Best Prenatal Vitamins Nature Made
Nature Made has earned its position as America’s number one prenatal vitamin brand through decades of trusted quality and USP verification. Whether you’re trying to conceive, newly pregnant, or in your third trimester, Nature Made offers multiple prenatal formulations to meet your specific nutritional needs. Their prenatal vitamins deliver essential nutrients like folic acid, iron, and DHA that support both your health and your baby’s development.
We’ve evaluated Nature Made’s complete prenatal line to help you choose the right formula for your stage of pregnancy. All Nature Made prenatals are USP verified, gluten-free, and contain no synthetic FD&C dyes, giving you peace of mind about quality and purity.
Our Top Picks at a Glance
- Best Overall: Nature Made Prenatal with Folic Acid + DHA — Complete nutrition in one softgel
- Best Value: Nature Made Prenatal Multivitamin Tablets — Affordable long-term supply
- Best Advanced: Nature Made Prenatal + Choline — Comprehensive first trimester support
Quick Comparison
| Product | Key Ingredients | Form | Servings | Best For |
|---|---|---|---|---|
| Prenatal + DHA 60ct | Folic Acid, 200mg DHA, Iron | Softgels | 60 | All-in-one convenience |
| Prenatal Multi 250ct | Folic Acid, 18 nutrients | Tablets | 250 | Long-term value |
| Prenatal + Choline | Folic Acid, DHA, 265mg Choline | Softgel + Capsule | 60 | Early pregnancy |
| Prenatal + DHA 110ct | 20 key nutrients, 200mg DHA | Softgels | 110 | Extended supply |
| Prenatal Folic Acid 90ct | 800mcg Folic Acid | Tablets | 90 | Pre-conception |
1. Nature Made Prenatal with Folic Acid + DHA 60 Softgels — Best Overall
- Now with orange scent: Adults take one pre natal multivitamin for women daily with water and a meal for optimal absorption
- Made in USA with quality global ingredients, this Nature Made womens prenatal multivitamin supplement is gluten free and contains no synthetic FD&C dyes
- Prenatal nutritional support supplement: Contains one 60 count bottle of Nature Made Prenatal Vitamins with Folic Acid and 200 mg DHA Softgels for a 60-day supply
- Nature Made Prenatal Vitamins with DHA and prenatal Folic Acid support a baby's brain health, bone health, eye health, and nervous system development
- Get nutrients for mom's health like Magnesium and all 8 B Vitamins including Biotin
This all-in-one softgel combines essential prenatal nutrition with DHA in a convenient once-daily formula.
Each softgel delivers 800 mcg of folic acid (reducing neural tube defect risk), 200 mg of DHA for baby’s brain and eye development, and 27 mg of iron for healthy blood formation. The formula includes all 8 B vitamins plus vitamins A, C, D, E, and K. The orange-scented softgel makes it more pleasant to take, especially important if you’re experiencing morning sickness. Clinical studies show clinically proven absorption of both folic acid and iron.
What We Like
- Complete nutrition in one convenient softgel
- USP verified for quality and purity
- Orange scent reduces fishy aftertaste
- Includes optimal 200mg DHA dose
What Could Be Better
- Larger softgel size may be hard to swallow
- No choline (needs separate supplement)
Bottom Line: The ideal choice for women who want comprehensive prenatal nutrition with DHA in a single, convenient softgel.
2. Nature Made Prenatal Multivitamin with Folic Acid 250 Tablets — Best Value
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Get more than 8 months of prenatal nutrition at an unbeatable price.
This 250-tablet bottle provides folic acid plus 17 other essential prenatal vitamins and minerals including iron, vitamin D, and calcium. The tablet form contains no DHA (which you can supplement separately if desired), making it a cost-effective option for long-term prenatal support. Each tablet is easy to swallow and contains everything you need for baby’s brain, nervous system, bone, and eye development.
What We Like
- Exceptional value at under $19 for 250 days
- USP verified quality
- Smaller tablet easier to swallow than softgels
- Contains calcium for bone health
What Could Be Better
- No DHA included (must supplement separately)
- Large bottle size less portable
Bottom Line: Perfect for budget-conscious moms-to-be who plan to supplement DHA separately.
3. Nature Made Prenatal Vitamin Softgels + Choline Capsules — Best Advanced Formula
- Nature Made prenatal vitamins with Folic Acid now with orange scent; Adults, take one Prenatal vitamin softgel and one Choline capsule daily with water and a meal for optimal absorption
- Nature Made Prenatal Vitamins: Includes key nutrients Folic Acid, 200 mg DHA, and 265 mg Choline for baby’s brain, cognitive and spinal cord development(1)
- These Prenatal vitamins with DHA and Folic Acid plus Choline are gluten free and have no synthetic FD&C dyes; Prenatal Supplements are now FSA/HSA eligible
- Prenatal nutritional support supplement for first trimester and beyond: contains one 60 count bottle of Nature Made Prenatal Softgels + one 60 count bottle of Choline Capsules for a 60-day supply
- Specially formulated to meet the daily nutritional needs of mothers and developing baby in early pregnancy and beyond; includes nutrients for mom like Magnesium and all 8 B vitamins including Biotin
This comprehensive system delivers folic acid, DHA, and the often-overlooked choline for optimal early pregnancy support.
