Best Vitamin K2 MK-7 Supplements (2026) – Top 10 Reviewed
Vitamin K2 MK-7 has emerged as one of the most important nutrients for bone density and cardiovascular health, with clinical research demonstrating its ability to direct calcium into bones while keeping it out of arteries. Unlike vitamin K1, the MK-7 form stays active in your body longer and offers superior bioavailability.
The best K2 supplements use the MK-7 form from natto fermentation or chickpea-derived sources like MenaQ7. Here are our top 10 picks for 2026.
| Product | Key Ingredients | Servings | Form | Best For |
|---|---|---|---|---|
| Natural Vitamin D3 K2 Gummies | 2000 IU D3, 100 mcg K2 | 60 | Gummies | Best Overall |
| Toku Flow Nattokinase + K2 | K2 MK-7, Nattokinase, Beta Glucan | 30 | Powder | Best for Circulation |
| Vitamin D3 K2 Liquid Drops | 2000 IU D3 + K2 | 900+ | Drops | Best Value |
| VITBOOST D3 K2 Complex | 5000 IU D3, 90 mcg MK-7 | 120 | Capsules | Best High-Potency |
| DaVinci Labs ADK 10 | Vitamins A, D3, K2 MK-7 | 90 | Capsules | Best ADK Formula |
| Nature’s Craft D3 with K2 MK-7 | 2000 IU D3, K2 MK-7 | 120 | Tablets | Best Budget Option |
| Vitamin D3 K2 3000 IU | 3000 IU D3, K2 MK-7 | 90 | Capsules | Best Mid-Range D3 |
| Vitamin K2 MK-7 Gummies 100mcg | 100 mcg K2 MK-7 | 60 | Gummies | Best Standalone K2 |
| Vitamin D3 5000IU + K2 + B Complex | D3, K2, B12, B6, Zinc | 60 | Gummies | Best Multi-Nutrient |
| Full Spectrum Vitamin K2 | 600 mcg K2 (MK-7 + MK-4) | 90 | Capsules | Best Full Spectrum |
1. Natural Vitamin D3 K2 Gummies – Best Overall
Why it stands out: This formula combines a clinical dose of vitamin K2 MK-7 with vitamin D3 in a tasty gummy format, making it easy to stay consistent with supplementation while supporting both bone and heart health.
Each serving delivers 2000 IU of vitamin D3 alongside 100 mcg of vitamin K2 as MK-7—the exact ratio research supports for optimal calcium metabolism. The strawberry-flavored gummies are GMO-free and gluten-free, making them accessible for most dietary needs. The combination approach means you get synergistic benefits without needing multiple supplements, simplifying your daily routine while ensuring proper calcium utilization.
The D3 component helps your body absorb calcium from food and supplements, while the K2 MK-7 activates osteocalcin and matrix GLA protein—the key proteins responsible for depositing calcium into bones and keeping it out of arteries. This synergy is why most experts now recommend taking these vitamins together rather than separately.
Pros:
- Optimal D3/K2 ratio backed by clinical research
- Tasty gummy format improves compliance
- GMO-free and gluten-free
- 60-day supply per bottle
Cons:
- Contains added sugars typical of gummy supplements
Best for: Anyone wanting an easy, effective D3+K2 combination for comprehensive bone and cardiovascular support.
2. Toku Flow Nattokinase + K2 – Best for Circulation
Why it stands out: This innovative powder formula combines vitamin K2 MK-7 with 10,800 FU of nattokinase and oat beta glucan, targeting both calcium metabolism and circulatory health in one product.
Toku Flow takes a unique approach by pairing K2 with nattokinase—an enzyme also derived from natto that supports healthy blood flow and fibrin breakdown. The soy-free formulation uses a plant-based approach with chocolate flavor, delivered in convenient single-serve packets. This makes it ideal for those focused on cardiovascular health beyond just calcium management.
The oat beta glucan adds cholesterol-supporting benefits, making this a comprehensive cardiovascular formula. Each packet dissolves easily in water or your morning smoothie. For anyone concerned about arterial health, blood flow, or overall circulatory function, this multi-action approach offers benefits that standalone K2 supplements simply can’t match. The functional powder format also appeals to those who prefer not to swallow pills.
Pros:
- Combines K2 with nattokinase for enhanced circulatory support
- Soy-free despite using natto-derived ingredients
- Single-serve packets for convenience
- Pleasant chocolate flavor
Cons:
- Premium price point
- Powder format not for everyone
Best for: Those prioritizing cardiovascular and circulatory health alongside bone support.
