Best Supplements for Chihuahuas (2026) – Top 10 Reviewed

Chihuahuas may be tiny, but they have unique health needs that the right supplements can support. From their delicate joints and bones to their fast metabolisms and sensitive digestive systems, these pint-sized pups benefit from targeted nutritional support throughout their lives.

The best Chihuahua supplements use appropriately-sized doses, easy-to-chew formats, and high-quality ingredients without unnecessary fillers. Small breed dogs also tend toward dental issues and hypoglycemia, so multivitamins and digestive support are particularly valuable. Here are our top 10 picks for 2026.

ProductKey Ingredients/FeaturesCountFormBest For
VetriScience 27+ Active Health Chews27+ Nutrients, Omegas, Antioxidants60ChewsBest Overall
BARK&SPARK Dog Allergy Relief ChewsOmega 3, Probiotics, Colostrum120ChewsBest for Skin & Coat
Bark&Spark Glucosamine ChondroitinGlucosamine, Chondroitin, MSM120ChewsBest for Joint Support
STRELLALAB Dog Probiotics ChewsProbiotics, Enzymes, Prebiotics120ChewsBest for Digestion
Wagmee Allergy Relief DropsFish Oil, Omega 3, Vitamin E2 ozLiquidBest Liquid Option
VetriScience Calm & Confident ChewsL-Theanine, Colostrum, Thiamine30ChewsBest for Anxiety
20-in-1 Dog Multivitamin ChewsGlucosamine, Probiotics, Omega 3120ChewsBest Value
VetriScience Gut Health ChewsProbiotics, Prebiotics, Pumpkin30ChewsBest for Sensitive Stomachs
Milk Thistle for Dogs LiquidMilk Thistle, Liver Support2 ozLiquidBest for Liver Support
Melatonin for Dogs Sleep AidMelatonin 6mg, Calming Blend90TreatsBest Budget Calming

1. VetriScience 27+ Active Health Chews – Best Overall

Why it stands out: This comprehensive daily multivitamin delivers 27+ essential nutrients specifically formulated for dogs of all sizes, making it ideal for Chihuahuas who need complete nutritional support in a small, chewable format.

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VetriScience has built a reputation for veterinary-strength formulas, and this multivitamin lives up to that standard. It includes omega fatty acids for skin and coat health, antioxidants for immune support, and a full spectrum of vitamins and minerals. The soft chew format is easy for small mouths to handle, and the taste is palatable enough that most Chihuahuas take them willingly. At one chew daily for dogs under 30 lbs, a single container lasts two months.

Pros:

  • Comprehensive 27+ nutrient formula
  • Veterinarian-formulated
  • Soft, small chews perfect for toy breeds
  • Made in USA with quality ingredients

Cons:

  • Premium price point

Best for: Chihuahua owners wanting complete daily nutritional coverage in one supplement.


2. BARK&SPARK Dog Allergy Relief Chews – Best for Skin & Coat

Why it stands out: Chihuahuas are prone to skin sensitivities and allergies, and this formula combines omega-3 fatty acids with probiotics and colostrum to address itching, dry skin, and coat health from multiple angles.

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This supplement tackles skin issues both internally and externally. The omega-3s support healthy skin cell function while probiotics promote gut health, which directly impacts skin condition. Colostrum provides immune support that helps dogs better handle environmental allergens. The chews are sized appropriately for small dogs, and the 120-count container offers excellent value for ongoing maintenance.

Pros:

  • Multi-action formula for skin and coat
  • Contains probiotics for gut-skin connection
  • Omega-3 rich for anti-inflammatory benefits
  • High count provides lasting supply

Cons:

  • May take 4-6 weeks to see full results

Best for: Chihuahuas with itchy skin, seasonal allergies, or dull coats.


3. Bark&Spark Glucosamine Chondroitin – Best for Joint Support

Why it stands out: Despite their small size, Chihuahuas can develop patellar luxation and joint issues. This joint supplement provides glucosamine, chondroitin, and MSM to support cartilage health and mobility throughout their long lifespans.