Each daily dose includes one prenatal softgel with 20 key nutrients and 200mg DHA, plus one choline capsule providing 265mg. Choline is critical for baby’s brain and spinal cord development, yet 95% of pregnant women don’t get enough from diet alone. The formula provides 140% more choline per dose than standard prenatals, making it ideal for first trimester when baby’s neural development is most rapid.
What We Like
- Includes crucial choline often missing from prenatals
- Clinically proven absorption of folic acid and iron
- Supports critical first trimester development
- Orange-scented softgel reduces nausea
What Could Be Better
- Requires taking two separate pills daily
- Higher price point
Bottom Line: The most comprehensive Nature Made prenatal for women in early pregnancy or trying to conceive.
4. Nature Made Prenatal with Folic Acid + DHA 110 Softgels — Best Extended Supply
- Now with orange scent: Adults take one pre natal multivitamin for women daily with water and a meal for optimal absorption
- Made in USA with quality global ingredients, this Nature Made womens prenatal multivitamin supplement is gluten free and contains no synthetic FD&C dyes
- Prenatal nutritional support supplement: Contains one 110 count bottle of Nature Made Prenatal Vitamins with Folic Acid and 200 mg DHA Softgels for a 110-day supply
- Nature Made Prenatal Vitamins with DHA and prenatal Folic Acid support a baby's brain health, bone health, eye health, and nervous system development
- Get nutrients for mom's health like Magnesium and all 8 B Vitamins including Biotin
Nearly 4 months of complete prenatal nutrition in one convenient bottle.
This 110-count softgel offers the same comprehensive formula as the 60-count version but provides better value for long-term use. Each softgel contains folic acid, 200mg DHA, iron, and all essential prenatal vitamins and minerals. The larger size means fewer trips to the pharmacy and consistent prenatal support throughout pregnancy. Ideal for women who want to stock up and save.
What We Like
- Better per-serving value than smaller bottles
- Nearly 4 months supply
- Same trusted formula as smaller size
- FSA/HSA eligible
What Could Be Better
- Larger upfront investment
- May expire before use if pregnancy is short
Bottom Line: The smart choice for women planning for full-term pregnancy who want the best value on complete prenatal nutrition.
5. Nature Made Prenatal Multivitamin with Folic Acid 90 Tablets — Best for Pre-Conception
- These Nature Made prenatals for women are gluten-free and contain no artificial flavors
- Prenatal nutritional support supplement: Contains one 90 count bottle of Nature Made Prenatal Vitamins with Folic Acid tablets for a 90-day supply
- This Nature Made women's multivitamin is a prenatal vitamin supplement with prenatal Folic Acid to support a baby's brain health, bone health, eye health, and nervous system
- Adults take one of these Nature Made prenatal vitamins for women tablets daily with water and a meal
- Get nutrients for mom’s health like Magnesium and all 8 B Vitamins including Biotin in these prenatal vitamins for women
Start building your nutritional foundation before pregnancy with this folic acid-rich formula.
Experts recommend beginning prenatal vitamins 3 months before conception since the neural tube forms by day 28 of gestation, before many women know they’re pregnant. This 90-tablet formula provides folic acid and 17 other nutrients to prepare your body for pregnancy. The tablet form is easy to take daily, and the 3-month supply perfectly covers the pre-conception preparation period.
What We Like
- Perfect 3-month pre-conception supply
- USP verified quality
- Easy-to-swallow tablets
- Budget-friendly for pre-pregnancy planning
What Could Be Better
- No DHA included
- May need to switch to DHA formula once pregnant
Bottom Line: Ideal for women in the planning stages who want to establish healthy nutrient levels before conceiving.
6. Nature Made Prenatal with Folic Acid + DHA 90 Softgels — Best for Second/Third Trimester
- For a limited time, you may receive either bottle while we update our packaging. Both have the same great product inside. Based on new FDA regulations, you may also notice a change in the unit of measure and/or daily value for certain products.
- Contains a 60-day supply of Nature Made Prenatal Vitamin + DHA Softgels, 60 softgels per bottle
- Specially formulated to support the development of baby’s brain, nervous system, bones and eyes. Clinically proven absorption of folic acid and iron.
- Adults, take 1 softgel daily with water and a meal for optimal absorption
Three months of comprehensive nutrition to support your growing baby.
