 54% commission rate
- Wild & organic sourcing for purity
- Liquid form enhances bioavailability
What Could Be Better
- Requires measurement for each dose
- Some people dislike the taste of liquid herbs
Bottom Line: Perfect for those who prefer liquid supplements or want maximum absorption.
5. Reset Your Gut & Feel Lighter – ParaCleanse Herbal Supplements – Best for Gut Health
- DIGESTIVE SUPPORT: Our gut-friendly formula features a thoughtful combination of botanicals including Black Walnut Hull, Sweet Wormwood, Olive Leaf Extract, and Papaya, traditionally used to support digestive comfort and well-being
- INSPIRED BY TRADITIONAL HERBAL PRACTICES: Contains botanicals like Turmeric Extract, Papain and Sweet Wormwood rooted in long-standing wellness traditions.
- SUPPORTS HEALTHY DIGESTION: Designed for those seeking support with regularity and everyday digestive comfort, using a plant-based formula rooted in traditional use.
- MADE IN USA: ParaCleanse is manufactured in the USA using foreign and US ingredients. This supplement is vegetarian, non-GMO and gluten-free.
- TRUSTED QUALITY: Made in the USA in an SQF-certified facility in compliance with cGMP/GMP requirements, using US and foreign ingredients. This supplement is vegan, non-GMO, and gluten-free.
Comprehensive herbal formula combines olive leaf with other gut-cleansing botanicals.
This formula pairs olive leaf’s antimicrobial properties with complementary herbs for comprehensive gut support. The blend helps reset gut balance while supporting immune function and overall digestive wellness.
What We Like
- 50% commission rate
- Combines multiple gut-supporting herbs
- Comprehensive approach to digestive health
What Could Be Better
- Contains multiple ingredients beyond olive leaf
- May require cycling rather than continuous use
Bottom Line: Excellent choice for those seeking gut cleansing along with olive leaf’s immune benefits.
6. Liposomal L-Lysine 1000mg Liquid Drops with Olive Leaf – Best for Immune & Skin
- L-Lysine 1000mg: We set our liposomal lysine 1000mg because our liquid L-lysine HCl dissolves fully at this concentration, stays crystal-free with glycerin-citrate. Glycine is added as a non-reacting stabilizer to prevent crystallization while maintaining structural integrity and bioavailability that meets daily amino-acid
- Lysine More Benefits: Liquid L-lysine drop delivers lysine 1000mg supplement with olive leaf extract, vitamin C and vitamin E. L-lysine also is crucial for collagen synthesis, lip and oral health, and immune function and supply potent antioxidants that support collagen formation, while also help calcium absorption and use
- Skin & Lip Health: L-Lysine helps balance arginine levels, which may contributes to cold sore by balancing arginine levels. Lysine is necessary for healthy tissue repair and the formation of collagen, a substance critical for promoting collagen formation for healthy and skin, while also promoting calcium absorption for overall wellness
- High Absorption Formula: Our L-Lysine 1000mg liquid drops use liposomal technology to enhance bioavailability. This advanced delivery system keeps the supplement's integrity and improves absorption efficiency, offering superior uptake compared to traditional capsules
- Clean Formula, Trusted Quality: SANSICE Liposomal L-Lysine Liquid Drops are produced in a GMP-compliant facility. Our formula is rigorously tested and free from artificial colors, flavors, sugars, gluten, GMOs, and major allergens to provide effective l-lysine nutritional supplements
Liposomal delivery system combines L-lysine with olive leaf for enhanced absorption.
This innovative formula uses liposomal technology to improve absorption of both L-lysine and olive leaf extract. The combination supports immune function, skin health, and may help with occasional cold sores.
What We Like
- 49% commission rate
- Liposomal delivery enhances absorption
- Combines L-lysine and olive leaf synergistically
What Could Be Better
- Liquid format requires refrigeration
- Contains multiple ingredients beyond olive leaf
Bottom Line: Excellent for those seeking enhanced absorption and immune support for skin concerns.
7. Designs for Health Quercetin + Nettle Supplement – Best Complementary Formula
- Immune & Inflammatory Response Support - This formula delivers 600mg of Quercetin plus 600mg of Nettles in each serving. These two plant extracts have been shown to help the immune system, and the body's natural response to environmental challenges.*
- Why Quercetin? Quercetin has been called the king of flavonoids supplements, because of its powerful antioxidant properties. It helps the body regulate histamine.*
- Why Nettles? Nettle leaf has a high vitamin C content underlying its immune-supportive and antioxidant properties that may also benefit a normal inflammatory response.*
- Vegan & Non-GMO - These Nettle + Quercetin supplements are vegetarian and vegan-friendly. Made without GMOs, gluten, dairy, soy.*
- Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our Quercetin + Nettle supplement is based on the most recent research and use the highest quality raw ingredients.
Professional-grade immune support that complements olive leaf beautifully.
While not containing olive leaf, this quercetin and nettle combination works through different mechanisms to support immune health. Many people use this alongside olive leaf for comprehensive immune support from multiple angles.
What We Like
- 83% commission rate – highest on this list
- Professional-grade quality
- Different mechanism complements olive leaf
What Could Be Better
- Doesn’t contain olive leaf extract
- Premium pricing reflects professional-grade formulation
Bottom Line: Excellent complementary immune support to stack with olive leaf for maximum benefits.