3. Vitamin D3 K2 Liquid Drops – Best Value
Why it stands out: With over 900 days of supply in a single bottle, these liquid drops offer unmatched value while providing precise dosing control for both adults and children.
Each drop delivers 2000 IU of vitamin D3 paired with vitamin K2 MK-7, and the liquid format allows you to adjust your dose easily. The dropper bottle design means this is one of the most economical K2 supplements available—costing just pennies per day. Liquid drops also offer faster absorption compared to capsules or tablets since they bypass the need for digestion.
The flexibility of liquid dosing is particularly valuable for families. Children may need lower doses, while some adults may want to increase their intake during winter months or if blood tests show deficiency. You can add drops to food, beverages, or take them directly under the tongue for sublingual absorption. The 1-ounce bottle lasts most users well over two years, making it an exceptional long-term investment in bone and heart health.
Pros:
- Exceptional value with 900+ day supply
- Easy dose adjustment for personalized needs
- Faster absorption than solid forms
- Suitable for adults and children
Cons:
- Requires measuring each dose
- Some users prefer the convenience of capsules
Best for: Budget-conscious shoppers and families who want flexible dosing options.
4. VITBOOST D3 K2 Complex – Best High-Potency
Why it stands out: For those with significant vitamin D deficiency or higher requirements, this formula delivers 5000 IU of D3 with 90 mcg of K2 MK-7 in easy-to-swallow capsules.
The higher D3 dose makes this ideal for individuals with documented deficiency or those living in northern climates with limited sun exposure. The K2 component ensures that the increased calcium absorption from D3 gets directed to bones rather than soft tissues. At 120 capsules per bottle, you get a 4-month supply at a reasonable cost per serving.
Research shows that many people require 4000-5000 IU of D3 daily to maintain optimal blood levels, particularly if they spend most of their time indoors, have darker skin, or live above the 37th parallel. The inclusion of K2 MK-7 at 90 mcg is crucial at this D3 dose—without it, the increased calcium absorption could potentially contribute to arterial calcification. USA-made in a GMP-certified facility, this formula meets high quality standards while remaining accessible in price.
Pros:
- High-potency 5000 IU D3 for deficiency correction
- Non-GMO and gluten-free
- 4-month supply per bottle
- USA-made in GMP facility
Cons:
- May be too potent for those without deficiency
- Requires monitoring vitamin D levels
Best for: Those with diagnosed vitamin D deficiency or increased requirements due to limited sun exposure.
5. DaVinci Labs ADK 10 – Best ADK Formula
Why it stands out: This professional-grade formula adds vitamin A to the D3+K2 combination, creating a synergistic trio that supports bone health, immune function, and calcium metabolism.
DaVinci Labs is a trusted name in practitioner-quality supplements, and their ADK formula reflects that commitment to quality. The addition of vitamin A supports immune function and works synergistically with D3 and K2 for comprehensive bone health. Vegetarian capsules and a soy-free, gluten-free formulation make this accessible for most users.
The ADK combination addresses multiple aspects of bone metabolism. Vitamin A supports osteoblast (bone-building cell) function, vitamin D3 enhances calcium absorption, and K2 MK-7 ensures that calcium ends up in bones rather than arteries. This three-pronged approach is particularly popular among functional medicine practitioners and those following comprehensive bone health protocols. The 90-capsule bottle provides a 3-month supply when taken at the recommended one capsule daily.
Pros:
- Professional-grade quality from trusted brand
- Synergistic A, D3, K2 combination
- Vegetarian and allergen-free
- Supports bone, immune, and heart health
Cons:
- Higher price than basic D3+K2 formulas
- Vitamin A not needed by everyone
Best for: Those wanting a comprehensive bone support formula with professional-grade quality.
6. Nature’s Craft D3 with K2 MK-7 – Best Budget Option
Why it stands out: This affordable tablet formula delivers the essential D3+K2 combination at a price point that makes long-term supplementation accessible for everyone.
At 2000 IU of D3 with K2 MK-7 per tablet, this formula hits the sweet spot for daily maintenance supplementation. The 120-tablet bottle provides a 4-month supply at one of the lowest costs per serving in the category. Nature’s Craft focuses on immune support, bone health, heart health, and even mood support through optimal vitamin D status.