As your baby grows, nutritional demands increase, especially for DHA which accumulates rapidly in baby’s brain during the third trimester. This 90-softgel bottle provides exactly 3 months of daily support with folic acid, 200mg DHA, iron, calcium, and full spectrum vitamins. The clinically proven absorption ensures nutrients reach both you and baby effectively.
What We Like
- Perfect for one trimester
- Clinically proven nutrient absorption
- Supports rapid brain growth in third trimester
- Orange scent for easier taking
What Could Be Better
- Need to reorder every 3 months
- Softgel size may be challenging late in pregnancy
Bottom Line: An excellent choice for women in their second or third trimester who want consistent 3-month supplies.
7. Nature Made Prenatal + DHA 150 Softgels — Best for Long-Term Planning
- Nature Made Prenatal + DHA 150 count
Five months of complete prenatal support with maximum convenience.
This 150-count bottle offers the best per-serving value in Nature Made’s prenatal line. With 20 key nutrients including folic acid, DHA, and iron, it provides everything needed for baby’s development from conception through pregnancy. The larger size reduces the hassle of frequent reordering, and the softgel format ensures optimal absorption of fat-soluble vitamins and omega-3s.
What We Like
- Best value per serving
- Five months supply reduces reordering
- Complete nutrition in one softgel
- USP verified quality
What Could Be Better
- Highest upfront cost
- Large bottle less travel-friendly
Bottom Line: The ultimate value for women committed to high-quality prenatal nutrition throughout pregnancy.
8. Nature Made Prenatal Folic Acid Tablets 90 Count — Best Standalone Folic Acid
- DAILY ADVANTAGE: Each tablet contains 800 mcg of folic acid making it easy and hassle-free
- EARLY PROTECTION: Adequate folic acid intake before and during pregnancy helps reduce the risk of defects
- SIMPLE AND EFFECTIVE: Makes it easy to integrate essential prenatal support into your routine without unnecessary ingredients
- SCIENCE-BACKED: Committed to quality and purity, this is USP Verified, ensuring you receive a potent and reliable dose with every tablet
- MADE FOR YOU: Gluten-free and free from artificial flavors and colors, this option caters to diverse needs and preferences
Targeted folic acid support for women who need extra neural tube defect protection.
Some women require higher folic acid doses, particularly those with a family history of neural tube defects or certain genetic variants. These tablets deliver 800 mcg of folic acid in a simple, easy-to-take formula. You can pair them with your regular multivitamin or take alone if you’re already eating a nutrient-rich diet but need folic acid insurance.
What We Like
- Focused folic acid supplementation
- Small, easy-to-swallow tablets
- Can combine with other supplements flexibly
- USP verified
What Could Be Better
- Missing other prenatal nutrients
- Requires separate multivitamin and DHA
Bottom Line: Best for women who need targeted folic acid support and prefer building their own supplement regimen.
How to Choose
Selecting the right Nature Made prenatal depends on your pregnancy stage, nutritional needs, and supplement preferences. If you’re trying to conceive or in early pregnancy, prioritize formulas with folic acid and consider adding the choline version since choline is critical during the first trimester when the neural tube develops. The 800 mcg of folic acid in all Nature Made prenatals meets the recommended daily intake for preventing neural tube defects.
Consider whether you want DHA included or prefer taking it separately. The softgel formulas with DHA provide 200 mg per serving, which meets expert recommendations for pregnancy. DHA is an omega-3 fatty acid essential for baby’s brain and eye development, with benefits continuing through breastfeeding. However, if you eat fatty fish regularly or take a separate omega-3 supplement, the tablet-only formulas might be sufficient and offer better value.
Think about your supplement tolerance and preferences. If you experience morning sickness, the orange-scented softgels may be easier to take than unscented tablets. However, if you struggle with large pills, the smaller tablets might work better despite lacking DHA. Some women find taking supplements with food helps reduce nausea, which works well with all Nature Made prenatals.
Evaluate your timeline and budget. If you’re planning ahead, the 250-tablet bottle provides exceptional long-term value. For those in early pregnancy, the 60 or 90-count options offer good starter supplies. The 110 and 150-count softgel bottles work well for women who’ve moved past morning sickness and want to reduce reordering frequency.
Don’t forget about choline if you’re in the first trimester or planning pregnancy. Most prenatals don’t include adequate choline, but it’s crucial for spinal cord development and brain growth. The Nature Made Prenatal + Choline formula addresses this gap, providing 265 mg of choline (about 49% of the recommended 550 mg daily intake during pregnancy) alongside complete prenatal nutrition.
Benefits
Taking Nature Made prenatal vitamins provides comprehensive nutritional support for both mother and baby throughout pregnancy. Folic acid, the star ingredient in every prenatal formula, dramatically reduces the risk of neural tube defects like spina bifida when taken before and during early pregnancy. Since the neural tube closes by day 28 of gestation (often before women realize they’re pregnant), starting prenatals before conception provides optimal protection.