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Chihuahuas often live 15+ years, making joint support particularly important as they age. This formula delivers clinically-studied joint ingredients in a tasty soft chew that small dogs readily accept. The combination of glucosamine for cartilage support, chondroitin for joint cushioning, and MSM for inflammation support covers all bases. Dosing is weight-based, so a container lasts longer for toy breeds.

Pros:

  • Complete joint support formula
  • Soft chews easy for small mouths
  • Appropriate dosing for toy breeds
  • Supports long-term mobility

Cons:

  • Chews may be slightly large for very tiny Chihuahuas

Best for: Senior Chihuahuas or those showing early signs of joint stiffness.


4. STRELLALAB Dog Probiotics Chews – Best for Digestion

Why it stands out: Chihuahuas are notorious for sensitive stomachs, and this probiotic formula combines beneficial bacteria with digestive enzymes to support healthy gut function and reduce gas, diarrhea, and digestive upset.

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Digestive issues are among the most common complaints from Chihuahua owners. This supplement provides multiple probiotic strains to populate the gut with beneficial bacteria, plus enzymes that help break down food more efficiently. The prebiotics feed the good bacteria to help them thrive. Many owners report seeing improvements in stool quality and reduced gas within the first week of use.

Pros:

  • Multi-strain probiotic formula
  • Includes digestive enzymes
  • Fast-acting for acute issues
  • Helps with gas and loose stools

Cons:

  • Requires daily consistency for best results

Best for: Chihuahuas with sensitive stomachs, frequent gas, or inconsistent stool quality.


5. Wagmee Allergy Relief Drops – Best Liquid Option

Why it stands out: For Chihuahuas who refuse chews or have difficulty with solid supplements, this liquid formula delivers fish oil and omega-3s directly onto food for easy administration.

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Liquid supplements offer precise dosing control, which matters for tiny dogs where even small variations can be significant. This formula provides fish oil rich in EPA and DHA, plus vitamin E for antioxidant support. Simply add drops to your Chihuahua’s food based on their weight. The fish flavor is typically well-accepted, and you avoid any concerns about chew size or texture preferences.

Pros:

  • Precise dosing for tiny dogs
  • Easy to add to any food
  • No chewing required
  • High-quality omega fatty acids

Cons:

  • Fish smell may be off-putting to some owners

Best for: Picky Chihuahuas who won’t take chews or very small dogs needing precise dosing.


6. VetriScience Calm & Confident Chews – Best for Anxiety

Why it stands out: Chihuahuas are known for their big personalities and occasional nervousness. This clinically-tested calming formula uses L-theanine and colostrum to promote relaxation without sedation.

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Many Chihuahuas struggle with separation anxiety, fear of strangers, or stress during thunderstorms and travel. This supplement works with your dog’s natural brain chemistry to promote calm behavior without causing drowsiness. The L-theanine promotes relaxation, colostrum supports stress response, and thiamine aids nervous system function. Can be given daily for ongoing anxiety or as-needed for stressful events.

Pros:

  • Clinically tested ingredients
  • Non-sedating formula
  • Can use daily or situationally
  • Small chew size appropriate for toy breeds

Cons:

  • May need to double dose for high-stress situations

Best for: Anxious Chihuahuas dealing with separation anxiety, travel stress, or general nervousness.


7. 20-in-1 Dog Multivitamin Chews – Best Value

Why it stands out: This comprehensive formula packs 20 different health-supporting ingredients into one affordable supplement, making it an excellent entry point for Chihuahua owners wanting broad nutritional support.

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Getting great value doesn’t mean sacrificing quality. This multivitamin includes glucosamine for joints, probiotics for digestion, omega fatty acids for skin and coat, plus vitamins and minerals for overall health. The 120-count container at a competitive price point means you get months of supplementation for your Chihuahua. The soft chews are appropriately sized and flavored for good acceptance.