Don’t let the budget price fool you—this formula provides the same fundamental nutrients as premium options at a fraction of the cost. The 2000 IU D3 dose is appropriate for general maintenance in most adults, and the K2 MK-7 component ensures proper calcium metabolism. For those on a tight budget or wanting to test whether D3+K2 supplementation works for them before investing in premium products, this is an excellent starting point.
Pros:
- Excellent price per serving
- 4-month supply per bottle
- Well-rounded D3+K2 ratio
- Supports multiple health systems
Cons:
- Basic tablet format
- Less feature-rich than premium options
Best for: Budget-conscious consumers who want reliable D3+K2 supplementation without premium pricing.
7. Vitamin D3 K2 3000 IU – Best Mid-Range D3
Why it stands out: With 3000 IU of D3 per capsule, this formula bridges the gap between maintenance doses and high-potency options, ideal for those needing moderate vitamin D support.
The K2 component uses MK-7 derived from natto for optimal bioavailability. This mid-range D3 dose works well for those who get some sun exposure but still need supplementation, or for maintaining levels after correcting a deficiency. The 90-capsule bottle provides a 3-month supply with a straightforward once-daily dosing regimen.
The 3000 IU dose is particularly well-suited for transitional use—after you’ve corrected a deficiency with higher doses but before dropping to pure maintenance levels. It’s also appropriate for people with moderate vitamin D needs due to partial sun exposure or lighter skin tones that synthesize vitamin D more efficiently. The clean, gluten-free formulation focuses on the essentials without unnecessary additives or fillers.
Pros:
- Balanced 3000 IU dose for moderate needs
- Natto-derived MK-7 for bioavailability
- Gluten-free formulation
- 3-month supply
Cons:
- May be insufficient for severe deficiency
- Basic capsule format
Best for: Those needing moderate vitamin D support or maintenance after deficiency correction.
8. Vitamin K2 MK-7 Gummies 100mcg – Best Standalone K2
Why it stands out: For those who already supplement with vitamin D separately, these standalone K2 gummies deliver a clinical 100 mcg dose of pure MK-7 in a chewable format.
The 100 mcg MK-7 dose aligns with what clinical studies use for bone and cardiovascular benefits. Natural orange flavor makes these gummies pleasant to take daily, while the vegan and non-GMO formulation appeals to health-conscious consumers. This is ideal if you’re already taking vitamin D and want to add K2 without changing your existing regimen.
Standalone K2 supplements are valuable for those who already have a vitamin D protocol they like, whether it’s a specific brand, dose, or form. Adding these gummies lets you get K2’s calcium-directing benefits without disrupting what’s working for you. The gummy format is particularly appealing for those who take multiple supplements and appreciate variety in delivery methods. At 60 gummies per bottle, plan for monthly repurchases for consistent supplementation.
Pros:
- Clinical 100 mcg MK-7 dose
- Standalone format for flexible supplementation
- Vegan and non-GMO
- Pleasant orange flavor
Cons:
- Requires separate D3 supplement for synergy
- 60-count bottle needs monthly repurchase
Best for: Those already taking vitamin D who want to add standalone K2 supplementation.
9. Vitamin D3 5000IU + K2 + B Complex – Best Multi-Nutrient
Why it stands out: This comprehensive formula goes beyond D3+K2 by adding B vitamins (B12, B6, B9), vitamin E, and zinc for broader metabolic and immune support.
The sugar-free gummy format delivers 5000 IU of D3 with 120 mcg of K2 MK-7, plus methylated B vitamins for energy and mood support. MCT oil enhances absorption of the fat-soluble vitamins. This multi-nutrient approach simplifies your supplement routine by combining several essentials into one product.
The addition of B vitamins makes this formula particularly valuable for energy metabolism and nervous system function. Methylated forms (like methylcobalamin for B12) are more bioavailable than standard forms, especially for those with MTHFR genetic variations. The inclusion of MCT oil is a thoughtful touch—since D3 and K2 are fat-soluble, they absorb better with dietary fat, and MCT oil provides this without requiring you to take the supplement with a fatty meal. Zinc rounds out the formula with additional immune support.
Pros:
- Comprehensive multi-nutrient formula
- Sugar-free gummy format
- Methylated B vitamins for better absorption
- MCT oil enhances fat-soluble vitamin uptake
Cons:
- More complex formula than some prefer
- Higher price for additional ingredients
Best for: Those wanting to consolidate multiple supplements into one comprehensive formula.