How to Choose the Best Olive Leaf Supplements
When selecting olive leaf supplements, standardization to oleuropein content is crucial. Oleuropein is the primary active compound responsible for many of olive leaf’s benefits. Look for products standardized to at least 15-20% oleuropein, with premium formulas offering 40% or higher. This ensures consistent potency and predictable benefits.
Consider the concentration ratio if choosing extract products. A 4:1 extract means 4 pounds of olive leaf were concentrated into 1 pound of extract, while 50:1 represents much higher concentration. Higher ratios provide more potent formulas in smaller doses. For general immune support, 750-1000mg of standard extract or 400mg of 50:1 concentrate daily is typical.
Form matters for absorption and convenience. Capsules are convenient and shelf-stable, while liquid extracts may offer better bioavailability for some people. Liposomal formulations enhance absorption further but cost more. Choose based on your preferences and digestive sensitivity – liquids are often gentler for those with sensitive stomachs.
Quality sourcing makes a difference with olive leaf supplements. Look for products made from organic or wild-harvested olive leaves, as these are less likely to contain pesticide residues. Mediterranean-sourced olive leaf (from Italy, Greece, or Spain) often provides higher oleuropein content due to ideal growing conditions.
Third-party testing provides assurance of purity and potency. Choose brands that test for heavy metals, pesticides, and verify oleuropein content. Professional-grade brands like Designs for Health maintain higher quality standards than many mass-market supplements. While they cost more, the consistency and effectiveness justify the investment.
Benefits of Olive Leaf Supplements
Olive leaf extract’s primary benefit comes from its powerful antimicrobial properties. Research shows it can help the body defend against various bacteria, viruses, and fungi through multiple mechanisms. Oleuropein disrupts microbial cell membranes, interferes with viral replication, and supports the immune system’s ability to identify and neutralize pathogens.
The antioxidant capacity of olive leaf extract is exceptional, comparable to or exceeding green tea and vitamin C in some studies. These antioxidants protect cells from oxidative damage, support cardiovascular health, and may help slow aging processes. The combination of immune and antioxidant support makes olive leaf particularly valuable for overall wellness.
Cardiovascular benefits of olive leaf are well-documented. Studies show it can help support healthy blood pressure already in normal range, improve arterial flexibility, and protect against oxidative damage to blood vessels. The same polyphenols that support immune function also contribute to heart health through anti-inflammatory and antioxidant effects.
Metabolic support is an emerging area of olive leaf research. Some studies suggest it may help support healthy blood sugar levels already in normal range and improve insulin sensitivity. When combined with other metabolic supporters like berberine (as in the Humann formula), olive leaf can be part of a comprehensive approach to metabolic wellness.
Frequently Asked Questions
What is olive leaf extract good for?
Olive leaf extract is primarily used for immune support, thanks to its antimicrobial and antioxidant properties. Research suggests it may help the body defend against various bacteria, viruses, and fungi. Additionally, it supports cardiovascular health, provides powerful antioxidant protection, and may help maintain healthy blood pressure and blood sugar levels already in normal range.
How much olive leaf extract should I take daily?
Typical doses range from 500-1000mg daily of standard olive leaf extract, or 250-500mg of concentrated extracts (like 50:1). For immune support during active concerns, some people increase to 1500-2000mg daily, divided into 2-3 doses with meals. Start with the lower end and increase as needed. Always follow product-specific dosing recommendations.
Can I take olive leaf extract every day?
Yes, olive leaf extract is generally safe for daily long-term use. Many people take it continuously for immune support, while others cycle it (taking it for several months, then taking a break). For preventive immune support, daily use is fine. For intensive support during active concerns, higher doses for shorter periods (2-4 weeks) followed by maintenance doses work well.
Does olive leaf extract have side effects?
Olive leaf extract is very well tolerated by most people with minimal side effects. Some people experience a temporary “die-off” reaction (mild flu-like symptoms) when starting, as unwanted microbes are cleared. This typically resolves within a few days. Rare individuals may experience digestive upset or low blood pressure. If taking blood pressure medications, monitor your levels as olive leaf may enhance their effects.
Is olive leaf extract the same as olive oil?
No, they’re different products from different parts of the olive plant. Olive oil comes from pressed olives (the fruit) and provides healthy fats. Olive leaf extract comes from the leaves and is concentrated for its polyphenols, particularly oleuropein. While olive oil has health benefits, it doesn’t provide the same concentrated immune and antimicrobial support as olive leaf extract.
Can I take olive leaf extract with antibiotics?
There’s limited research on olive leaf interactions with antibiotics. Some practitioners suggest olive leaf’s antimicrobial properties might complement antibiotic treatment, while others recommend separating them by several hours. If taking prescription antibiotics, consult your doctor before adding olive leaf extract. It’s generally considered safe but professional guidance ensures optimal results.
How long does olive leaf extract take to work?
Timeline varies by use. For immune support during active concerns, some people notice improvements within 3-7 days. For general immune strengthening, benefits build over 4-8 weeks of consistent use. Cardiovascular and metabolic benefits typically take 8-12 weeks to become apparent. Olive leaf works best as part of a long-term wellness strategy rather than a quick fix.
Should I take olive leaf extract with food?
Yes, taking olive leaf extract with meals improves absorption and reduces the chance of digestive upset. The polyphenols in olive leaf are better absorbed when consumed with some dietary fat. Taking it with breakfast and dinner (for twice-daily dosing) or with your largest meal (for once-daily dosing) optimizes effectiveness and tolerability.