Pros:

  • 20 active ingredients in one supplement
  • Excellent price per serving
  • Covers multiple health areas
  • High count container

Cons:

  • May not be as potent as targeted single-purpose supplements

Best for: Budget-conscious owners wanting comprehensive nutritional support for their Chihuahua.


8. VetriScience Gut Health Chews – Best for Sensitive Stomachs

Why it stands out: This everyday probiotic formula is specifically designed for dogs with chronic digestive sensitivity, using gentle ingredients that won’t further upset delicate stomachs.

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Some Chihuahuas need gentler digestive support than high-potency formulas provide. VetriScience’s everyday gut health chews deliver a balanced blend of probiotics and prebiotics without overwhelming sensitive systems. The inclusion of pumpkin provides natural fiber support. This formula works well for maintenance after resolving acute digestive issues or for dogs who react poorly to stronger probiotics.

Pros:

  • Gentle formula for sensitive dogs
  • Contains soothing pumpkin
  • Everyday maintenance dosing
  • Veterinary-strength brand

Cons:

  • Lower probiotic count than intensive formulas

Best for: Chihuahuas with chronic digestive sensitivity who need gentle, ongoing support.


9. Milk Thistle for Dogs Liquid – Best for Liver Support

Why it stands out: Chihuahuas metabolize medications differently than larger dogs, making liver support particularly important. This liquid milk thistle supplement supports healthy liver function and detoxification.

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Milk thistle has been used for centuries to support liver health, and this liquid formula makes dosing easy for small dogs. The liver plays a crucial role in processing everything from food to medications, and Chihuahuas’ small size means their livers work hard relative to their body weight. This supplement provides targeted support for dogs on long-term medications, seniors, or those recovering from illness.

Pros:

  • Liquid format for precise small-dog dosing
  • Supports liver function naturally
  • Good for dogs on medications
  • Easy to add to food

Cons:

  • Specialized supplement rather than daily multivitamin

Best for: Chihuahuas on long-term medications or seniors needing liver support.


10. Melatonin for Dogs Sleep Aid – Best Budget Calming

Why it stands out: For Chihuahuas who struggle with sleep disruption or need occasional calming support, this melatonin-based formula offers an affordable, natural option.

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Melatonin is a naturally occurring hormone that regulates sleep-wake cycles, and supplementing can help dogs who experience restlessness at night or anxiety-related sleep issues. This formula provides 6mg melatonin in a treat format that’s easy to dose for small dogs. It’s particularly useful for travel, thunderstorms, or helping senior Chihuahuas maintain healthy sleep patterns.

Pros:

  • Natural sleep hormone
  • Affordable price point
  • Treat format dogs enjoy
  • Good for occasional use

Cons:

  • Not for daily long-term use without vet guidance

Best for: Chihuahuas with occasional sleep issues or situational anxiety at an affordable price.


How to Choose the Right Supplement for Your Chihuahua

Key Ingredients to Look For

Chihuahuas benefit most from supplements containing omega-3 fatty acids for skin and coat health, probiotics for their sensitive digestive systems, and glucosamine/chondroitin for joint support. Look for formulas with appropriately-sized doses since toy breeds need much less than what’s standard for larger dogs. Quality multivitamins should contain a full spectrum of vitamins A, D, E, and B-complex, plus minerals like zinc and selenium.

Size & Dosing Considerations

Always follow weight-based dosing instructions carefully. Chihuahuas typically weigh 3-6 pounds, putting them at the lowest end of most dosing charts. Some supplements designed for larger dogs may be difficult to split accurately, making small-dog-specific products or liquid formulas preferable. When in doubt, start with the lowest recommended dose and adjust based on your dog’s response.

Form Factor: Chews vs Tablets vs Liquid

Soft chews are typically the easiest format for Chihuahuas since they’re palatable and easy to consume. However, some chews designed for all dog sizes may be too large for very small Chihuahuas. Liquid supplements offer the most precise dosing control and can be mixed directly into food. Tablets and powders are options but may require crushing or measuring, adding complexity.