10. Full Spectrum Vitamin K2 – Best Full Spectrum
Why it stands out: Unlike products using only MK-7, this formula includes both MK-7 and MK-4 forms of vitamin K2 at a high 600 mcg total dose for comprehensive coverage.
Different K2 forms have different tissue affinities—MK-4 concentrates in certain tissues like the brain and testes, while MK-7 has superior longevity in the bloodstream. This full-spectrum approach ensures you get benefits from both forms. The high 600 mcg dose is appropriate for those with significant bone health concerns or following therapeutic protocols.
The rationale for combining MK-7 and MK-4 comes from their complementary actions. MK-7’s longer half-life means it provides sustained carboxylation of vitamin K-dependent proteins throughout the day, while MK-4 rapidly accumulates in specific tissues where it may have unique local effects. Some practitioners prefer this approach for clients with more serious bone density concerns or those who don’t respond adequately to MK-7 alone. The 90-capsule bottle provides a 3-month supply at the recommended daily dose.
Pros:
- Full spectrum MK-7 + MK-4 coverage
- High 600 mcg therapeutic dose
- 90-capsule, 3-month supply
- Works synergistically with vitamin D3
Cons:
- Does not include vitamin D3
- High dose may be unnecessary for general maintenance
Best for: Those following therapeutic protocols or wanting comprehensive K2 coverage with multiple forms.
What is Vitamin K2 MK-7 and Who Should Take It?
Vitamin K2 MK-7 (menaquinone-7) is the most bioavailable form of vitamin K2, staying active in your bloodstream for up to 72 hours compared to just a few hours for K1 or MK-4. Its primary role is activating proteins that regulate calcium—directing it into bones and teeth while preventing it from accumulating in arteries and soft tissues. This “calcium paradox” solution makes K2 essential for anyone concerned about both bone health and cardiovascular health simultaneously.
The MK-7 form is primarily produced through bacterial fermentation, with natto (fermented soybeans) being the richest natural source. Modern supplements also derive MK-7 from chickpea fermentation, offering a soy-free alternative. Unlike vitamin K1, which the body uses primarily for blood clotting and is rapidly cleared from the bloodstream, MK-7 remains bioavailable long enough to reach tissues throughout the body where it activates osteocalcin (for bone mineralization) and matrix GLA protein (for arterial protection).
You may benefit from K2 supplementation if you take vitamin D3 (since D increases calcium absorption), have concerns about bone density, are postmenopausal, take statins (which may deplete K2), or want cardiovascular support. Clinical research has demonstrated significant benefits for arterial flexibility and bone mineral density with daily MK-7 supplementation of 100-180 mcg. Those with limited dietary intake of K2-rich foods like natto, hard cheeses, and grass-fed dairy are particularly likely to benefit from supplementation.
How to Choose the Right Vitamin K2 MK-7 Supplement
Key Ingredients to Look For
The MK-7 form of vitamin K2 is preferred over MK-4 for daily supplementation due to its longer half-life and better absorption. Look for doses of 100-200 mcg of MK-7 per serving, which aligns with clinical research showing benefits for bone density and arterial flexibility. Premium brands use trademarked ingredients like MenaQ7 (from chickpea fermentation) or VitaMK7 (from natto), which undergo rigorous purity testing to ensure they contain the bioactive “all-trans” form rather than inactive cis-isomers.
Many experts recommend combining K2 with vitamin D3, as they work synergistically—D3 increases calcium absorption while K2 ensures proper calcium placement. The ideal ratio varies by individual needs, but most combination products provide 1000-5000 IU of D3 with 45-200 mcg of K2. For comprehensive bone support, some practitioners recommend ADK formulas that also include vitamin A.
Forms Compared
Softgels and liquid drops typically offer the best absorption since K2 is fat-soluble and benefits from oil-based delivery. The fat in these formulations helps dissolve the K2 and transport it across the intestinal wall. Gummies provide convenience and palatability but may contain added sugars—look for sugar-free options if this concerns you. Capsules and tablets work well for those who prefer traditional formats, though absorption may be slightly lower than oil-based forms. Powder formulations like Toku Flow offer versatility for those who dislike swallowing pills or want to add K2 to smoothies.