Iron supplementation becomes critical during pregnancy as your blood volume expands by nearly 50%. Nature Made prenatals provide 27 mg of iron per serving, supporting healthy red blood cell formation and oxygen delivery to your baby. Clinical studies demonstrate that Nature Made’s iron formulation has proven absorption, helping prevent the iron deficiency anemia that affects many pregnant women and can lead to fatigue, weakness, and complications during delivery.
DHA, the omega-3 fatty acid included in Nature Made’s softgel formulas, accumulates in your baby’s brain and eyes during the third trimester and continues supporting development through the first year of life. Research shows that adequate DHA intake during pregnancy is associated with improved cognitive development, better vision, and enhanced problem-solving skills in children. The 200 mg dose in Nature Made prenatals aligns with expert recommendations from the American Pregnancy Association.
The comprehensive vitamin and mineral profile supports multiple aspects of pregnancy health. Vitamin D partners with calcium to build your baby’s bones and teeth while maintaining your own bone density. B vitamins help convert food into energy, combating pregnancy fatigue. Vitamin C aids iron absorption and supports immune function. Vitamin A supports healthy eye development, while vitamin E provides antioxidant protection for both mother and baby.
Frequently Asked Questions
When should I start taking prenatal vitamins?
Begin taking prenatal vitamins at least 3 months before trying to conceive. The neural tube forms during the first month of pregnancy, often before you know you’re pregnant, so having adequate folic acid levels beforehand provides the best protection against birth defects. If you’re already pregnant and haven’t started prenatals yet, begin immediately. Nature Made prenatal vitamins are safe to take throughout pregnancy and while breastfeeding.
Can I take Nature Made prenatal vitamins if I’m not pregnant?
Yes, prenatal vitamins are safe for non-pregnant women and provide comprehensive nutrition. However, the higher iron content (27 mg) in prenatal formulas may be more than non-pregnant women need. If you’re not pregnant or trying to conceive, a standard women’s multivitamin might be more appropriate. Consult your healthcare provider about the best option for your specific needs.
Should I take the prenatal vitamin with food or on an empty stomach?
Take Nature Made prenatal vitamins with food and water for optimal absorption. Food helps your body absorb fat-soluble vitamins (A, D, E, K) and the DHA in softgel formulas. Taking prenatals with food also reduces the likelihood of stomach upset, particularly important if you’re experiencing morning sickness. Many women find taking their prenatal with breakfast works well since the B vitamins provide an energy boost for the day.
Why do I feel nauseous after taking my prenatal vitamin?
Nausea from prenatal vitamins usually results from the iron content. Try taking your prenatal with food, particularly something with protein or healthy fats. Taking it before bed instead of morning may help, though the energy-boosting B vitamins might interfere with sleep for some women. If nausea persists, talk to your healthcare provider about whether splitting the dose or switching to a different formula might help.
Do I need to take additional supplements with Nature Made prenatal vitamins?
The comprehensive formulas with DHA provide most nutrients needed during pregnancy. However, you may need additional supplements depending on your specific situation. If you choose the tablet-only formula, add a DHA supplement. Consider adding extra choline unless you’re taking the Prenatal + Choline formula. Some healthcare providers recommend additional vitamin D, especially if you live in northern climates or have limited sun exposure. Always consult your provider before adding supplements.
Can I take Nature Made prenatal vitamins while breastfeeding?
Yes, continue taking prenatal vitamins while breastfeeding. Your nutritional needs remain elevated during breastfeeding as you’re providing all nutrition for your baby. The folic acid, iron, DHA, and other nutrients in Nature Made prenatals support both your recovery from pregnancy and your baby’s growth through breast milk. Some women switch to a postnatal formula, but prenatal vitamins work fine for breastfeeding as well.
Are Nature Made prenatal vitamins safe for vegetarians?
Nature Made prenatal softgels contain gelatin (derived from animal sources), making them unsuitable for vegetarians. However, the tablet formulas are vegetarian-friendly. Check the specific product label to confirm, but generally, tablets don’t contain animal-derived ingredients while softgels do. If you follow a strict vegetarian or vegan diet, the tablet formulas are your best option, though you’ll need to supplement DHA separately.
How do Nature Made prenatal vitamins compare to prescription prenatals?
Nature Made prenatal vitamins contain the same key nutrients as prescription prenatals but are available over-the-counter at a lower cost. The primary difference is that prescription prenatals may contain higher doses of certain nutrients or different forms (like methylfolate instead of folic acid). For most healthy pregnancies, Nature Made over-the-counter prenatals provide adequate nutrition. However, women with specific health conditions, nutrient deficiencies, or absorption issues may benefit from prescription formulas. Discuss with your healthcare provider which option is best for you.