What to Avoid

Steer clear of supplements with artificial colors, flavors, or preservatives that can trigger sensitivities in small dogs. Avoid products with doses calculated for large breeds that can’t be safely divided. Watch out for fillers like corn, wheat, or soy if your Chihuahua has food sensitivities. Always verify the manufacturer’s quality standards and look for products made in facilities following good manufacturing practices.


Signs Your Chihuahua May Need Supplements

  • Dull or flaky coat: May indicate omega fatty acid deficiency or skin issues
  • Frequent digestive upset: Gas, loose stools, or vomiting suggest probiotic support could help
  • Stiffness after rest: Joint supplements can support mobility in aging Chihuahuas
  • Excessive scratching: Allergy support supplements may provide relief
  • Low energy levels: A comprehensive multivitamin can address nutritional gaps
  • Anxiety or nervousness: Calming supplements support stress management
  • Slow recovery from illness: Immune-supporting supplements may help

If your Chihuahua shows persistent or severe symptoms, consult your veterinarian before starting any supplement regimen.


Side Effects and Safety

Most supplements are well-tolerated by Chihuahuas when dosed appropriately. The most common side effects are mild digestive upset when first introducing a new supplement, which typically resolves within a few days. Start with half the recommended dose and gradually increase to allow your dog’s system to adjust.

Chihuahuas’ small size means they’re more sensitive to overdosing. Never exceed recommended amounts, and avoid giving multiple supplements with overlapping ingredients without veterinary guidance. If your Chihuahua takes any medications, consult your vet about potential interactions. Pregnant or nursing dogs and puppies under 12 weeks should only receive supplements under veterinary supervision.


FAQs

What supplements do Chihuahuas need most?

Chihuahuas benefit most from omega-3 fatty acids for skin and coat health, probiotics for digestive support, and joint supplements as they age. A quality multivitamin can provide baseline nutritional support, while calming supplements help with breed-typical anxiety issues.

How do I get my picky Chihuahua to take supplements?

Try liquid supplements added to wet food, or crush chews and mix with a small amount of peanut butter or cream cheese. Some owners find success hiding chews in pill pockets or soft treats. If your Chihuahua consistently refuses, switch to a different brand or format.

Can I give my Chihuahua human supplements?

No. Human supplements contain doses formulated for much larger body weights and may include ingredients toxic to dogs, like xylitol. Always use supplements specifically formulated for dogs and follow weight-based dosing instructions.

How long until I see results from supplements?

Most supplements require 4-8 weeks of consistent daily use before showing noticeable results. Joint supplements may take up to 12 weeks for full effect. Probiotics often show faster results, sometimes within 1-2 weeks for digestive improvements.

Are supplements safe for Chihuahua puppies?

Many supplements are formulated for adult dogs only. Puppies under 12 months have different nutritional needs and should receive supplements only under veterinary guidance. Most puppy-specific formulas or those labeled safe for all ages can be used with appropriate dosing.

Can I give multiple supplements at the same time?

Yes, but be cautious about overlapping ingredients that could lead to overdosing. For example, don’t combine two joint supplements both containing glucosamine. When in doubt, space supplements out or consult your veterinarian about combining products.


Final Verdict

For comprehensive daily nutrition, VetriScience 27+ Active Health Chews delivers everything most Chihuahuas need in one veterinarian-formulated supplement. The quality ingredients and appropriate sizing make it our top recommendation.

If you’re on a budget, the 20-in-1 Dog Multivitamin Chews provides solid multi-system support at an excellent price point. For specific concerns like skin allergies, the BARK&SPARK Dog Allergy Relief Chews offer targeted relief, while the STRELLALAB Dog Probiotics address the digestive sensitivity so common in this breed. Senior Chihuahuas showing joint stiffness will benefit from the Bark&Spark Glucosamine Chondroitin formula to maintain mobility through their golden years.

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