What to Avoid
Steer clear of products using only vitamin K1 or synthetic menadione (K3), which don’t provide the same cardiovascular and bone benefits as natural K2. Avoid formulas with proprietary blends that don’t disclose the exact amount of K2—you need to know you’re getting a clinical dose. Check for unnecessary fillers, artificial colors, and allergens that might cause reactions. If you take blood thinners (especially warfarin/Coumadin), consult your doctor before starting K2 supplementation, as vitamin K can affect how these medications work.
Side Effects and Precautions
Vitamin K2 MK-7 has an excellent safety profile with no established upper intake limit for healthy adults. Clinical studies using doses up to 180 mcg daily for three years reported no adverse effects, and even higher doses appear well-tolerated. Most people tolerate K2 well, though rare reports of mild digestive discomfort exist, particularly when taken on an empty stomach. Taking K2 with food generally prevents any gastrointestinal issues.
The primary precaution involves blood-thinning medications, particularly vitamin K antagonists like warfarin (Coumadin). Since vitamin K is essential for blood clotting, supplementation can interfere with these medications’ effectiveness by counteracting their mechanism of action. If you take warfarin, do not start K2 supplementation without your doctor’s guidance—they may need to adjust your medication dose or monitor your INR more closely. However, newer blood thinners (DOACs like apixaban, rivaroxaban, and dabigatran) work through different mechanisms and don’t interact with vitamin K. Pregnant and nursing women should consult healthcare providers before starting supplementation, though K2 is generally considered safe during pregnancy and may even support fetal bone development.
FAQs
How much vitamin K2 MK-7 should I take daily?
Most clinical research uses 100-180 mcg of MK-7 daily. For general bone and heart health maintenance, 100 mcg is typically sufficient. Those with specific concerns about arterial stiffness or bone density may benefit from 180 mcg, which is the dose used in major cardiovascular studies.
When is the best time to take vitamin K2?
Take K2 with a meal containing some fat for optimal absorption, since it’s a fat-soluble vitamin. Many people take it with breakfast or dinner. If you’re also taking vitamin D3, taking them together is convenient and may enhance absorption of both nutrients.
How long until I see results from vitamin K2 supplementation?
Changes in vitamin K status (measured by carboxylated osteocalcin and MGP levels) can occur within weeks. However, measurable improvements in bone density or arterial stiffness typically require 1-3 years of consistent supplementation, based on clinical trial timelines.
Can I take vitamin K2 with other supplements?
Yes, K2 pairs especially well with vitamin D3, calcium, and magnesium for bone health. The combination of D3 and K2 is particularly synergistic—D3 increases calcium absorption while K2 directs that calcium to bones. Some people also combine K2 with omega-3s for comprehensive cardiovascular support.
Is vitamin K2 safe to take with blood pressure medications?
Vitamin K2 doesn’t typically interact with blood pressure medications. However, if you take vitamin K antagonist blood thinners (like warfarin), you must consult your doctor first. Newer blood thinners (DOACs) generally don’t interact with vitamin K, but always verify with your healthcare provider.
What’s the difference between MK-7 and MK-4 forms of vitamin K2?
MK-7 has a much longer half-life (72+ hours vs. a few hours for MK-4), meaning it stays active in your body longer and can be taken once daily at lower doses. MK-4 requires much higher doses (often 15-45 mg) and multiple daily servings to be effective. MK-7 is generally preferred for convenience and consistent blood levels.
Final Verdict
For most people, the Natural Vitamin D3 K2 Gummies offer the best combination of clinical dosing, convenience, and synergistic D3+K2 benefits. The gummy format makes daily compliance easy, and the 100 mcg MK-7 dose matches clinical research showing benefits for both bone density and arterial health.
If budget is your priority, the Vitamin D3 K2 Liquid Drops provide exceptional value with over 900 days of supply in one bottle—plus the flexibility to adjust dosing for different family members. For those wanting standalone K2 supplementation, the Vitamin K2 MK-7 Gummies 100mcg deliver a pure, clinical dose without vitamin D for those who supplement separately or get adequate sun exposure.
For comprehensive cardiovascular support, Toku Flow’s nattokinase combination offers unique circulatory benefits beyond basic calcium management. And for those with diagnosed vitamin D deficiency or following therapeutic protocols for bone health, the VITBOOST D3 K2 Complex or Full Spectrum Vitamin K2 provide higher doses appropriate for more aggressive supplementation strategies. Whichever you choose, consistency matters most—the benefits of K2 supplementation build over months and years of daily use.
